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Noise manifests ubiquitously in nonlinear spectroscopy, where multiple sources contribute to experimental signals generating interrelated unwanted components, from random point-wise fluctuations to structured baseline signals. Mitigating…

Raman spectroscopy can provide insight into the molecular composition of cells and tissue. Consequently, it can be used as a powerful diagnostic tool, e.g. to help identify changes in molecular contents with the onset of disease. But robust…

Medical Physics · Physics 2023-08-02 Ciaran Bench , Mads S. Bergholt , Mohamed Ali al-Badri

Raman spectroscopy enables non-destructive, label-free imaging with unprecedented molecular contrast but is limited by slow data acquisition, largely preventing high-throughput imaging applications. Here, we present a comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2021-12-02 Conor C. Horgan , Magnus Jensen , Anika Nagelkerke , Jean-Phillipe St-Pierre , Tom Vercauteren , Molly M. Stevens , Mads S. Bergholt

In many scientific applications, measured time series are corrupted by noise or distortions. Traditional denoising techniques often fail to recover the signal of interest, particularly when the signal-to-noise ratio is low or when certain…

Machine Learning · Computer Science 2022-11-02 Natalie Klein , Amber J. Day , Harris Mason , Michael W. Malone , Sinead A. Williamson

Deep learning had already demonstrated its power in medical images, including denoising, classification, segmentation, etc. All these applications are proposed to automatically analyze medical images beforehand, which brings more…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Shao-Cheng Wen , Yu-Jen Chen , Zihao Liu , Wujie Wen , Xiaowei Xu , Yiyu Shi , Tsung-Yi Ho , Qianjun Jia , Meiping Huang , Jian Zhuang

Raman spectroscopy has attracted interest as a non-invasive optical technique to study the composition and structure of a wide range of materials at the microscopic level. The intrinsic fluorescence background can be orders of magnitude…

Materials Science · Physics 2015-10-28 P. J. Cadusch , M. M. Hlaing , S. A. Wade , S. L. McArthur , P. R. Stoddart

In a normal indoor environment, Raman spectrum encounters noise often conceal spectrum peak, leading to difficulty in spectrum interpretation. This paper proposes deep learning (DL) based noise reduction technique for Raman spectroscopy.…

Signal Processing · Electrical Eng. & Systems 2020-09-10 Liangrui Pan , Pronthep Pipitsunthonsan , Peng Zhang , Chalongrat Daengngam , Apidach Booranawong , Mitcham Chongcheawchamnan

A significant research problem of recent interest is the localization of targets like vessels, surgical needles, and tumors in photoacoustic (PA) images. To achieve accurate localization, a high photoacoustic signal-to-noise ratio (SNR) is…

Image and Video Processing · Electrical Eng. & Systems 2021-05-03 Amirsaeed Yazdani , Sumit Agrawal , Kerrick Johnstonbaugh , Sri-Rajasekhar Kothapalli , Vishal Monga

Raman spectroscopy is widely used across scientific domains to characterize the chemical composition of samples in a non-destructive, label-free manner. Many applications entail the unmixing of signals from mixtures of molecular species to…

In spectroscopic experiments, data acquisition in multi-dimensional phase space may require long acquisition time, owing to the large phase space volume to be covered. In such case, the limited time available for data acquisition can be a…

The high-content image-based assay is commonly leveraged for identifying the phenotypic impact of genetic perturbations in biology field. However, a persistent issue remains unsolved during experiments: the interferential technical noise…

Image and Video Processing · Electrical Eng. & Systems 2022-12-09 Sen Yang , Tao Shen , Yuqi Fang , Xiyue Wang , Jun Zhang , Wei Yang , Junzhou Huang , Xiao Han

Spectroscopic photoacoustic (sPA) imaging uses multiple wavelengths to differentiate chromophores based on their unique optical absorption spectra. This technique has been widely applied in areas such as vascular mapping, tumor detection,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Fangzhou Lin , Shang Gao , Yichuan Tang , Xihan Ma , Ryo Murakami , Ziming Zhang , John D. Obayemi , Winston W. Soboyejo , Haichong K. Zhang

Reconstruction of magnetic resonance imaging (MRI) data has been positively affected by deep learning. A key challenge remains: to improve generalisation to distribution shifts between the training and testing data. Most approaches aim to…

Image and Video Processing · Electrical Eng. & Systems 2024-02-15 Yuyang Xue , Chen Qin , Sotirios A. Tsaftaris

Microstructure imaging is crucial in materials science, but experimental images often introduce noise that obscures critical structural details. This study presents a novel deep learning approach for robust microstructure image denoising,…

Materials Science · Physics 2025-07-03 Owais Ahmad , Albert Linda , Saumya Ranjan Jha , Somnath Bhowmick

Machine learning (ML) methods are extraordinarily successful at denoising photographic images. The application of such denoising methods to scientific images is, however, often complicated by the difficulty in experimentally obtaining a…

On one hand, the transmitted ultrasound beam gets attenuated as propagates through the tissue. On the other hand, the received Radio-Frequency (RF) data contains an additive Gaussian noise which is brought about by the acquisition card and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Sobhan Goudarzi , Hassan Rivaz

Spectrum sensing is a key technology for cognitive radios. We present spectrum sensing as a classification problem and propose a sensing method based on deep learning classification. We normalize the received signal power to overcome the…

Signal Processing · Electrical Eng. & Systems 2019-09-16 Shilian Zheng , Shichuan Chen , Peihan Qi , Huaji Zhou , Xiaoniu Yang

Hyperspectral imaging has been widely used for spectral and spatial identification of target molecules, yet often contaminated by sophisticated noise. Current denoising methods generally rely on independent and identically distributed noise…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Guangrui Ding , Chang Liu , Jiaze Yin , Xinyan Teng , Yuying Tan , Hongjian He , Haonan Lin , Lei Tian , Ji-Xin Cheng

Raman spectroscopy has attracted significant attention in various biochemical detection fields, especially in the rapid identification of pathogenic bacteria. The integration of this technology with deep learning to facilitate automated…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Haiming Yao , Wei Luo , Ang Gao , Tao Zhou , Xue Wang

Super-resolution and denoising are ill-posed yet fundamental image restoration tasks. In blind settings, the degradation kernel or the noise level are unknown. This makes restoration even more challenging, notably for learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Majed El Helou , Ruofan Zhou , Sabine Süsstrunk
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