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Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…
Modern recommender systems face critical challenges in handling information overload while addressing the inherent limitations of multimodal representation learning. Existing methods suffer from three fundamental limitations: (1) restricted…
Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…
We present a longitudinal MR simulation framework which simulates the future neurodegenerative progression by outputting the predicted follow-up MR image and the voxel-based morphometry (VBM) map. This framework expects the patients to have…
Graph-based medical image segmentation represents anatomical structures using boundary graphs, providing fixed-topology landmarks and inherent population-level correspondences. However, their clinical adoption has been hindered by a major…
The hippocampus is a seminal structure in the most common surgically-treated form of epilepsy. Accurate segmentation of the hippocampus aids in establishing asymmetry regarding size and signal characteristics in order to disclose the likely…
We present a robust method to find region-level correspondences between shapes, which are invariant to changes in geometry and applicable across multiple shape representations. We generate simplified shape graphs by jointly decomposing the…
We introduce a framework combining geometric modeling with disease progression analysis to investigate tau deposition in Alzheimer's disease (AD) using positron emission tomography (PET) data. Focusing on the hippocampus, we construct a…
The study of physiology demonstrates that the form (shape)of anatomical structures dictates their functions, and analyzing the form of anatomies plays a crucial role in clinical research. Statistical shape modeling (SSM) is a widely used…
Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently…
The brain has computational capabilities that surpass those of modern systems, being able to solve complex problems efficiently in a simple way. Neuromorphic engineering aims to mimic biology in order to develop new systems capable of…
Understanding individual cortical development is essential for identifying deviations linked to neurodevelopmental disorders. However, current normative modelling frameworks struggle to capture fine-scale anatomical details due to their…
Statistical shape modeling (SSM) is a valuable and powerful tool to generate a detailed representation of complex anatomy that enables quantitative analysis and the comparison of shapes and their variations. SSM applies mathematics,…
Understanding the intricate mappings between visual stimuli and neural responses is a fundamental challenge in cognitive neuroscience. While current approaches predominantly align images and functional magnetic resonance imaging (fMRI)…
Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…
Significant advancements have been made in developing parametric models for digital humans, with various approaches concentrating on parts such as the human body, hand, or face. Nevertheless, connectors such as the neck have been overlooked…
In clinical applications, the utility of segmentation models is often based on the accuracy of derived downstream metrics such as organ size, rather than by the pixel-level accuracy of the segmentation masks themselves. Thus, uncertainty…
We introduce a new regression framework designed to deal with large-scale, complex data that lies around a low-dimensional manifold with noises. Our approach first constructs a graph representation, referred to as the skeleton, to capture…
In order to thrive in hostile and ever-changing natural environments, mammalian brains evolved to store large amounts of knowledge about the world and continually integrate new information while avoiding catastrophic forgetting. Despite the…
Modeling 3D humans accurately and robustly from a single image is very challenging, and the key for such an ill-posed problem is the 3D representation of the human models. To overcome the limitations of regular 3D representations, we…