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Generative models, particularly normalizing flows, have shown exceptional performance in learning probability distributions across various domains of physics, including statistical mechanics, collider physics, and lattice field theory. In…

Strongly Correlated Electrons · Physics 2025-01-14 Dominic Schuh , Janik Kreit , Evan Berkowitz , Lena Funcke , Thomas Luu , Kim A. Nicoli , Marcel Rodekamp

The solvation free energy (SFE) of molecules and ions is a fundamental property governing their solvation behavior and solubility. Molecular simulations offer a route to compute SFEs using alchemical free energy methods, such as…

Chemical Physics · Physics 2026-04-21 Junting Yu , Shuo-Hui Li , Ding Pan

The effect of solvent on the free energy of reaction intermediates adsorbed on electrocatalyst surfaces can significantly change the thermochemical overpotential, but accurate calculations of this are challenging. Here, we present…

Chemical Physics · Physics 2023-03-06 Björn Kirchhoff , Elvar Örn Jónsson , Timo Jacob , Hannes Jónsson

We describe in detail a recently proposed lattice-Boltzmann model for simulating flows with multiple phases and components. In particular, the focus is on the modeling of one-component fluid systems which obey non-ideal gas equations of…

comp-gas · Physics 2009-10-22 Xiaowen Shan , Hudong Chen

We consider fixed points of steady solutions and flow directions using the boson Boltzmann equation that is a one-dimensionally reduced kinetic equation after the angular integration. With an elastic collision integral of the two-to-two…

High Energy Physics - Phenomenology · Physics 2017-10-11 Kenji Fukushima , Koichi Murase , Shi Pu

This work presents a rigorous statistical mechanical theory of solvation free energies, specifically useful for describing the long-range nature of ions in an electrolyte solution. The theory avoids common issues with field theories by…

Statistical Mechanics · Physics 2017-12-29 David M. Rogers

In this work the free energy of solid phases is computed for the Lennard-Jones potential and for a model of NaCl. The free energy is evaluated through the Einstein crystal/molecule methodologies using the Molecular Dynamics programs:…

Soft Condensed Matter · Physics 2012-10-16 J. L. Aragones , C. Valeriani , C. Vega

Accurate phase diagram calculation from molecular dynamics requires systematic treatment and convergence of statistical averages. In this work we propose a Gaussian process regression based framework for reconstructing the free energy…

Computational Physics · Physics 2021-11-02 V. Ladygin , I. Beniya , E. Makarov , A. Shapeev

Data scarcity, bias, and experimental noise are all frequently encountered problems in the application of deep learning to chemical and material science disciplines. Transfer learning has proven effective in compensating for the lack in…

Chemical Physics · Physics 2021-03-16 Florence H. Vermeire , William H. Green

A fundamental challenge in computer analysis of power flow is the rigorous understanding of the impact of different loading levels on the solutions of the power flow equation. This letter presents a comprehensive study of possible numerical…

Signal Processing · Electrical Eng. & Systems 2019-09-06 Dan Wu , Bin Wang , Kai Sun , Le Xie

Combining analytical and numerical methods, we study within the framework of the homogeneous non-linear Boltzmann equation, a broad class of models relevant for the dynamics of dissipative fluids, including granular gases. We use the new…

Statistical Mechanics · Physics 2007-09-23 E. Trizac , A. Barrat , M. H. Ernst

The simulation of thermochemical nonequilibrium for the atomic and molecular energy level populations in plasma flows requires a comprehensive modeling of all the elementary collisional and radiative processes involved. Coupling detailed…

Plasma Physics · Physics 2019-09-04 Stefano Boccelli , Federico Bariselli , Bruno Dias , Thierry E. Magin

Alchemical free energy calculations via molecular dynamics have been widely used to obtain thermodynamic properties related to protein-ligand binding and solute-solvent interactions. Although soft-core modeling is the most common approach,…

Computational Physics · Physics 2023-01-03 Gabriela B. Correa , Jessica C. S. L. Maciel , Frederico W. Tavares , Charlles R. A. Abreu

A jump-diffusion process along with a particle scheme is devised as an accurate and efficient particle solution to the Boltzmann equation. The proposed process (hereafter Gamma-Boltzmann model) is devised to match the evolution of all…

Computational Physics · Physics 2023-08-09 Fabian Mies , Mohsen Sadr , Manuel Torrilhon

Normalizing flows are a class of deep generative models that are especially interesting for modeling probability distributions in physics, where the exact likelihood of flows allows reweighting to known target energy functions and computing…

Machine Learning · Statistics 2023-11-27 Leon Klein , Andreas Krämer , Frank Noé

Inspired by the recent development on calculating the free energy change via a relaxation process [Nat. Phys. 14, 842 (2018)], we investigate the role of heat released in an irreversible relaxation following a large perturbation. Utilizing…

A simple technique is proposed for numerically determining equilibrium ion distribution functions belonging to free energies of the Poisson-Boltzmann type. The central idea is to perform a conventional Monte-Carlo simulation using the free…

Soft Condensed Matter · Physics 2009-10-31 Markus Deserno

Flows are exact-likelihood generative neural networks that transform samples from a simple prior distribution to the samples of the probability distribution of interest. Boltzmann Generators (BG) combine flows and statistical mechanics to…

Machine Learning · Statistics 2019-10-03 Jonas Köhler , Leon Klein , Frank Noé

Estimating the free energy in molecular simulation requires, implicitly or explicitly, counting how many times the system is observed in a finite region. If the simulation is biased by an external potential, the weight of the configurations…

Chemical Physics · Physics 2021-12-22 Matteo Carli , Alessandro Laio

Molecular Density Functional Theory (MDFT) offers an efficient implicit- solvent method to estimate molecule solvation free-energies whereas conserving a fully molecular representation of the solvent. Even within a second order ap-…

Soft Condensed Matter · Physics 2014-06-12 Volodymyr P. Sergiievskyi , Guillaume Jeanmairet , Maximilien Levesque , Daniel Borgis