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Self-Consistency mitigates hallucinations in Large Language Models (LLMs) by sampling multiple reasoning paths,but it lacks a systematic approach to determine the optimal number of samples or select the most faithful rationale. To address…

Computation and Language · Computer Science 2025-02-05 Guangya Wan , Yuqi Wu , Jie Chen , Sheng Li

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

Objective: Large Language Models (LLMs) demonstrate significant capabilities in medical text understanding and generation. However, their diagnostic reliability in complex clinical scenarios remains limited. This study aims to enhance LLMs'…

Computation and Language · Computer Science 2025-08-04 Peixian Li , Yu Tian , Ruiqi Tu , Chengkai Wu , Jingjing Ren , Jingsong Li

Recent research has shown that LLM performance on reasoning tasks can be enhanced by scaling test-time compute. One promising approach, particularly with decomposable problems, involves arranging intermediate solutions as a graph on which…

Artificial Intelligence · Computer Science 2025-03-03 Pedro Gimenes , Zeyu Cao , Jeffrey Wong , Yiren Zhao

Accurate risk assessment in lung cancer screening is critical for enabling early cancer detection and minimizing unnecessary invasive procedures. The Lung CT Screening Reporting and Data System (Lung-RADS) has been widely used as the…

Machine Learning · Computer Science 2025-09-09 Chuang Niu , Ge Wang

The rapid rise of large language models (LLMs) has shifted artificial intelligence (AI) research toward agentic systems, motivating the use of weaker and more flexible notions of agency. However, this shift raises key questions about the…

Artificial Intelligence · Computer Science 2025-10-27 Vince Trencsenyi , Agnieszka Mensfelt , Kostas Stathis

Radiotherapy treatment planning is a challenging large-scale optimization problem plagued by uncertainty. Following the robust optimization methodology, we propose a novel, spatially based uncertainty set for robust modeling of radiotherapy…

Optimization and Control · Mathematics 2024-05-28 Noam Goldberg , Mark P. Langer , Shimrit Shtern

Retrieval-augmented generation (RAG) has demonstrated significant proficiency in conducting question-answering (QA) tasks within a specified corpus. Nonetheless, numerous failure instances of RAG in QA still exist. These failures are not…

Machine Learning · Computer Science 2025-06-09 Jintao Zhang , Guoliang Li , Jinyang Su

Brain Metastases (BM) are a large contributor to mortality of patients with cancer. They are treated with Stereotactic Radiosurgery (SRS) and monitored with Magnetic Resonance Imaging (MRI) at regular follow-up intervals according to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Lorenz Achim Kuhn , Daniel Abler , Jonas Richiardi , Andreas F. Hottinger , Luis Schiappacasse , Vincent Dunet , Adrien Depeursinge , Vincent Andrearczyk

With the advancement of Agentic AI, researchers are increasingly leveraging autonomous agents to address challenges in software engineering (SE). However, the large language models (LLMs) that underpin these agents often function as black…

Software Engineering · Computer Science 2026-04-03 Jingyue Li , André Storhaug

Due to the powerful vision-language reasoning and generalization abilities, multimodal large language models (MLLMs) have garnered significant attention in the field of end-to-end (E2E) autonomous driving. However, their application to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Xueyi Liu , Zuodong Zhong , Yuxin Guo , Yun-Fu Liu , Zhiguo Su , Qichao Zhang , Junli Wang , Yinfeng Gao , Yupeng Zheng , Qiao Lin , Huiyong Chen , Dongbin Zhao

Cancer screening is a reasoning task. A radiologist observes findings, compares them to prior scans, integrates clinical context, and reaches a diagnostic conclusion confirmed by pathology. We present RadThinking, a Visual Question…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Wenxuan Li , Pedro R. A. S. Bassi , Xinze Zhou , Jakob Wasserthal , Alan L. Yuille , Zongwei Zhou

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

Nuclear waste management requires rigorous regulatory compliance assessment, demanding advanced decision-support systems capable of addressing complex legal, environmental, and safety considerations. This paper presents a multi-agent…

Multiagent Systems · Computer Science 2025-05-29 Dongjune Chang , Sola Kim , Young Soo Park

Enabling humans to identify potential flaws in an agent's decision making is an important Explainable AI application. We consider identifying such flaws in a planning-based deep reinforcement learning (RL) agent for a complex real-time…

Artificial Intelligence · Computer Science 2021-09-30 Kin-Ho Lam , Zhengxian Lin , Jed Irvine , Jonathan Dodge , Zeyad T Shureih , Roli Khanna , Minsuk Kahng , Alan Fern

Improving large language models (LLMs) for electronic health record (EHR) reasoning is essential for enabling accurate and generalizable clinical predictions. While LLMs excel at medical text understanding, they underperform on EHR-based…

Artificial Intelligence · Computer Science 2025-08-20 Yue Fang , Yuxin Guo , Jiaran Gao , Hongxin Ding , Xinke Jiang , Weibin Liao , Yongxin Xu , Yinghao Zhu , Zhibang Yang , Liantao Ma , Junfeng Zhao , Yasha Wang

With the rapid advancement of tool-use capabilities in Large Language Models (LLMs), Retrieval-Augmented Generation (RAG) is shifting from static, one-shot retrieval toward autonomous, multi-turn evidence acquisition. However, existing…

Artificial Intelligence · Computer Science 2026-02-13 Zhanli Li , Huiwen Tian , Lvzhou Luo , Yixuan Cao , Ping Luo

Sector duration optimization (SDO) is a problem arising in treatment planning for stereotactic radiosurgery on Gamma Knife. Given a set of isocenter locations, SDO aims to select collimator size configurations and irradiation times thereof…

Optimization and Control · Mathematics 2022-05-24 Oylum Şeker , Mucahit Cevik , Merve Bodur , Young Lee-Bartlett , Mark Ruschin

We present Attentive Reasoning Queries (ARQs), a novel structured reasoning approach that significantly improves instruction-following in Large Language Models through domain-specialized reasoning blueprints. While LLMs demonstrate…

Computation and Language · Computer Science 2025-03-06 Bar Karov , Dor Zohar , Yam Marcovitz

Supervised fine-tuning (SFT) has emerged as one of the most effective ways to improve the performance of large language models (LLMs) in downstream tasks. However, SFT can have difficulty generalizing when the underlying data distribution…

Computation and Language · Computer Science 2025-12-15 Mrinal Rawat , Arkajyoti Chakraborty , Neha Gupta , Roberto Pieraccini