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One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

We introduce a Hybrid Quantum Residual Network (HQRN) and establish an exact functional correspondence between its state evolution and the dynamics of classical networks with residual connections. When inputs are restricted to the…

Quantum Physics · Physics 2026-04-20 Junxu Li

Deep learning is one of the most successful and far-reaching strategies used in machine learning today. However, the scale and utility of neural networks is still greatly limited by the current hardware used to train them. These concerns…

Machine Learning · Computer Science 2022-01-12 Davis Arthur , Prasanna Date

Hybrid Quantum-Classical Machine Learning (ML) is an emerging field, amalgamating the strengths of both classical neural networks and quantum variational circuits on the current noisy intermediate-scale quantum devices. This paper performs…

Quantum Machine Learning (QML) offers a new paradigm for addressing complex financial problems intractable for classical methods. This work specifically tackles the challenge of few-shot credit risk assessment, a critical issue in inclusive…

We implement a hybrid quantum-classical model for image classification that compresses MNIST digit images into a low-dimensional feature space and then maps these features onto a 5-qubit quantum state. First, an autoencoder compresses each…

Quantum Physics · Physics 2025-08-01 Soumyadip Sarkar

We extend the concept of transfer learning, widely applied in modern machine learning algorithms, to the emerging context of hybrid neural networks composed of classical and quantum elements. We propose different implementations of hybrid…

Quantum Physics · Physics 2020-10-14 Andrea Mari , Thomas R. Bromley , Josh Izaac , Maria Schuld , Nathan Killoran

This paper presents a hybrid quantum-classical machine learning model for classification tasks, integrating a 4-qubit quantum circuit with a classical neural network. The quantum circuit is designed to encode the features of the Iris…

While quantum architectures are still under development, when available, they will only be able to process quantum data when machine learning algorithms can only process numerical data. Therefore, in the issues of classification or…

Machine Learning · Computer Science 2025-12-16 Rafal Potempa , Sebastian Porebski

Recently, there has been growing attention on combining quantum machine learning (QML) with classical deep learning approaches, as computational techniques are key to improving the performance of image classification tasks. This study…

Machine Learning · Computer Science 2025-10-29 Md. Farhan Shahriyar , Gazi Tanbhir , Abdullah Md Raihan Chy

Quantum computational chemistry holds great promise for simulating molecular systems more efficiently than classical methods by leveraging quantum bits to represent molecular wavefunctions. However, current implementations face significant…

Quantum Physics · Physics 2025-09-10 Weitang Li , Shi-Xin Zhang , Zirui Sheng , Cunxi Gong , Jianpeng Chen , Zhigang Shuai

This paper investigates whether hybrid quantum-classical machine learning can deliver practical improvements in financial fraud detection performance for card-based and other payment transactions. Building on a Guided Quantum Compressor…

Quantum Physics · Physics 2026-05-05 Rodrigo Chaves , Kunal Kumar , Bruno Chagas , Rory Linerud , Brannen Sorem , Javier Mancilla , Bryn Bell

One key step in performing quantum machine learning (QML) on noisy intermediate-scale quantum (NISQ) devices is the dimension reduction of the input data prior to their encoding. Traditional principle component analysis (PCA) and neural…

Quantum Physics · Physics 2020-12-01 Samuel Yen-Chi Chen , Chih-Min Huang , Chia-Wei Hsing , Ying-Jer Kao

Image classification, a pivotal task in multiple industries, faces computational challenges due to the burgeoning volume of visual data. This research addresses these challenges by introducing two quantum machine learning models that…

Quantum Physics · Physics 2024-03-29 Arsenii Senokosov , Alexandr Sedykh , Asel Sagingalieva , Basil Kyriacou , Alexey Melnikov

We consider quantum-classical hybrid machine learning in which large-scale input channels remain classical and small-scale working channels process quantum operations conditioned on classical input data. This does not require the conversion…

The aim of this paper is to introduce a quantum fusion mechanism for multimodal learning and to establish its theoretical and empirical potential. The proposed method, called the Quantum Fusion Layer (QFL), replaces classical fusion schemes…

Quantum Physics · Physics 2025-10-09 Tuyen Nguyen , Trong Nghia Hoang , Phi Le Nguyen , Hai L. Vu , Truong Cong Thang

Hierarchical quantum classifiers, such as quantum convolutional neural networks (QCNNs), represent recent progress toward designing effective and feasible architectures for quantum classification. However, their performance on near-term…

Quantum Physics · Physics 2026-02-26 Taehyun Kim , Israel F. Araujo , Daniel K. Park

In recent years, with rapid progress in the development of quantum technologies, quantum machine learning has attracted a lot of interest. In particular, a family of hybrid quantum-classical neural networks, consisting of classical and…

Quantum Physics · Physics 2021-11-01 Yixiong Chen

Advancements in the implementation of quantum hardware have enabled the acquisition of data that are intractable for emulation with classical computers. The integration of classical machine learning (ML) algorithms with these data holds…

Quantum Physics · Physics 2025-01-22 Gyungmin Cho , Dohun Kim

Quantum machine learning is one of the fields where quantum computers are expected to bring advantages over classical methods. However, the limited size of current computers restricts the exploitation of the full potential of quantum…

Quantum Physics · Physics 2025-11-10 Juan C. Boschero , Ward van der Schoot , Niels M. P. Neumann