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Our research focuses on the critical field of early diagnosis of disease by examining retinal blood vessels in fundus images. While automatic segmentation of retinal blood vessels holds promise for early detection, accurate analysis remains…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Fatema Tuj Johora Faria , Mukaffi Bin Moin , Pronay Debnath , Asif Iftekher Fahim , Faisal Muhammad Shah

While recent advances in deep learning have significantly advanced the state of the art for vessel detection in color fundus (CF) images, the success for detecting vessels in fluorescein angiography (FA) has been stymied due to the lack of…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Li Ding , Mohammad H. Bawany , Ajay E. Kuriyan , Rajeev S. Ramchandran , Charles C. Wykoff , Gaurav Sharma

The retina is the only part of the human body in which blood vessels can be accessed non-invasively using imaging techniques such as digital fundus images (DFI). The spatial distribution of the retinal microvasculature may change with…

The caliber and configuration of retinal blood vessels serve as important biomarkers for various diseases and medical conditions. A thorough analysis of the retinal vasculature requires the segmentation of the blood vessels and their…

Image and Video Processing · Electrical Eng. & Systems 2025-03-13 José Morano , Guilherme Aresta , Hrvoje Bogunović

Retinal vessel segmentation is of great clinical significance for the diagnosis of many eye-related diseases, but it is still a formidable challenge due to the intricate vascular morphology. With the skillful characterization of the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-09 Zihong Sun , Hong Wang , Qi Xie , Yefeng Zheng , Deyu Meng

Vascular structures in the retina contain important information for the detection and analysis of ocular diseases, including age-related macular degeneration, diabetic retinopathy and glaucoma. Commonly used modalities in diagnosis of these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Erick O. Rodrigues , Aura Conci , Panos Liatsis

Among the research efforts to segment the retinal vasculature from fundus images, deep learning models consistently achieve superior performance. However, this data-driven approach is very sensitive to domain shifts. For fundus images, such…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Dewei Hu , Xing Yao , Jiacheng Wang , Yuankai K. Tao , Ipek Oguz

Accurate multi-class segmentation is a long-standing challenge in medical imaging, especially in scenarios where classes share strong similarity. Segmenting retinal blood vessels in retinal photographs is one such scenario, in which…

Image and Video Processing · Electrical Eng. & Systems 2021-12-10 Yukun Zhou , Moucheng Xu , Yipeng Hu , Hongxiang Lin , Joseph Jacob , Pearse A. Keane , Daniel C. Alexander

Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Hana Sebia , Thomas Guyet , Mickaël Pereira , Marco Valdebenito , Hugues Berry , Benjamin Vidal

Automatic segmentation of retinal blood vessels from fundus images plays an important role in the computer aided diagnosis of retinal diseases. The task of blood vessel segmentation is challenging due to the extreme variations in morphology…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Avijit Dasgupta , Sonam Singh

From diagnosing neovascular diseases to detecting white matter lesions, accurate tiny vessel segmentation in fundus images is critical. Promising results for accurate vessel segmentation have been known. However, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Suraj Mishra , Danny Z. Chen , X. Sharon Hu

Creating a dataset for training supervised machine learning algorithms can be a demanding task. This is especially true for medical image segmentation since one or more specialists are usually required for image annotation, and creating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Matheus Viana da Silva , Natália de Carvalho Santos , Julie Ouellette , Baptiste Lacoste , Cesar Henrique Comin

The change of retinal vasculature is an early sign of many vascular and systematic diseases, such as diabetes and hypertension. Different behaviors of retinal arterioles and venules form an important metric to measure the disease severity.…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Meng Li , Yan Zhang , Haicheng She , Jinqiong Zhou , Jia Jia , Danmei He , Li Zhang

Early identification of patients at risk of cardiovascular diseases (CVD) is crucial for effective preventive care, reducing healthcare burden, and improving patients' quality of life. This study demonstrates the potential of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Cynthia Maldonado-Garcia , Arezoo Zakeri , Alejandro F Frangi , Nishant Ravikumar

In this study, a supervised retina blood vessel segmentation process was performed on the green channel of the RGB image using artificial neural network (ANN). The green channel is preferred because the retinal vessel structures can be…

Image and Video Processing · Electrical Eng. & Systems 2020-01-17 Esra Kaya , İsmail Sarıtaş , Ilker Ali Ozkan

The retinal vascular condition is a reliable biomarker of several ophthalmologic and cardiovascular diseases, so automatic vessel segmentation may be crucial to diagnose and monitor them. In this paper, we propose a novel method that…

Image and Video Processing · Electrical Eng. & Systems 2018-12-21 Américo Oliveira , Sérgio Pereira , Carlos A. Silva

Retinal imaging is fast, non-invasive, and widely available, offering quantifiable structural and vascular signals for ophthalmic and systemic health assessment. This accessibility creates an opportunity to study how quantitative retinal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Zhonghua Wang , Lie Ju , Sijia Li , Wei Feng , Sijin Zhou , Ming Hu , Jianhao Xiong , Xiaoying Tang , Yifan Peng , Mingquan Lin , Yaodong Ding , Yong Zeng , Wenbin Wei , Li Dong , Zongyuan Ge

Purpose: Automatic and accurate segmentation of fundus vessel images has become an essential prerequisite for computer-aided diagnosis of ophthalmic diseases such as diabetes mellitus. The task of high-precision retinal vessel segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Xiang Li , Mingsi Liu , Lixin Duan

Our research is motivated by the urgent global issue of a large population affected by retinal diseases, which are evenly distributed but underserved by specialized medical expertise, particularly in non-urban areas. Our primary objective…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Deependra Singh , Saksham Agarwal , Subhankar Mishra

Vision impairment due to pathological damage of the retina can largely be prevented through periodic screening using fundus color imaging. However the challenge with large scale screening is the inability to exhaustively detect fine blood…

Machine Learning · Computer Science 2016-03-16 Debapriya Maji , Anirban Santara , Pabitra Mitra , Debdoot Sheet