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Diffeomorphic deformable multi-modal image registration is a challenging task which aims to bring images acquired by different modalities to the same coordinate space and at the same time to preserve the topology and the invertibility of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Vasiliki Sideri-Lampretsa , Georgios Kaissis , Daniel Rueckert

Regularization strategies in medical image registration often take a one-size-fits-all approach by imposing uniform constraints across the entire image domain. Yet biological structures are anything but regular. Lacking structural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Ziad Kheil , Soleakhena Ken , Laurent Risser

This paper presents a review of deep learning (DL) based medical image registration methods. We summarized the latest developments and applications of DL-based registration methods in the medical field. These methods were classified into…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Yabo Fu , Yang Lei , Tonghe Wang , Walter J. Curran , Tian Liu , Xiaofeng Yang

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Effective representation of Regions of Interest (ROI) and independent alignment of these ROIs can significantly enhance the performance of deformable medical image registration (DMIR). However, current learning-based DMIR methods have…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Xinke Ma , Yongsheng Pan , Qingjie Zeng , Mengkang Lu , Bolysbek Murat Yerzhanuly , Bazargul Matkerim , Yong Xia

Learning non-rigid registration in an end-to-end manner is challenging due to the inherent high degrees of freedom and the lack of labeled training data. In this paper, we resolve these two challenges simultaneously. First, we propose to…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Wanquan Feng , Juyong Zhang , Hongrui Cai , Haofei Xu , Junhui Hou , Hujun Bao

Multimodal image registration between diffusion MRI (dMRI) and T1-weighted (T1w) MRI images is a critical step for aligning diffusion-weighted imaging (DWI) data with structural anatomical space. Traditional registration methods often…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Xiaofan Wang , Junyi Wang , Yuqian Chen , Lauren J. O' Donnell , Fan Zhang

Recently, Artificial Intelligence (AI)-based algorithms have revolutionized the medical image segmentation processes. Thus, the precise segmentation of organs and their lesions may contribute to an efficient diagnostics process and a more…

Neurons and Cognition · Quantitative Biology 2024-03-21 Zofia Rudnicka , Janusz Szczepanski , Agnieszka Pregowska

Multi-contrast magnetic resonance (MR) image registration is useful in the clinic to achieve fast and accurate imaging-based disease diagnosis and treatment planning. Nevertheless, the efficiency and performance of the existing registration…

Image and Video Processing · Electrical Eng. & Systems 2021-02-17 Weijian Huang , Hao Yang , Xinfeng Liu , Cheng Li , Ian Zhang , Rongpin Wang , Hairong Zheng , Shanshan Wang

Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image…

Image and Video Processing · Electrical Eng. & Systems 2020-09-22 Zhe Xu , Jie Luo , Jiangpeng Yan , Ritvik Pulya , Xiu Li , William Wells , Jayender Jagadeesan

Reliably and physically accurately transferring information between images through deformable image registration with large anatomical differences is an open challenge in medical image analysis. Most existing methods have two key…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Georgios Andreadis , Peter A. N. Bosman , Tanja Alderliesten

Robust and accurate 2D/3D registration, which aligns preoperative models with intraoperative images of the same anatomy, is crucial for successful interventional navigation. To mitigate the challenge of a limited field of view in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Yuxin Cui , Rui Song , Yibin Li , Max Q. -H. Meng , Zhe Min

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Xiang Chen , Nishant Ravikumar , Yan Xia , Alejandro F Frangi

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Ameneh Sheikhjafari , Michelle Noga , Kumaradevan Punithakumar , Nilanjan Ray

In medicine, image registration is vital in image-guided interventions and other clinical applications. However, it is a difficult subject to be addressed which by the advent of machine learning, there have been considerable progress in…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Samaneh Abbasi , Meysam Tavakoli , Hamid Reza Boveiri , Mohammad Amin Mosleh Shirazi , Raouf Khayami , Hedieh Khorasani , Reza Javidan , Alireza Mehdizadeh

Deep learning has revolutionized medical image registration by achieving unprecedented speeds, yet its clinical application is hindered by a limited ability to generalize beyond the training domain, a critical weakness given the typically…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Fengting Zhang , Yue He , Qinghao Liu , Yaonan Wang , Xiang Chen , Hang Zhang

Accurate deformable 4-dimensional (4D) (3-dimensional in space and time) medical images registration is essential in a variety of medical applications. Deep learning-based methods have recently gained popularity in this area for the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 Yunlu Zhang , Xue Wu , H. Michael Gach , Harold Li , Deshan Yang

Deep learning has revolutionized image registration by its ability to handle diverse tasks while achieving significant speed advantages over conventional approaches. Current approaches, however, often employ globally uniform smoothness…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Xiang Chen , Fengting Zhang , Qinghao Liu , Min Liu , Kun Wu , Yaonan Wang , Hang Zhang

High-fidelity biomechanical models usually involve the mechanical characterization of biological tissues using experimental methods based on optical measurements. In most experiments, strains are evaluated based on displacements of a few…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Ondřej Lisický , Stéphane Avril , Bastien Eydan , Baptiste Pierrat , Jiří Burša
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