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Clinical risk prediction is a valuable tool for guiding healthcare interventions toward those most likely to benefit. Yet, evaluating the pairing of a risk prediction model with an intervention using randomized controlled trials presents…

Methodology · Statistics 2025-10-31 Valerie Odeh-Couvertier , Gabriel Zayas-Caban , Brian Patterson , Amy Cochran

Acceleration of machine learning research in healthcare is challenged by lack of large annotated and balanced datasets. Furthermore, dealing with measurement inaccuracies and exploiting unsupervised data are considered to be central to…

Signal Processing · Electrical Eng. & Systems 2019-01-11 Deepta Rajan , David Beymer , Girish Narayan

The Predictive Approaches to Treatment Effect Heterogeneity statement focused on baseline risk as a robust predictor of treatment effect and provided guidance on risk-based assessment of treatment effect heterogeneity in the RCT setting.…

Deep learning models for chest X-ray diagnosis are constrained by limited coverage of clinically meaningful concept combinations in publicly available training datasets. While synthetic image generation has been explored to increase data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Tackling domain shifts in multi-centre and multi-vendor data sets remains challenging for cardiac image segmentation. In this paper, we propose a generalisable segmentation framework for cardiac image segmentation in which multi-centre,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Hongwei Li , Jianguo Zhang , Bjoern Menze

Machine learning models have the potential to identify cardiovascular diseases (CVDs) early and accurately in primary healthcare settings, which is crucial for delivering timely treatment and management. Although population-based CVD risk…

High-cardinality categorical features are a common characteristic of mixed-type tabular datasets. Existing generative model architectures struggle to learn the complexities of such data at scale, primarily due to the difficulty of…

Machine Learning · Computer Science 2025-01-30 Lee Carlin , Yuval Benjamini

In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales. This is particularly clear in medicine, where the rate of clinical events varies by ward, patient, and application. Increasingly complex models have been…

Machine Learning · Computer Science 2020-03-06 Jacob Deasy , Ari Ercole , Pietro Liò

Making evidence based decisions requires data. However for real-world applications, the privacy of data is critical. Using synthetic data which reflects certain statistical properties of the original data preserves the privacy of the…

Machine Learning · Computer Science 2021-05-28 Varun Chandrasekaran , Darren Edge , Somesh Jha , Amit Sharma , Cheng Zhang , Shruti Tople

Structured output representation is a generative task explored in computer vision that often times requires the mapping of low dimensional features to high dimensional structured outputs. Losses in complex spatial information in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Mohamed Debbagh

In this study, hypertension is utilized as an indicator of individual vascular damage. This damage can be identified through machine learning techniques, providing an early risk marker for potential major cardiovascular events and offering…

Electrocardiogram (ECG) datasets tend to be highly imbalanced due to the scarcity of abnormal cases. Additionally, the use of real patients' ECGs is highly regulated due to privacy issues. Therefore, there is always a need for more ECG…

Machine Learning · Computer Science 2022-08-25 Edmond Adib , Fatemeh Afghah , John J. Prevost

Noninvasive reconstruction of cardiac transmembrane potential (TMP) from surface electrocardiograms (ECG) involves an ill-posed inverse problem. Model-constrained regularization is powerful for incorporating rich physiological knowledge…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , Jwala Dhamala , Prashnna Kumar Gyawali , John L Sapp , B. Milan Horacek , Linwei Wang

COVID-19 has caused many deaths worldwide. The automation of the diagnosis of this virus is highly desired. Convolutional neural networks (CNNs) have shown outstanding classification performance on image datasets. To date, it appears that…

Generating virtual populations of anatomy that capture sufficient variability while remaining plausible is essential for conducting in-silico trials of medical devices. However, not all anatomical shapes of interest are always available for…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Haoran Dou , Seppo Virtanen , Nishant Ravikumar , Alejandro F. Frangi

Data scarcity remains a significant challenge in the field of emotion recognition using physiological signals, as acquiring comprehensive and diverse datasets is often prevented by privacy concerns and logistical constraints. This…

Neural and Evolutionary Computing · Computer Science 2025-01-29 S. Muhammad Hossein Mousavi

The development of deep learning methods for magnetic resonance spectroscopy (MRS) is often hindered by limited availability of large, high-quality training datasets. While physics-based simulations are commonly used to mitigate this…

Myocardial infarction (MI) is a leading cause of death, and its adverse outcomes are urgent to predict. Yet ECG-based prognostic models underperform because deep learning requires large, labelled datasets, which are scarce in medicine.…

The generalizability of machine learning (ML) models for wearable monitoring in stroke rehabilitation is often constrained by the limited scale and heterogeneity of available data. Data augmentation addresses this challenge by adding…

Machine Learning · Computer Science 2024-11-01 Aaron J. Hadley , Christopher L. Pulliam

Accurate diagnosis is required before performing proper treatments for coronary heart disease. Machine learning based approaches have been proposed by many researchers to improve the accuracy of coronary heart disease diagnosis. Ensemble…

Machine Learning · Computer Science 2020-07-07 Kuntoro Adi Nugroho , Noor Akhmad Setiawan , Teguh Bharata Adji