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Deep neural networks are playing an important role in state-of-the-art visual recognition. To represent high-level visual concepts, modern networks are equipped with large convolutional layers, which use a large number of filters and…

Computer Vision and Pattern Recognition · Computer Science 2017-03-06 Yan Wang , Lingxi Xie , Ya Zhang , Wenjun Zhang , Alan Yuille

Cross-modal retrieval (CMR) typically involves learning common representations to directly measure similarities between multimodal samples. Most existing CMR methods commonly assume multimodal samples in pairs and employ joint training to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Ruitao Pu , Yang Qin , Dezhong Peng , Xiaomin Song , Huiming Zheng

Graph representation learning has emerged as a powerful tool for preserving graph topology when mapping nodes to vector representations, enabling various downstream tasks such as node classification and community detection. However, most…

Machine Learning · Computer Science 2025-03-21 Kaizhe Fan , Quanjun Li

Molecular representation learning contributes to multiple downstream tasks such as molecular property prediction and drug design. To properly represent molecules, graph contrastive learning is a promising paradigm as it utilizes…

Machine Learning · Computer Science 2022-03-14 Yin Fang , Qiang Zhang , Haihong Yang , Xiang Zhuang , Shumin Deng , Wen Zhang , Ming Qin , Zhuo Chen , Xiaohui Fan , Huajun Chen

The primary objective of Optical Chemical Structure Recognition is to identify chemical structure images into corresponding markup sequences. However, the complex two-dimensional structures of molecules, particularly those with rings and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Qikai Chang , Mingjun Chen , Changpeng Pi , Pengfei Hu , Zhenrong Zhang , Jiefeng Ma , Jun Du , Baocai Yin , Jinshui Hu

Class-incremental learning (CIL) in medical image-guided diagnosis requires retaining prior diagnostic knowledge while adapting to newly emerging disease categories, which is critical for scalable clinical deployment. This problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Xinyao Wu , Zhe Xu , Cheng Chen , Jiawei Ma , Yefeng Zheng , Raymond Kai-yu Tong

Molecular representation learning (MRL) is a key step to build the connection between machine learning and chemical science. In particular, it encodes molecules as numerical vectors preserving the molecular structures and features, on top…

Quantitative Methods · Quantitative Biology 2023-11-30 Zhichun Guo , Kehan Guo , Bozhao Nan , Yijun Tian , Roshni G. Iyer , Yihong Ma , Olaf Wiest , Xiangliang Zhang , Wei Wang , Chuxu Zhang , Nitesh V. Chawla

Despite the success of deep learning methods in quantum chemistry, their representational capacity is most often confined to neutral, closed-shell molecules. However, real-world chemical systems often exhibit complex characteristics,…

Self-supervised learning (SSL) has recently achieved great success in mining the user-item interactions for collaborative filtering. As a major paradigm, contrastive learning (CL) based SSL helps address data sparsity in Web platforms by…

Information Retrieval · Computer Science 2024-02-20 Dan Zhang , Yangliao Geng , Wenwen Gong , Zhongang Qi , Zhiyu Chen , Xing Tang , Ying Shan , Yuxiao Dong , Jie Tang

High dimensional data analysis for exploration and discovery includes three fundamental tasks: dimensionality reduction, clustering, and visualization. When the three associated tasks are done separately, as is often the case thus far,…

Machine Learning · Computer Science 2020-12-02 Stan Z. Li , Lirong Wu , Zelin Zang

Virtual screening plays a critical role in modern drug discovery by enabling the identification of promising candidate molecules for experimental validation. Traditional machine learning methods such, as Support Vector Machines (SVM) and…

Machine Learning · Computer Science 2025-04-29 Radia Berreziga , Mohammed Brahimi , Khairedine Kraim , Hamid Azzoune

Automatic and precise medical image segmentation (MIS) is of vital importance for clinical diagnosis and analysis. Current MIS methods mainly rely on the convolutional neural network (CNN) or self-attention mechanism (Transformer) for…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Lanhu Wu , Miao Zhang , Yongri Piao , Zhenyan Yao , Weibing Sun , Feng Tian , Huchuan Lu

Recent years have seen a rapid growth of utilizing graph neural networks (GNNs) in the biomedical domain for tackling drug-related problems. However, like any other deep architectures, GNNs are data hungry. While requiring labels in real…

Biological Physics · Physics 2022-05-03 Mengying Sun , Jing Xing , Huijun Wang , Bin Chen , Jiayu Zhou

Fine-grained Vision-Language Pre-training (FVLP) demonstrates significant potential in 3D medical image understanding by aligning anatomy-level visual representations with corresponding textual descriptions. However, existing FVLP paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Hanwen Zhang , Yao Liu , Die Dai , Jiaye Yang , Qiao Liu , Yutong Xie , Peng Wang

One of the well-known challenges in computer vision tasks is the visual diversity of images, which could result in an agreement or disagreement between the learned knowledge and the visual content exhibited by the current observation. In…

Machine Learning · Computer Science 2020-01-03 Yan Luo , Yongkang Wong , Mohan S. Kankanhalli , Qi Zhao

The prevailing graph neural network models have achieved significant progress in graph representation learning. However, in this paper, we uncover an ever-overlooked phenomenon: the pre-trained graph representation learning model tested…

Machine Learning · Computer Science 2023-02-14 Hang Gao , Jiangmeng Li , Wenwen Qiang , Lingyu Si , Bing Xu , Changwen Zheng , Fuchun Sun

In this work, we study the continual semantic segmentation problem, where the deep neural networks are required to incorporate new classes continually without catastrophic forgetting. We propose to use a structural re-parameterization…

Computer Vision and Pattern Recognition · Computer Science 2022-03-11 Chang-Bin Zhang , Jia-Wen Xiao , Xialei Liu , Ying-Cong Chen , Ming-Ming Cheng

Graph contrastive learning (GCL) has achieved remarkable success by following the computer vision paradigm of preserving absolute similarity between augmented views. However, this approach faces fundamental challenges in graphs due to their…

Machine Learning · Computer Science 2025-05-13 Zhiyuan Ning , Pengfei Wang , Ziyue Qiao , Pengyang Wang , Yuanchun Zhou

Recently, image-text matching has attracted more and more attention from academia and industry, which is fundamental to understanding the latent correspondence across visual and textual modalities. However, most existing methods implicitly…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Yang Qin , Yuan Sun , Dezhong Peng , Joey Tianyi Zhou , Xi Peng , Peng Hu

A persistent structural weakness in deep clustering is the disconnect between feature learning and cluster assignment. Most architectures invoke an external clustering step, typically k-means, to produce pseudo-labels that guide training,…

Machine Learning · Computer Science 2026-04-03 Giansalvo Cirrincione
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