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Related papers: CoPHo: Classifier-guided Conditional Topology Gene…

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We consider core-periphery structured graphs, which are graphs with a group of densely and sparsely connected nodes, respectively, referred to as core and periphery nodes. The so-called core score of a node is related to the likelihood of…

Machine Learning · Computer Science 2022-10-05 Sravanthi Gurugubelli , Sundeep Prabhakar Chepuri

Diffusion models have achieved impressive success in high-fidelity image generation but suffer from slow sampling due to their inherently iterative denoising process. While recent one-step methods accelerate inference by learning direct…

Machine Learning · Computer Science 2025-10-15 Hanru Bai , Weiyang Ding , Difan Zou

We characterize structures such as monotonicity, convexity, and modality in smooth regression curves using persistent homology. Persistent homology is a key tool in topological data analysis that detects higher-dimensional topological…

Algebraic Topology · Mathematics 2025-10-28 Satish Kumar , Subhra Sankar Dhar

Classifier-free guided diffusion models have recently been shown to be highly effective at high-resolution image generation, and they have been widely used in large-scale diffusion frameworks including DALLE-2, Stable Diffusion and Imagen.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Chenlin Meng , Robin Rombach , Ruiqi Gao , Diederik P. Kingma , Stefano Ermon , Jonathan Ho , Tim Salimans

Persistent Homology (PH) offers stable, multi-scale descriptors of intrinsic shape structure by capturing connected components, loops, and voids that persist across scales, providing invariants that complement purely geometric…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Prachi Kudeshia , Jiju Poovvancheri , Amr Ghoneim , Dong Chen

Representation learning on graphs is a fundamental problem that can be crucial in various tasks. Graph neural networks, the dominant approach for graph representation learning, are limited in their representation power. Therefore, it can be…

Machine Learning · Computer Science 2025-01-17 Zuoyu Yan , Qi Zhao , Ze Ye , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

The task of layout-to-image generation involves synthesizing images based on the captions of objects and their spatial positions. Existing methods still struggle in complex layout generation, where common bad cases include object missing,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Bo Cheng , Yuhang Ma , Liebucha Wu , Shanyuan Liu , Ao Ma , Xiaoyu Wu , Dawei Leng , Yuhui Yin

Scaffold hopping is a drug discovery strategy to generate new chemical entities by modifying the core structure, the \emph{scaffold}, of a known active compound. This approach preserves the essential molecular features of the original…

Biomolecules · Quantitative Biology 2023-08-16 Jos Torge , Charles Harris , Simon V. Mathis , Pietro Lio

We introduce conditional push-forward neural networks (CPFN), a generative framework for conditional distribution estimation. Instead of directly modeling the conditional density $f_{Y|X}$, CPFN learns a stochastic map…

Machine Learning · Computer Science 2025-12-23 Nicola Rares Franco , Lorenzo Tedesco

Diffusion models typically generate data through a fixed denoising trajectory that is shared across all samples. However, generation targets can differ in complexity, suggesting that a single pre-defined diffusion process may not be optimal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Yucheng Xing , Xiaodong Liu , Xin Wang

Learning visuomotor policies via behavior cloning typically involves mimicking expert demonstrations collected by human operators. However, natural human demonstrations inherently contain high-frequency noise, such as intermittent jerks,…

Robotics · Computer Science 2026-05-28 Junlin Wang

Current topology aware diffusion models face an architectural mismatch by using Gaussian noise for corruption while recovering structural features through conditional side channels To fix this we introduce PFlow T a generative model that…

Machine Learning · Computer Science 2026-05-19 Snigdha Chandan Khilar

Molecular generation with diffusion models has emerged as a promising direction for AI-driven drug discovery and materials science. While graph diffusion models have been widely adopted due to the discrete nature of 2D molecular graphs,…

Artificial Intelligence · Computer Science 2026-02-20 Hojung Jung , Rodrigo Hormazabal , Jaehyeong Jo , Youngrok Park , Kyunggeun Roh , Se-Young Yun , Sehui Han , Dae-Woong Jeong

Text-to-image diffusion models generate highly detailed textures, yet they often rely on surface appearance and fail to follow strict geometric constraints, particularly when those constraints conflict with the style implied by the text…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Antara Titikhsha , Om Kulkarni , Dharun Muthaiah

We propose a novel method for topological analysis of unweighted graphs which is based on \textit{persistent homology}. The proposed method maps the input graph to a complete weighted graph where the weighting function maps each edge to a…

Algebraic Topology · Mathematics 2020-07-31 Padraig Corcoran

In this work, we develop a pipeline that associates Persistence Diagrams to digital data via the most appropriate filtration for the type of data considered. Using a grid search approach, this pipeline determines optimal representation…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Francesco Conti , Davide Moroni , Maria Antonietta Pascali

Generative models on discrete state-spaces have a wide range of potential applications, particularly in the domain of natural sciences. In continuous state-spaces, controllable and flexible generation of samples with desired properties has…

Machine Learning · Computer Science 2025-03-27 Hunter Nisonoff , Junhao Xiong , Stephan Allenspach , Jennifer Listgarten

Alignment of large language models (LLMs) via SFT and RLHF/DPO typically ignores the global geometry of the representation space, relying instead on local token likelihoods or scalar scores. We view generation as tracing a semantic…

Computation and Language · Computer Science 2026-05-11 Yurui Pan , Ke Xu , Bo Peng

We study the problem of learning representations with controllable connectivity properties. This is beneficial in situations when the imposed structure can be leveraged upstream. In particular, we control the connectivity of an…

Machine Learning · Computer Science 2019-06-24 Christoph Hofer , Roland Kwitt , Mandar Dixit , Marc Niethammer

Learning dynamical systems from sparse observations is critical in numerous fields, including biology, finance, and physics. Even if tackling such problems is standard in general information fusion, it remains challenging for contemporary…

Machine Learning · Computer Science 2024-06-04 Ella Tamir , Arno Solin