Related papers: PathFLIP: Fine-grained Language-Image Pretraining …

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

As a pioneering vision-language model, CLIP (Contrastive Language-Image Pre-training) has achieved significant success across various domains and a wide range of downstream vision-language tasks. However, the text encoders in popular CLIP…

Recent advances in vision-language models (VLMs) have shown remarkable potential in bridging visual and textual modalities. In computational pathology, domain-specific VLMs, which are pre-trained on extensive histopathology image-text…

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…

In this paper, we introduce DetailCLIP: A Detail-Oriented CLIP to address the limitations of contrastive learning-based vision-language models, particularly CLIP, in handling detail-oriented and fine-grained tasks like segmentation. While…

Multiple instance learning (MIL)-based framework has become the mainstream for processing the whole slide image (WSI) with giga-pixel size and hierarchical image context in digital pathology. However, these methods heavily depend on a…

CLIP is a seminal multimodal model that maps images and text into a shared representation space through contrastive learning on billions of image-caption pairs. Inspired by the rapid progress of large language models (LLMs), we investigate…

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Medical image segmentation is a cornerstone of computer-assisted diagnosis and treatment planning. While recent multimodal vision-language models have shown promise in enhancing semantic understanding through textual descriptions, their…

Vision-Language Pre-training (VLP) models like CLIP have significantly advanced Remote Sensing Image-Text Retrieval (RSITR). However, existing methods predominantly rely on coarse-grained global alignment, which often overlooks the dense,…

Language-image pre-training is an effective technique for learning powerful representations in general domains. However, when directly turning to person representation learning, these general pre-training methods suffer from unsatisfactory…

Recent advances in vision language models (VLMs) have enabled broad progress in the general medical field. However, pathology still remains a more challenging subdomain, with current pathology specific VLMs exhibiting limitations in both…

This paper proposes Comprehensive Pathology Language Image Pre-training (CPLIP), a new unsupervised technique designed to enhance the alignment of images and text in histopathology for tasks such as classification and segmentation. This…

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration…

Unsupervised large-scale vision-language pre-training has shown promising advances on various downstream tasks. Existing methods often model the cross-modal interaction either via the similarity of the global feature of each modality which…

Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios.…

Contrastive Language-Image Pre-training (CLIP) excels in multimodal tasks such as image-text retrieval and zero-shot classification but struggles with fine-grained understanding due to its focus on coarse-grained short captions. To address…

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…