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Deep learning models have emerged as a powerful tool for various medical applications. However, their success depends on large, high-quality datasets that are challenging to obtain due to privacy concerns and costly annotation. Generative…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Milad Yazdani , Yasamin Medghalchi , Pooria Ashrafian , Ilker Hacihaliloglu , Dena Shahriari

Diffusion and flow-based models have become the state of the art for generative AI across a wide range of data modalities, including images, videos, shapes, molecules, music, and more. This tutorial provides a self-contained introduction to…

Machine Learning · Computer Science 2026-03-19 Peter Holderrieth , Ezra Erives

Discrete diffusion or flow models could enable faster and more controllable sequence generation than autoregressive models. We show that na\"ive linear flow matching on the simplex is insufficient toward this goal since it suffers from…

Biomolecules · Quantitative Biology 2024-06-03 Hannes Stark , Bowen Jing , Chenyu Wang , Gabriele Corso , Bonnie Berger , Regina Barzilay , Tommi Jaakkola

We introduce NitroFusion, a fundamentally different approach to single-step diffusion that achieves high-quality generation through a dynamic adversarial framework. While one-step methods offer dramatic speed advantages, they typically…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Dar-Yen Chen , Hmrishav Bandyopadhyay , Kai Zou , Yi-Zhe Song

Diffusion models (DMs) are a powerful generative framework that have attracted significant attention in recent years. However, the high computational cost of training DMs limits their practical applications. In this paper, we start with a…

Machine Learning · Computer Science 2024-04-12 Tianshuo Xu , Peng Mi , Ruilin Wang , Yingcong Chen

Fast and accurate generation of molecular conformers is desired for downstream computational chemistry and drug discovery tasks. Currently, training and sampling state-of-the-art diffusion or flow-based models for conformer generation…

The slow iterative sampling nature remains a major bottleneck for the practical deployment of diffusion and flow-based generative models. While consistency models (CMs) represent a state-of-the-art distillation-based approach for efficient…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Linwei Dong , Ruoyu Guo , Ge Bai , Zehuan Yuan , Yawei Luo , Changqing Zou

Diffusion and flow matching models generate high-fidelity data by simulating paths defined by Ordinary or Stochastic Differential Equations (ODEs/SDEs), starting from a tractable prior distribution. The probability flow ODE formulation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Liangyu Yuan , Ruoyu Wang , Tong Zhao , Dingwen Fu , Mingkun Lei , Beier Zhu , Chi Zhang

Taming the generation outcome of state of the art Diffusion and Flow-Matching (FM) models without having to re-train a task-specific model unlocks a powerful tool for solving inverse problems, conditional generation, and controlled…

Machine Learning · Computer Science 2024-07-23 Heli Ben-Hamu , Omri Puny , Itai Gat , Brian Karrer , Uriel Singer , Yaron Lipman

Denoising-based models, such as diffusion and flow matching, have been a critical component of robotic manipulation for their strong distribution-fitting and scaling capacity. Concurrently, several works have demonstrated that simple…

Robotics · Computer Science 2025-11-25 Weixi Song , Zhetao Chen , Tao Xu , Xianchao Zeng , Xinyu Zhou , Lixin Yang , Donglin Wang , Cewu Lu , Yong-Lu Li

Recent advances in diffusion and flow-based generative models have demonstrated remarkable success in image restoration tasks, achieving superior perceptual quality compared to traditional deep learning approaches. However, these methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yuanzhi Zhu , Ruiqing Wang , Shilin Lu , Junnan Li , Hanshu Yan , Kai Zhang

Recent advances in inverse problem solving have increasingly adopted flow priors over diffusion models due to their ability to construct straight probability paths from noise to data, thereby enhancing efficiency in both training and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Hossein Askari , Yadan Luo , Hongfu Sun , Fred Roosta

Rectified flow and reflow procedures have significantly advanced fast generation by progressively straightening ordinary differential equation (ODE) flows. They operate under the assumption that image and noise pairs, known as couplings,…

Machine Learning · Computer Science 2024-11-04 Dogyun Park , Sojin Lee , Sihyeon Kim , Taehoon Lee , Youngjoon Hong , Hyunwoo J. Kim

Conventional physically based rendering (PBR) pipelines generate photorealistic images through computationally intensive light transport simulations. Although recent deep learning approaches leverage diffusion model priors with geometry…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Shenghao Zhang , Runtao Liu , Christopher Schroers , Yang Zhang

Diffusion-based imitation learning improves Behavioral Cloning (BC) on multi-modal decision-making, but comes at the cost of significantly slower inference due to the recursion in the diffusion process. It urges us to design efficient…

Machine Learning · Computer Science 2024-11-25 Xixi Hu , Bo Liu , Xingchao Liu , Qiang Liu

Generative models like Flow Matching have achieved state-of-the-art performance but are often hindered by a computationally expensive iterative sampling process. To address this, recent work has focused on few-step or one-step generation by…

Machine Learning · Computer Science 2025-07-24 Yi Guo , Wei Wang , Zhihang Yuan , Rong Cao , Kuan Chen , Zhengyang Chen , Yuanyuan Huo , Yang Zhang , Yuping Wang , Shouda Liu , Yuxuan Wang

Diffusion models generate high-quality images but require dozens of forward passes. We introduce Distribution Matching Distillation (DMD), a procedure to transform a diffusion model into a one-step image generator with minimal impact on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Tianwei Yin , Michaël Gharbi , Richard Zhang , Eli Shechtman , Fredo Durand , William T. Freeman , Taesung Park

Conditional flow matching (CFM) stands out as an efficient, simulation-free approach for training flow-based generative models, achieving remarkable performance for data generation. However, CFM is insufficient to ensure accuracy in…

Machine Learning · Computer Science 2026-02-03 Yuhao Huang , Taos Transue , Shih-Hsin Wang , William Feldman , Hong Zhang , Bao Wang

Diffusion-based or flow-based models have achieved significant progress in video synthesis but require multiple iterative sampling steps, which incurs substantial computational overhead. While many distillation methods that are solely based…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Yanxiao Sun , Jiafu Wu , Yun Cao , Chengming Xu , Yabiao Wang , Weijian Cao , Donghao Luo , Chengjie Wang , Yanwei Fu

Generative models have excelled in audio tasks using approaches such as language models, diffusion, and flow matching. However, existing generative approaches for speech enhancement (SE) face notable challenges: language model-based methods…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-28 Ziqian Wang , Zikai Liu , Xinfa Zhu , Yike Zhu , Mingshuai Liu , Jun Chen , Longshuai Xiao , Chao Weng , Lei Xie
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