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Identifying novel hypotheses is essential to scientific research, yet this process risks being overwhelmed by the sheer volume and complexity of available information. Existing automated methods often struggle to generate novel and…

Multi-Agent Path Finding (MAPF) is a fundamental problem in robotics, requiring the computation of collision-free paths for multiple agents moving from their respective start to goal positions. Coordinating multiple agents in a shared…

Robotics · Computer Science 2024-12-25 Jinhao Liang , Jacob K. Christopher , Sven Koenig , Ferdinando Fioretto

Objective: Radiation therapy treatment planning is a time-consuming, iterative process with potentially high inter-planner variability. Fully automated treatment planning processes could reduce a planner's active treatment planning time and…

Medical Physics · Physics 2021-02-09 Charles Huang , Yong Yang , Neil Panjwani , Stephen Boyd , Lei Xing

For Artificial Intelligence to have a greater impact in biology and medicine, it is crucial that recommendations are both accurate and transparent. In other domains, a neurosymbolic approach of multi-hop reasoning on knowledge graphs has…

Machine Learning · Computer Science 2022-10-10 Gavin Edwards , Sebastian Nilsson , Benedek Rozemberczki , Eliseo Papa

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Medical Dialogue Systems aim to provide automated healthcare support through patient-agent conversations. Previous efforts typically regard patients as ideal users -- one who accurately and consistently reports their health conditions.…

Computation and Language · Computer Science 2024-12-25 Lang Qin , Yao Zhang , Hongru Liang , Adam Jatowt , Zhenglu Yang

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

Applications · Statistics 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

The recent explosive growth in Deep Neural Networks applications raises concerns about the black-box usage of such models, with limited trasparency and trustworthiness in high-stakes domains, which have been crystallized as regulatory…

Machine Learning · Computer Science 2025-12-23 Lorenzo Capelli , Leandro de Souza Rosa , Gianluca Setti , Mauro Mangia , Riccardo Rovatti

Pre-trained on extensive text and image corpora, current Multi-Modal Large Language Models (MLLM) have shown strong capabilities in general visual reasoning tasks. However, their performance is still lacking in physical domains that require…

Artificial Intelligence · Computer Science 2025-07-04 Erle Zhu , Yadi Liu , Zhe Zhang , Xujun Li , Jin Zhou , Xinjie Yu , Minlie Huang , Hongning Wang

The seamless integration of physical and digital environments in Cyber-Physical Systems(CPS), particularly within Industry 4.0, presents significant challenges stemming from system heterogeneity and complexity. Traditional approaches often…

Multiagent Systems · Computer Science 2025-10-14 Walid Abdela

This paper is concerned with a recently developed paradigm for population-based optimization, termed particle filter optimization (PFO). This paradigm is attractive in terms of coherence in theory and easiness in mathematical analysis and…

Machine Learning · Statistics 2018-11-26 Bin Liu , Yaochu Jin

Topological materials occupy a frontier in condensed-matter physics thanks to their remarkable electronic and quantum properties, yet their cross-scale design remains bottlenecked by inefficient discovery workflows. Here, we introduce…

Materials Science · Physics 2025-07-08 Baohua Zhang , Xin Li , Huangchao Xu , Zhong Jin , Quansheng Wu , Ce Li

Throughout application domains, we now rely extensively on algorithmic systems to engage with ever-expanding datasets of information. Despite their benefits, these systems are often complex (comprising of many intricate tools, e.g.,…

Computers and Society · Computer Science 2025-10-21 Stefania Ionescu , Robin Forsberg , Elsa Lichtenegger , Salima Jaoua , Kshitijaa Jaglan , Florian Dorfler , Aniko Hannak

This study sought to (1) expand our existing Urban Population Health Observatory (UPHO) system by incorporating a semantics layer; (2) cohesively employ machine learning and semantic/logical inference to provide measurable evidence and…

Artificial Intelligence · Computer Science 2022-08-09 Whitney S Brakefield , Nariman Ammar , Arash Shaban-Nejad

Introduction: Nottingham grading system is a major prognostic factor for invasive breast carcinoma (IBC). Its determination requires the evaluation of the mitotic score (MS) which is subject to low intra- and inter-observer reproducibility.…

Real-world multimodal applications often require any-to-any capabilities, enabling both understanding and generation across modalities including text, image, audio, and video. However, integrating the strengths of autoregressive language…

Machine Learning · Computer Science 2025-08-15 Jiulin Li , Ping Huang , Yexin Li , Shuo Chen , Juewen Hu , Ye Tian

We present OpenICS, an image compressive sensing toolbox that includes multiple image compressive sensing and reconstruction algorithms proposed in the past decade. Due to the lack of standardization in the implementation and evaluation of…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Jonathan Zhao , Matthew Westerham , Mark Lakatos-Toth , Zhikang Zhang , Avi Moskoff , Fengbo Ren

Biomedical knowledge graphs (KGs) encode vast, heterogeneous information spanning literature, genes, pathways, drugs, diseases, and clinical trials, but leveraging them collectively for scientific discovery remains difficult. Their…

Information Retrieval · Computer Science 2026-01-21 Zifeng Wang , Zheng Chen , Ziwei Yang , Xuan Wang , Qiao Jin , Yifan Peng , Zhiyong Lu , Jimeng Sun

Multi-agent systems (MASs) have emerged as a promising paradigm for automated code generation, demonstrating impressive performance on established benchmarks. Despite their prosperous development, the fundamental mechanisms underlying their…

Software Engineering · Computer Science 2026-02-02 Zongyi Lyu , Songqiang Chen , Zhenlan Ji , Liwen Wang , Shuai Wang , Daoyuan Wu , Wenxuan Wang , Shing-Chi Cheung