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Graph neural networks (GNNs) have recently exploded in popularity thanks to their broad applicability to graph-related problems such as quantum chemistry, drug discovery, and high energy physics. However, meeting demand for novel GNN models…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-20 Rishov Sarkar , Stefan Abi-Karam , Yuqi He , Lakshmi Sathidevi , Cong Hao

Runtime and scalability of large neural networks can be significantly affected by the placement of operations in their dataflow graphs on suitable devices. With increasingly complex neural network architectures and heterogeneous device…

Retrosynthesis prediction is one of the fundamental challenges in organic chemistry and related fields. The goal is to find reactants molecules that can synthesize product molecules. To solve this task, we propose a new graph-to-graph…

Quantitative Methods · Quantitative Biology 2022-04-20 Zaiyun Lin , Shiqiu Yin , Lei Shi , Wenbiao Zhou , YingSheng Zhang

Continual learning entails learning a sequence of tasks and balancing their knowledge appropriately. With limited access to old training samples, much of the current work in deep neural networks has focused on overcoming catastrophic…

Machine Learning · Computer Science 2023-10-16 Yilin Lyu , Liyuan Wang , Xingxing Zhang , Zicheng Sun , Hang Su , Jun Zhu , Liping Jing

Despite their popularity, to date, the application of normalizing flows on categorical data stays limited. The current practice of using dequantization to map discrete data to a continuous space is inapplicable as categorical data has no…

Machine Learning · Computer Science 2021-01-22 Phillip Lippe , Efstratios Gavves

We address a fundamental problem in chemistry known as chemical reaction product prediction. Our main insight is that the input reactant and reagent molecules can be jointly represented as a graph, and the process of generating product…

Neural and Evolutionary Computing · Computer Science 2018-12-27 Kien Do , Truyen Tran , Svetha Venkatesh

Heterogeneous graph neural networks (HGNNs) were proposed for representation learning on structural data with multiple types of nodes and edges. To deal with the performance degradation issue when HGNNs become deep, researchers combine…

Machine Learning · Computer Science 2023-11-27 Xinyu Fu , Irwin King

The performance of flow matching and diffusion models can be greatly improved at inference time using reward alignment algorithms, yet efficiency remains a major limitation. While several algorithms were proposed, we demonstrate that a…

Machine Learning · Computer Science 2026-02-12 Peter Holderrieth , Uriel Singer , Tommi Jaakkola , Ricky T. Q. Chen , Yaron Lipman , Brian Karrer

Dynamic graphs are prevalent in real-world scenarios, where continuous structural changes induce catastrophic forgetting in graph neural networks (GNNs). While continual learning has been extended to dynamic graphs, existing methods…

Machine Learning · Computer Science 2025-12-15 Tingxu Yan , Ye Yuan

Tabular data poses unique challenges due to its heterogeneous nature, combining both continuous and categorical variables. Existing approaches often struggle to effectively capture the underlying structure and relationships within such…

Machine Learning · Computer Science 2025-04-24 Yoontae Hwang , Yongjae Lee

The recent emergence of contrastive learning approaches facilitates the application on graph representation learning (GRL), introducing graph contrastive learning (GCL) into the literature. These methods contrast semantically similar and…

Machine Learning · Computer Science 2022-06-03 Ganqu Cui , Yufeng Du , Cheng Yang , Jie Zhou , Liang Xu , Xing Zhou , Xingyi Cheng , Zhiyuan Liu

Graph Neural Networks (GNNs) are the predominant technique for learning over graphs. However, there is relatively little understanding of why GNNs are successful in practice and whether they are necessary for good performance. Here, we show…

Machine Learning · Computer Science 2020-11-04 Qian Huang , Horace He , Abhay Singh , Ser-Nam Lim , Austin R. Benson

Graph classification benchmarks, vital for assessing and developing graph neural networks (GNNs), have recently been scrutinized, as simple methods like MLPs have demonstrated comparable performance. This leads to an important question: Do…

Machine Learning · Computer Science 2024-08-14 Zhengdao Li , Yong Cao , Kefan Shuai , Yiming Miao , Kai Hwang

Continual learning approaches help deep neural network models adapt and learn incrementally by trying to solve catastrophic forgetting. However, whether these existing approaches, applied traditionally to image-based tasks, work with the…

Machine Learning · Computer Science 2022-06-27 Young D. Kwon , Jagmohan Chauhan , Abhishek Kumar , Pan Hui , Cecilia Mascolo

Domain generalization on graphs aims to develop models with robust generalization capabilities, ensuring effective performance on the testing set despite disparities between testing and training distributions. However, existing methods…

Machine Learning · Computer Science 2024-11-21 Qin Tian , Chen Zhao , Minglai Shao , Wenjun Wang , Yujie Lin , Dong Li

This work studies ensemble learning for graph neural networks (GNNs) under the popular semi-supervised setting. Ensemble learning has shown superiority in improving the accuracy and robustness of traditional machine learning by combining…

Machine Learning · Computer Science 2024-05-07 Xin Zhang , Daochen Zha , Qiaoyu Tan

The graph neural network (GNN) has been a powerful deep-learning tool in chemistry domain, due to its close connection with molecular graphs. Most GNN models collect and update atom and molecule features from the fed atom (and, in some…

Chemical Physics · Physics 2022-03-18 Yeji Kim , Yoonho Jeong , Jihoo Kim , Eok Kyun Lee , Won June Kim , Insung S. Choi

Boltzmann Generators have emerged as a promising machine learning tool for generating samples from equilibrium distributions of molecular systems using Normalizing Flows and importance weighting. Recently, Flow Matching has helped speed up…

Machine Learning · Statistics 2025-10-21 Lorenz Vaitl , Leon Klein

Deep neural networks (DNNs) excel on fixed datasets but struggle with incremental and shifting data in real-world scenarios. Continual learning addresses this challenge by allowing models to learn from new data while retaining previously…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Lu Yu , Zhe Tao , Dipam Goswami , Hantao Yao , Bartłomiej Twardowski , Joost Van de Weijer , Changsheng Xu

Scaling up autoregressive models in vision has not proven as beneficial as in large language models. In this work, we investigate this scaling problem in the context of text-to-image generation, focusing on two critical factors: whether…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Lijie Fan , Tianhong Li , Siyang Qin , Yuanzhen Li , Chen Sun , Michael Rubinstein , Deqing Sun , Kaiming He , Yonglong Tian