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The latest advancements in AI and deep learning have led to a breakthrough in large language model (LLM)-based agents such as GPT-4. However, many commercial conversational agent development tools are pipeline-based and have limitations in…

Computation and Language · Computer Science 2023-09-08 Mina Foosherian , Hendrik Purwins , Purna Rathnayake , Touhidul Alam , Rui Teimao , Klaus-Dieter Thoben

Large Language Models (LLMs) are transforming artificial intelligence, enabling autonomous agents to perform diverse tasks across various domains. These agents, proficient in human-like text comprehension and generation, have the potential…

Artificial Intelligence · Computer Science 2024-04-10 Saikat Barua

We investigate and observe the behaviour and performance of Large Language Model (LLM)-backed chatbots in addressing misinformed prompts and questions with demographic information within the domains of Climate Change and Mental Health.…

We present an outline of the first large language model (LLM) based chatbot application in the context of patient-reported outcome measures (PROMs) for diabetic retinopathy. By utilizing the capabilities of current LLMs, we enable patients…

Computation and Language · Computer Science 2024-11-06 Maren Pielka , Tobias Schneider , Jan Terheyden , Rafet Sifa

In recent years, generative AI has undergone major advancements, demonstrating significant promise in augmenting human productivity. Notably, large language models (LLM), with ChatGPT-4 as an example, have drawn considerable attention.…

Human-Computer Interaction · Computer Science 2024-01-23 Sida Peng , Wojciech Swiatek , Allen Gao , Paul Cullivan , Haoge Chang

The startling success of ChatGPT and other large language models (LLMs) using transformer-based generative neural network architecture in applications such as natural language processing and image synthesis has many researchers excited…

Artificial Intelligence · Computer Science 2024-11-05 Venkat Venkatasubramanian , Arijit Chakraborty

Large language models (LLMs) have demonstrated impressive capabilities in natural language processing. However, their internal mechanisms are still unclear and this lack of transparency poses unwanted risks for downstream applications.…

Computation and Language · Computer Science 2023-11-30 Haiyan Zhao , Hanjie Chen , Fan Yang , Ninghao Liu , Huiqi Deng , Hengyi Cai , Shuaiqiang Wang , Dawei Yin , Mengnan Du

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Computation and Language · Computer Science 2024-04-23 Zhe He , Balu Bhasuran , Qiao Jin , Shubo Tian , Karim Hanna , Cindy Shavor , Lisbeth Garcia Arguello , Patrick Murray , Zhiyong Lu

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient…

Computation and Language · Computer Science 2024-10-10 Saadia Gabriel , Isha Puri , Xuhai Xu , Matteo Malgaroli , Marzyeh Ghassemi

This paper explores the potential of constructing an AI spoken dialogue system that "thinks how to respond" and "thinks how to speak" simultaneously, which more closely aligns with the human speech production process compared to the current…

Computation and Language · Computer Science 2023-09-21 Xinyu Zhou , Delong Chen , Yudong Chen

Purpose: To assess the alignment of GPT-4-based evaluation to human clinician experts, for the evaluation of responses to ophthalmology-related patient queries generated by fine-tuned LLM chatbots. Methods: 400 ophthalmology questions and…

Artificial Intelligence · Computer Science 2024-02-16 Ting Fang Tan , Kabilan Elangovan , Liyuan Jin , Yao Jie , Li Yong , Joshua Lim , Stanley Poh , Wei Yan Ng , Daniel Lim , Yuhe Ke , Nan Liu , Daniel Shu Wei Ting

The advent of large language models (LLMs), such as GPT, Gemini, and DeepSeek, has significantly advanced natural language processing, giving rise to sophisticated chatbots capable of diverse language-related tasks. The transition from…

Computation and Language · Computer Science 2025-06-16 Jiachen Zhu , Menghui Zhu , Renting Rui , Rong Shan , Congmin Zheng , Bo Chen , Yunjia Xi , Jianghao Lin , Weiwen Liu , Ruiming Tang , Yong Yu , Weinan Zhang

Engaging in smooth conversations with others is a crucial social skill. However, differences in knowledge between conversation participants can sometimes hinder effective communication. To tackle this issue, this study proposes a real-time…

Human-Computer Interaction · Computer Science 2025-06-23 Yuichiro Fujimoto

Building trustworthy clinical AI systems requires not only accurate predictions but also transparent, biologically grounded explanations. We present \texttt{DiagnoLLM}, a hybrid framework that integrates Bayesian deconvolution, eQTL-guided…

Artificial Intelligence · Computer Science 2025-11-18 Bowen Xu , Xinyue Zeng , Jiazhen Hu , Tuo Wang , Adithya Kulkarni

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Specialized clinical AI assistants are rapidly entering medical practice, often framed as safer or more reliable than general-purpose large language models (LLMs). Yet, unlike frontier models, these clinical tools are rarely subjected to…

Computation and Language · Computer Science 2025-12-02 Krithik Vishwanath , Mrigayu Ghosh , Anton Alyakin , Daniel Alexander Alber , Yindalon Aphinyanaphongs , Eric Karl Oermann

The integration of Computer-Aided Diagnosis (CAD) with Large Language Models (LLMs) presents a promising frontier in clinical applications, notably in automating diagnostic processes akin to those performed by radiologists and providing…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Zihao Zhao , Sheng Wang , Jinchen Gu , Yitao Zhu , Lanzhuju Mei , Zixu Zhuang , Zhiming Cui , Qian Wang , Dinggang Shen

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan