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Fundus image quality is crucial for diagnosing eye diseases, but real-world conditions often result in blurred or unreadable images, increasing diagnostic uncertainty. To address these challenges, this study proposes RetinaRegen, a hybrid…

Image and Video Processing · Electrical Eng. & Systems 2025-02-28 Yuhan Tang , Yudian Wang , Weizhen Li , Ye Yue , Chengchang Pan , Honggang Qi

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

In this paper, a hierarchical image matting model is proposed to extract blood vessels from fundus images. More specifically, a hierarchical strategy utilizing the continuity and extendibility of retinal blood vessels is integrated into the…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 Zhun Fan , Jiewei Lu , Wenji Li , Caimin Wei , Han Huang , Xinye Cai , Xinjian Chen

A retinal vessel analysis is a procedure that can be used as an assessment of risks to the eye. This work proposes an unsupervised multimodal approach that improves the response of the Frangi filter, enabling automatic vessel segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2026-05-21 Erick O Rodrigues , Lucas O Rodrigues , João HP Machado , Dalcimar Casanova , Marcelo Teixeira , Jeferson T Oliva , Giovani Bernardes , Panos Liatsis

Registration is a core component of many imaging pipelines. In case of clinical scans, with lower resolution and sometimes substantial motion artifacts, registration can produce poor results. Visual assessment of registration quality in…

Retinal vessel information is helpful in retinal disease screening and diagnosis. Retinal vessel segmentation provides useful information about vessels and can be used by physicians during intraocular surgery and retinal diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2018-02-23 M. Hajabdollahi , R. Esfandiarpoor , S. M. R. Soroushmehr , N. Karimi , S. Samavi , K. Najarian

Accurate retinal vessel segmentation is an important task for many computer-aided diagnosis systems. Yet, it is still a challenging problem due to the complex vessel structures of an eye. Numerous vessel segmentation methods have been…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Ali Karaali , Rozenn Dahyot , Donal J. Sexton

Purpose: Deep learning methods have shown promising results in the segmentation, and detection of diseases in medical images. However, most methods are trained and tested on data from a single source, modality, organ, or disease type,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Nchongmaje Ndipenocha , Alina Mirona , Kezhi Wanga , Yongmin Li

Many studies regarding the vasculature of biological tissues involve the segmentation of the blood vessels in a sample followed by the creation of a graph structure to model the vasculature. The graph is then used to extract relevant…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 João Pedro Parella , Matheus Viana da Silva , Cesar Henrique Comin

The Computer-Assisted Diagnosis systems could save workloads and give objective diagnostic to ophthalmologists. At first, feature extraction is a fundamental step. One of these retinal features is the fovea. The fovea is a small fossa on…

Medical Physics · Physics 2020-04-21 Meysam Tavakoli , Patrick Kelley , Mahdieh Nazar , Faraz Kalantari

Background: Increased pericardial adipose tissue (PAT) is associated with many types of cardiovascular disease (CVD). Although cardiac magnetic resonance images (CMRI) are often acquired in patients with CVD, there are currently no tools to…

Image and Video Processing · Electrical Eng. & Systems 2022-11-10 Zhuoyu Li , Camille Petri , James Howard , Graham Cole , Marta Varela

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality for the visualisation of microvasculature in vivo that has encountered broad adoption in retinal research. OCTA potential in the assessment of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Ylenia Giarratano , Eleonora Bianchi , Calum Gray , Andrew Morris , Tom MacGillivray , Baljean Dhillon , Miguel O. Bernabeu

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

Analyzing the morphological attributes of blood vessels plays a critical role in the computer-aided diagnosis of many cardiovascular and ophthalmologic diseases. Although being extensively studied, segmentation of blood vessels,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Yicheng Wu , Chengwei Pan , Shuqi Wang , Ming Zhang , Yong Xia , Yizhou Yu

Timely and affordable computer-aided diagnosis of retinal diseases is pivotal in precluding blindness. Accurate retinal vessel segmentation plays an important role in disease progression and diagnosis of such vision-threatening diseases. To…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Tariq M. Khan , Syed S. Naqvi , Antonio Robles-Kelly , Imran Razzak

In many medical imaging tasks, convolutional neural networks (CNNs) efficiently extract local features hierarchically. More recently, vision transformers (ViTs) have gained popularity, using self-attention mechanisms to capture global…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Kerol Djoumessi , Samuel Ofosu Mensah , Philipp Berens

Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han

The automatic segmentation of blood vessels in fundus images can help analyze the condition of retinal vasculature, which is crucial for identifying various systemic diseases like hypertension, diabetes, etc. Despite the success of Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Ashish Kumar , R. K. Agrawal , Leve Joseph

Nonunion is one of the challenges faced by orthopedics clinics for the technical difficulties and high costs in photographing interosseous capillaries. Segmenting vessels and filling capillaries are critical in understanding the obstacles…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Runpeng Hou , Ziyuan Ye , Chengyu Yang , Linhao Fu , Chao Liu , Quanying Liu

The accurate retinal vessel segmentation (RVS) is of great significance to assist doctors in the diagnosis of ophthalmology diseases and other systemic diseases. Manually designing a valid neural network architecture for retinal vessel…

Image and Video Processing · Electrical Eng. & Systems 2020-03-19 Zhun Fan , Jiahong Wei , Guijie Zhu , Jiajie Mo , Wenji Li