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Accurate analysis of 3D myocardium deformation using high-resolution computerized tomography (CT) datasets with ground truth (GT) annotations is crucial for advancing cardiovascular imaging research. However, the scarcity of such datasets…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Shahar Zuler , Dan Raviv

Deep generative models have emerged as influential instruments for data generation and manipulation. Enhancing the controllability of these models by selectively modifying data attributes has been a recent focus. Variational Autoencoders…

Image and Video Processing · Electrical Eng. & Systems 2023-12-15 Maxime Di Folco , Cosmin Bercea , Julia A. Schnabel

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar

Synthetic cardiac MRI (CMRI) generation has emerged as a promising strategy to overcome the scarcity of annotated medical imaging data. Recent advances in GANs, VAEs, diffusion probabilistic models, and flow-matching techniques aim to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Ishan Kumarasinghe , Dasuni Kawya , Madhura Edirisooriya , Isuri Devindi , Isuru Nawinne , Vajira Thambawita

The estimation of patient-specific tissue properties in the form of model parameters is important for personalized physiological models. However, these tissue properties are spatially varying across the underlying anatomical model,…

Machine Learning · Statistics 2020-05-19 Jwala Dhamala , Sandesh Ghimire , John L. Sapp , B. Milan Horácek , Linwei Wang

Researchers require timely access to real-world longitudinal electronic health records (EHR) to develop, test, validate, and implement machine learning solutions that improve the quality and efficiency of healthcare. In contrast, health…

Machine Learning · Computer Science 2020-12-21 Siddharth Biswal , Soumya Ghosh , Jon Duke , Bradley Malin , Walter Stewart , Jimeng Sun

Generating power system states that have similar distribution and dependency to the historical ones is essential for the tasks of system planning and security assessment, especially when the historical data is insufficient. In this paper,…

Machine Learning · Computer Science 2022-12-14 Chenguang Wang , Simon H. Tindemans , Peter Palensky

We propose a method for synthesizing cardiac magnetic resonance (MR) images with plausible heart pathologies and realistic appearances for the purpose of generating labeled data for the application of supervised deep-learning (DL) training.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Sina Amirrajab , Cristian Lorenz , Juergen Weese , Josien Pluim , Marcel Breeuwer

Early detection of surgical complications allows for timely therapy and proactive risk mitigation. Machine learning (ML) can be leveraged to identify and predict patient risks for postoperative complications. We developed and validated the…

Machine Learning · Computer Science 2024-12-31 Junbo Shen , Bing Xue , Thomas Kannampallil , Chenyang Lu , Joanna Abraham

Acquiring annotated data at scale with rare diseases or conditions remains a challenge. It would be extremely useful to have a method that controllably synthesizes images that can correct such underrepresentation. Assuming a proper latent…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Spyridon Thermos , Xiao Liu , Alison O'Neil , Sotirios A. Tsaftaris

Controllable data generation aims to synthesize data by specifying values for target concepts. Achieving this reliably requires modeling the underlying generative factors and their relationships. In real-world scenarios, these factors…

Machine Learning · Computer Science 2025-11-21 Qilong Zhao , Shiyu Wang , Zeeshan Memon , Yang Qiao , Guangji Bai , Bo Pan , Zhaohui Qin , Liang Zhao

Analyzing data from past clinical trials is part of the ongoing effort to optimize the design, implementation, and execution of new clinical trials and more efficiently bring life-saving interventions to market. While there have been recent…

Machine Learning · Computer Science 2024-12-16 Chufan Gao , Mandis Beigi , Afrah Shafquat , Jacob Aptekar , Jimeng Sun

High-quality synthetic data can support the development of effective predictive models for biomedical tasks, especially in rare diseases or when subject to compelling privacy constraints. These limitations, for instance, negatively impact…

Machine Learning · Computer Science 2023-01-24 Lorenzo Simone , Davide Bacciu

Data preprocessing is a critical part of time series data analysis. Data from connected medical devices often have missing or abnormal values during acquisition. Handling such situations requires additional assumptions and domain knowledge.…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Ali AbuSaleh , Mehdi Rahim

Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a…

Machine Learning · Computer Science 2026-01-13 Rohit Kaushik , Eva Kaushik

Models for predicting the risk of cardiovascular events based on individual patient characteristics are important tools for managing patient care. Most current and commonly used risk prediction models have been built from carefully selected…

Cardiovascular diseases (CVD), including atherosclerosis CVD (ASCVD), are multifactorial diseases that present a major economic and social burden worldwide. Tremendous efforts have been made to understand traditional risk factors for ASCVD,…

Methodology · Statistics 2020-05-26 Thierry Chekouo , Sandra E. Safo

Cardiovascular disease remains a leading global cause of mortality, necessitating accurate risk prediction tools. Traditional methods, such as QRISK and the Framingham heart score, exhibit limitations in their ability to incorporate…

Genomics · Quantitative Biology 2024-02-12 Farnoush Shishehbori , Zainab Awan

Data augmentation is a valuable tool for the design of deep learning systems to overcome data limitations and stabilize the training process. Especially in the medical domain, where the collection of large-scale data sets is challenging and…

Machine Learning · Computer Science 2025-02-11 Mane Margaryan , Matthias Seibold , Indu Joshi , Mazda Farshad , Philipp Fürnstahl , Nassir Navab

Cardiovascular diseases (CVDs) remain the foremost cause of mortality worldwide, a burden worsened by a severe deficit of healthcare workers. Artificial intelligence (AI) agents have shown potential to alleviate this gap through automated…