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Species tree reconstruction is complicated by effects of Incomplete Lineage Sorting (ILS), commonly modeled by the multi-species coalescent model. While there has been substantial progress in developing methods that estimate a species tree…

Quantitative Methods · Quantitative Biology 2016-05-10 Erfan Sayyari , Siavash Mirarab

Identification of taxa can significantly be assisted by statistical classification based on trait measurements in two major ways; either individually or by phylogenetic (clustering) methods. In this paper we present a general Bayesian…

Applications · Statistics 2021-09-17 Måns Karlsson , Ola Hössjer

We present a multi-fidelity method for uncertainty quantification of parameter estimates in complex systems, leveraging generative models trained to sample the target conditional distribution. In the Bayesian inference setting, traditional…

Machine Learning · Computer Science 2025-04-03 Caroline Tatsuoka , Minglei Yang , Dongbin Xiu , Guannan Zhang

Refining one's hypotheses in the light of data is a common scientific practice; however, the dependency on the data introduces selection bias and can lead to specious statistical analysis. An approach for addressing this is via conditioning…

Machine Learning · Computer Science 2020-03-03 Jen Ning Lim , Makoto Yamada , Wittawat Jitkrittum , Yoshikazu Terada , Shigeyuki Matsui , Hidetoshi Shimodaira

Central to rough path theory is the signature transform of a path, an infinite series of tensors given by the iterated integrals of the underlying path. The signature poses an effective way to capture sequentially ordered information,…

Numerical Analysis · Mathematics 2024-12-18 Daniil Shmelev , Cristopher Salvi

Many astronomical surveys prompt follow-up observations, but the decision process through which candidates are selected for follow-up can be difficult to model. This poses a challenge when inferring properties of the intrinsic population of…

Instrumentation and Methods for Astrophysics · Physics 2026-05-08 Reed Essick , Amanda M. Farah

Inferring the structure of gene regulatory networks (GRN) from gene expression data has many applications, from the elucidation of complex biological processes to the identification of potential drug targets. It is however a notoriously…

Machine Learning · Statistics 2012-05-08 Anne-Claire Haury , Fantine Mordelet , Paola Vera-Licona , Jean-Philippe Vert

The complex correlation structure of a collection of orthologous DNA sequences is uniquely captured by the "ancestral recombination graph" (ARG), a complete record of coalescence and recombination events in the history of the sample.…

Populations and Evolution · Quantitative Biology 2013-12-04 Matthew D. Rasmussen , Melissa J. Hubisz , Ilan Gronau , Adam Siepel

A central statistical problem in population genetics is to infer evolutionary and biological parameters such as the strength of natural selection and allele age from DNA samples extracted from a contemporary population. That all samples…

Populations and Evolution · Quantitative Biology 2025-02-19 Jaromir Sant , Paul A. Jenkins , Jere Koskela , Dario Spano

Analysing non-Gaussian spatial-temporal data requires introducing spatial as well as temporal dependence in generalised linear models through the link function of an exponential family distribution. Unlike in Gaussian likelihoods, inference…

Methodology · Statistics 2025-12-29 Soumyakanti Pan , Lu Zhang , Jonathan R. Bradley , Sudipto Banerjee

The 'signature method' refers to a collection of feature extraction techniques for multivariate time series, derived from the theory of controlled differential equations. There is a great deal of flexibility as to how this method can be…

Machine Learning · Computer Science 2021-02-09 James Morrill , Adeline Fermanian , Patrick Kidger , Terry Lyons

Kernel Bayesian inference is a principled approach to nonparametric inference in probabilistic graphical models, where probabilistic relationships between variables are learned from data in a nonparametric manner. Various algorithms of…

Machine Learning · Statistics 2019-04-18 Yu Nishiyama , Motonobu Kanagawa , Arthur Gretton , Kenji Fukumizu

This paper presents a novel method for statistical inference in high-dimensional binary models with unspecified structure, where we leverage a (potentially misspecified) sparsity-constrained working generalized linear model (GLM) to…

Methodology · Statistics 2025-10-03 Xiaotian Hou , Peng Wang , Minge Xie , Linjun Zhang

Inspired by the combination of feedforward and iterative computations in the virtual cortex, and taking advantage of the ability of denoising autoencoders to estimate the score of a joint distribution, we propose a novel approach to…

Computer Vision and Pattern Recognition · Computer Science 2017-08-22 Adriana Romero , Michal Drozdzal , Akram Erraqabi , Simon Jégou , Yoshua Bengio

Computer Vision practitioners must thoroughly understand their model's performance, but conditional evaluation is complex and error-prone. In biometric verification, model performance over continuous covariates---real-number attributes of…

Machine Learning · Computer Science 2020-09-22 Mel McCurrie , Hamish Nicholson , Walter J. Scheirer , Samuel Anthony

This paper utilizes the modified signed log-likelihood ratio method for the problem of inference about the common coefficient of variation in several independent normal populations. This method is applicable for both the problem of…

Computation · Statistics 2017-07-14 Mohmammad Reza Kazemi , Ali Akbar Jafari

Here we present the first genome wide statistical test for recessive selection. This test uses explicitly non-equilibrium demographic differences between populations to infer the mode of selection. By analyzing the transient response to a…

Populations and Evolution · Quantitative Biology 2014-03-24 Daniel J. Balick , Ron Do , David Reich , Shamil R. Sunyaev

Background: Predictive, stable and interpretable gene signatures are generally seen as an important step towards a better personalized medicine. During the last decade various methods have been proposed for that purpose. However, one…

Genomics · Quantitative Biology 2013-05-28 Yupeng Cun , Holger Fröhlich

In this paper we introduce a novel method for linear system identification with quantized output data. We model the impulse response as a zero-mean Gaussian process whose covariance (kernel) is given by the recently proposed stable spline…

Systems and Control · Computer Science 2015-04-28 Giulio Bottegal , Gianluigi Pillonetto , Håkan Hjalmarsson

We propose a score-based generative algorithm for sampling from power-scaled priors and likelihoods within the Bayesian inference framework. Our algorithm enables flexible control over prior-likelihood influence without requiring retraining…

Machine Learning · Computer Science 2026-04-03 Huseyin Tuna Erdinc , Yunlin Zeng , Abhinav Prakash Gahlot , Felix J. Herrmann