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The minimum energy path (MEP) is the most probable transition path that connects two equilibrium states of a potential energy landscape. It has been widely used to study transition mechanisms as well as transition rates in the fields of…

Numerical Analysis · Mathematics 2022-07-01 Xuanyu Liu , Huajie Chen , Christoph Ortner

Stochastic electronic structure theories, e.g., Quantum Monte Carlo methods, enable highly accurate total energy calculations which in principle can be used to construct highly accurate potential energy surfaces. However, their stochastic…

Quantum mechanical methods like Density Functional Theory (DFT) are used with great success alongside efficient search algorithms for studying kinetics of reactive systems. However, DFT is prohibitively expensive for large scale…

Computational Physics · Physics 2022-09-02 Mathias Schreiner , Arghya Bhowmik , Tejs Vegge , Peter Bjørn Jørgensen , Ole Winther

The modeling of solid-state transformations, such as polymorphic transitions and chemical reactions in molecular crystals, is vital for many applications including drug design or the development of new synthesis methods. However, a…

Chemical Physics · Physics 2025-06-17 Natalia Goncharova , Johannes Hoja

We use the nudged elastic band method from computational chemistry to analyze high-dimensional data. Our approach is inspired by Morse theory, and as output we produce an increasing sequence of small cell complexes modeling the dense…

General Topology · Mathematics 2020-07-14 Henry Adams , Atanas Atanasov , Gunnar Carlsson

Recently, neural architecture search (NAS) has been applied to automate the design of neural networks in real-world applications. A large number of algorithms have been developed to improve the search cost or the performance of the final…

Machine Learning · Computer Science 2022-06-20 Yao Shu , Yizhou Chen , Zhongxiang Dai , Bryan Kian Hsiang Low

Fragmentation methods such as the many-body expansion (MBE) are a common strategy to model large systems by partitioning energies into a hierarchy of decreasingly significant contributions. The number of fragments required for chemical…

Chemical Physics · Physics 2017-09-13 Kun Yao , John E. Herr , John Parkhill

Popular methods for identifying transition paths between energy minima, such as the nudged elastic band and string methods, typically do not incorporate potential energy curvature information, leading to slow relaxation to the minimum…

Computational Physics · Physics 2019-03-11 Stela Makri , Christoph Ortner , James R. Kermode

We present the Branch-and-Bound Performance Estimation Programming (BnB-PEP), a unified methodology for constructing optimal first-order methods for convex and nonconvex optimization. BnB-PEP poses the problem of finding the optimal…

Optimization and Control · Mathematics 2023-06-09 Shuvomoy Das Gupta , Bart P. G. Van Parys , Ernest K. Ryu

Computational chemistry has become an important tool to predict and understand molecular properties and reactions. Even though recent years have seen a significant growth in new algorithms and computational methods that speed up quantum…

Chemical Physics · Physics 2023-07-26 Albert Thie , Maximilian F. S. J. Menger , Shirin Faraji

Neuro-encoded expression programming(NEEP) that aims to offer a novel continuous representation of combinatorial encoding for genetic programming methods is proposed in this paper. Genetic programming with linear representation uses…

Neural and Evolutionary Computing · Computer Science 2021-04-12 Aftab Anjum , Fengyang Sun , Lin Wang , Jeff Orchard

Differential Networks (DNs), tools that encapsulate interactions within intricate systems, are brought under the Bayesian lens in this research. A novel na{\i}ve Bayesian adaptive graphical elastic net (BAE) prior is introduced to estimate…

Methodology · Statistics 2023-06-27 J. Smith , A. Bekker , M. Arashi

Diagnosing the internal state of Li-ion batteries is critical for battery research, operation of real-world systems, and prognostic evaluation of remaining lifetime. By using physics-based models to perform probabilistic parameter…

Data Analysis, Statistics and Probability · Physics 2026-04-06 Malik Hassanaly , Corey R. Randall , Peter J. Weddle , Paul J. Gasper , Conlain Kelly , Tanvir R. Tanim , Kandler Smith

Single-cell sequencing is revolutionizing biology by enabling detailed investigations of cell-state transitions. Many biological processes unfold along continuous trajectories, yet it remains challenging to extract smooth, low-dimensional…

Machine Learning · Statistics 2025-06-30 Rong Ma , Xi Li , Jingyuan Hu , Bin Yu

Solid-state electrolytes are essential in the development of all-solid-state batteries. While density functional theory (DFT)-based nudged elastic band (NEB) and ab initio molecular dynamics (AIMD) methods provide fundamental insights on…

Materials Science · Physics 2025-07-04 Jingchen Lian , Xiao Fu , Xuhe Gong , Ruijuan Xiao , Hong Li

We study the problem of computing constrained shortest paths for battery electric vehicles. Since battery capacities are limited, fastest routes are often infeasible. Instead, users are interested in fast routes on which the energy…

Data Structures and Algorithms · Computer Science 2020-11-23 Moritz Baum , Julian Dibbelt , Dorothea Wagner , Tobias Zündorf

Ultrafast electron diffraction using MeV energy beams(MeV-UED) has enabled unprecedented scientific opportunities in the study of ultrafast structural dynamics in a variety of gas, liquid and solid state systems. Broad scientific…

The embedded atom method (EAM) is one of the most widely used many-body, short-range potentials in molecular dynamics simulations, particularly for metallic systems. To enhance the efficiency of calculating these short-range interactions,…

Materials Science · Physics 2025-03-25 Jieqiong Zhang , Jizu Huang , Zihao Yang

The Chain-of-states(CoS) methods like nudge elastic band(NEB) method can be used to determine the minimum energy path (MEP) and transition state (TS) between two end local minima. However, the CoS methods are inefficient for difficult cases…

Chemical Physics · Physics 2019-04-16 Sky , Zhang , Hai Xiao , Jun Li

Binary Neural Networks (BNNs), which constrain both weights and activations to binary values, offer substantial reductions in computational complexity, memory footprint, and energy consumption. These advantages make them particularly well…

Machine Learning · Computer Science 2026-02-18 Luca Colombo , Fabrizio Pittorino , Daniele Zambon , Carlo Baldassi , Manuel Roveri , Cesare Alippi