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Allostery, the intriguing phenomenon of long-range communication between distant sites in proteins, plays a central role in biomolecular regulation and signal transduction. While it is commonly attributed to conformational rearrangements,…

Atomic and Molecular Clusters · Physics 2026-04-29 Emanuel Dorbath , Fabian Rudolf , Adnan Gulzar , Gerhard Stock

Synthesizable molecular design (also known as synthesizable molecular optimization) is a fundamental problem in drug discovery, and involves designing novel molecular structures to improve their properties according to drug-relevant oracle…

Machine Learning · Computer Science 2026-05-07 Dannong Wang , Jintai Chen , Yingzhou Lu , Minjie Shen , Lulu Chen , Zhiding Liang , Tianfan Fu , Xiao-Yang Liu

Mechanophores, stimuli-responsive molecules that respond chromatically to mechanochemical reactions, are important for understanding the coupling between mechanics and chemistry as well as in engineering applications. However, the…

Materials Science · Physics 2022-11-30 Brenden W. Hamilton , Alejandro Strachan

Molecular Communication (MC) is an important nanoscale communication paradigm, which is employed for the interconnection of the nanomachines (NMs) to form nanonetworks. A transmitter NM (TN) sends the information symbols by emitting…

Signal Processing · Electrical Eng. & Systems 2020-03-27 Baris Atakan , Fatih Gulec

This paper describes a design of a molecular propagation system in molecular communication. Molecular communication is a new communication paradigm where biological and artificially-created nanomachines communicate over a short distance…

Biological Physics · Physics 2007-08-15 Satoshi Hiyama , Y. Isogawa , T. Suda , Y. Moritani , Kazuo Sutoh

In this paper piezoconductivity phenomenon in MOSFET channel is discussed and extension of drain current model with possibility of stress consideration is proposed. Analysis of obtained model combined with examination of stress components…

Mesoscale and Nanoscale Physics · Physics 2017-11-13 Zenon Gniazdowski

Through the use of strain and induced piezoelectric fields, surface acoustic waves have been shown to control quantum information processes, such as single photon emission and the coherent transport of electron spins. Regarding the latter,…

Applied Physics · Physics 2024-11-14 Karanpreet Singh , Gabe Wilson , James A. H. Stotz

We devised a general heterogeneous microstructural design methodology applied to a specific material system, elasto-electro-active piezoelectric ceramic embedded plastics, which has great potential in sensing, 5G communication, and energy…

Materials Science · Physics 2025-07-25 Mohammad Saber Hashemi , Khiem Nguyen , Levi Kirby , Xuan Song , Azadeh Sheidaei

Mechanosensitive (MS) channels are ion channels which act as cells' safety valves, opening when the osmotic pressure becomes too high and making cells avoid damage by releasing ions. They are found on the cellular membrane of a large number…

Biological Physics · Physics 2017-08-30 Lucas D. Fernandes , Ksenia Guseva , Alessandro P. S. de Moura

We present an analytical theory for heteropolymer deformation, as exemplified experimentally by stretching of single protein molecules. Using a mean-field replica theory, we determine phase diagrams for stress-induced unfolding of typical…

Statistical Mechanics · Physics 2009-11-07 Phillip L. Geissler , Eugene I. Shakhnovich

Mechanosensation is a key part of the sensory repertoire of a vast array of different cells and organisms. The molecular dissection of the origins of mechanosensation is rapidly advancing as a result of both structural and functional…

Subcellular Processes · Quantitative Biology 2007-05-23 Tristan Ursell , Rob Phillips , Jane' Kondev , Dan Reeves , Paul A. Wiggins

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

Biological Physics · Physics 2017-03-30 Isabella R. Graf , Erwin Frey

The network studied here is based on a standard model in physics, but it appears in various applications ranging from spintronics to neuroscience. When the network is forced by an external signal common to all its elements, there are shown…

Adaptation and Self-Organizing Systems · Physics 2020-08-18 Frank Hoppensteadt

The kinetics of a 2A + B2 = 2AB reaction on supported metal catalyst with spillover effects is investigated using Dynamic Monte Carlo simulations. In the presented model A particles can adsorb reversibly on both metal clusters and the…

Chemical Physics · Physics 2007-05-23 Lukasz Cwiklik , Barbara Jagoda-Cwiklik , Marek Frankowicz

Autoencoders have been widely used for dimensional reduction and feature extraction. Various types of autoencoders have been proposed by introducing regularization terms. Most of these regularizations improve representation learning by…

Machine Learning · Computer Science 2020-06-26 Yuzhu Guo , Kang Pan , Simeng Li , Zongchang Han , Kexin Wang , Li Li

Strain-mediated voltage control of magnetization in piezoelectric/ferromagnetic systems is a promising mechanism to implement energy-efficient spintronic memory devices. Here, we demonstrate giant voltage manipulation of MgO magnetic tunnel…

Mesoscale and Nanoscale Physics · Physics 2016-09-02 Zhengyang Zhao , Mahdi Jamali , Noel D'Souza , Delin Zhang , Supriyo Bandyopadhyay , Jayasimha Atulasimha , Jian-Ping Wang

Energy harvesting (EH) is a multidisciplinary research area, involving physics, materials science and engineering, with the objective of providing renewable sources of sufficient power to operate targeted low-power applications.…

Classical Physics · Physics 2012-04-03 Michele Pozzi

Using numerical simulations, we examine a simple model of two or more coupled one-dimensional channels of driven particles with repulsive interactions in the presence of quenched disorder. We find that this model exhibits a remarkably rich…

Statistical Mechanics · Physics 2015-05-28 C. Reichhardt , C. J. Olson Reichhardt

Chemical algorithms are statistical algorithms described and represented as chemical reaction networks. They are particularly attractive for traffic shaping and general control of network dynamics; they are analytically tractable, they…

Emerging Technologies · Computer Science 2016-01-21 Massimo Monti , Manolis Sifalakis , Christian F. Tschudin , Marco Luise

Understanding the link between structure and function in proteins is fundamental in molecular biology and proteomics. A central question in this context is whether allostery - where the binding of a molecule at one site affects the activity…

Statistical Mechanics · Physics 2025-06-02 Giulio Costantini , Lorenzo Caprini , Umberto Marini Bettolo Marconi , Fabio Cecconi