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We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

Histology imaging is an important tool in medical diagnosis and research, enabling the examination of tissue structure and composition at the microscopic level. Understanding the underlying molecular mechanisms of tissue architecture is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Ronald Xie , Kuan Pang , Sai W. Chung , Catia T. Perciani , Sonya A. MacParland , Bo Wang , Gary D. Bader

The remote sensing image change detection task is an essential method for large-scale monitoring. We propose HSANet, a network that uses hierarchical convolution to extract multi-scale features. It incorporates hybrid self-attention and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Chengxi Han , Xiaoyu Su , Zhiqiang Wei , Meiqi Hu , Yichu Xu

The paper is motivated from clustering problem in high-throughput mixed datasets. Clustering of such datasets can provide much insight into biological associations. An open problem in this context is to simultaneously cluster…

Methodology · Statistics 2018-08-15 Chetkar Jha

In medical imaging, chromosome straightening plays a significant role in the pathological study of chromosomes and in the development of cytogenetic maps. Whereas different approaches exist for the straightening task, typically geometric…

Computer Vision and Pattern Recognition · Computer Science 2021-10-20 Sifan Song , Daiyun Huang , Yalun Hu , Chunxiao Yang , Jia Meng , Fei Ma , Frans Coenen , Jiaming Zhang , Jionglong Su

Essential life processes take place across multiple space and time scales in living organisms but understanding their mechanistic interactions remains an ongoing challenge. Advanced multiscale modeling techniques are providing new…

Molecular Networks · Quantitative Biology 2025-04-08 Achal Mahajan , Erik J. Navarro , William Poole , Carlos F Lopez

High-throughput spectrometers are capable of producing data sets containing thousands of spectra for a single biological sample. These data sets contain a substantial amount of redundancy from peptides that may get selected multiple times…

Data Structures and Algorithms · Computer Science 2013-01-08 Fahad Saeed , Trairak Pisitkun , Mark A. Knepper , Jason D. Hoffert

The computational resources required to train a model have been increasing since the inception of deep networks. Training neural networks on massive datasets have become a challenging and time-consuming task. So, there arises a need to…

Machine Learning · Computer Science 2022-09-07 Devvrat Joshi , Janvi Thakkar , Siddharth Soni , Shril Mody , Rohan Patil , Nipun Batra

Clustering is indispensable for data analysis in many scientific disciplines. Detecting clusters from heavy noise remains challenging, particularly for high-dimensional sparse data. Based on graph-theoretic framework, the present paper…

Computer Vision and Pattern Recognition · Computer Science 2014-07-08 Deli Zhao , Xiaoou Tang

Point cloud completion is essential for robotic perception, object reconstruction and supporting downstream tasks like grasp planning, obstacle avoidance, and manipulation. However, incomplete geometry caused by self-occlusion and sensor…

Robotics · Computer Science 2025-09-18 Yadan Zeng , Jiadong Zhou , Xiaohan Li , I-Ming Chen

Hierarchical clustering is an effective and efficient approach widely used for classical image segmentation methods. However, many existing methods using neural networks generate segmentation masks directly from per-pixel features,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Teppei Suzuki

Motivation: Cellular Electron CryoTomography (CECT) enables 3D visualization of cellular organization at near-native state and in sub-molecular resolution, making it a powerful tool for analyzing structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2017-04-14 Min Xu , Xiaoqi Chai , Hariank Muthakana , Xiaodan Liang , Ge Yang , Tzviya Zeev-Ben-Mordehai , Eric Xing

Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties.…

Human-Computer Interaction · Computer Science 2025-08-21 Mohit Sharma , Emma Nilsson , Martin Falk , Talha Bin Masood , Lee Jollans , Anders Persson , Tino Ebbers , Ingrid Hotz

Persistent homology has been devised as a promising tool for the topological simplification of complex data. However, it is computationally intractable for large data sets. In this work, we introduce multiresolution persistent homology for…

Biomolecules · Quantitative Biology 2015-04-02 Kelin Xia , Zhixiong Zhao , Guo-Wei Wei

The task of clustering a set of objects based on multiple sources of data arises in several modern applications. We propose an integrative statistical model that permits a separate clustering of the objects for each data source. These…

Machine Learning · Statistics 2015-12-01 Eric F. Lock , David B. Dunson

In various verification systems, Restricted Boltzmann Machines (RBMs) have demonstrated their efficacy in both front-end and back-end processes. In this work, we propose the use of RBMs to the image clustering tasks. RBMs are trained to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Abraham Woubie , Enoch Solomon , Eyael Solomon Emiru

Molecular subtyping of breast cancer is crucial for personalized treatment and prognosis. Traditional classification approaches rely on either histopathological images or gene expression profiling, limiting their predictive power. In this…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Amin Honarmandi Shandiz

The clustering of data into physically meaningful subsets often requires assumptions regarding the number, size, or shape of the subgroups. Here, we present a new method, simultaneous coherent structure coloring (sCSC), which accomplishes…

Machine Learning · Statistics 2019-11-26 Brooke E. Husic , Kristy L. Schlueter-Kuck , John O. Dabiri

Hyperspectral image (HSI) clustering has been a fundamental but challenging task with zero training labels. Currently, some deep graph clustering methods have been successfully explored for HSI due to their outstanding performance in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Yao Ding , Weijie Kang , Aitao Yang , Zhili Zhang , Junyang Zhao , Jie Feng , Danfeng Hong , Qinhe Zheng

Humans possess an innate ability to group objects by similarity, a cognitive mechanism that clustering algorithms aim to emulate. Recent advances in community detection have enabled the discovery of configurations -- valid hierarchical…

Machine Learning · Computer Science 2025-10-23 Juntang Wang , Hao Wu , Runkun Guo , Yihan Wang , Dongmian Zou , Shixin Xu