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When dealing with the problem of simultaneously testing a large number of null hypotheses, a natural testing strategy is to first reduce the number of tested hypotheses by some selection (screening or filtering) process, and then to…

Methodology · Statistics 2017-03-21 Wenge Guo , Joseph P. Romano

In large scale multiple testing problems, a two-class empirical Bayes approach can be used to control the false discovery rate (Fdr) for the entire array of hypotheses under study. A sample splitting step is incorporated to modify that…

Computation · Statistics 2019-12-13 Paramita Chakraborty , Chong Ma , John Grego , James Lynch

We employ optimal control theory to study the problem of estimating the probability density function from a data set originating from an unknown probability distribution. The original variational problem is reformulated as a multi-stage…

Optimization and Control · Mathematics 2025-10-02 Markus Hegland , C. Yalçın Kaya

This work develops a novel power control framework for energy-efficient power control in wireless networks. The proposed method is a new branch-and-bound procedure based on problem-specific bounds for energy-efficiency maximization that…

Information Theory · Computer Science 2020-07-13 Bho Matthiesen , Alessio Zappone , Karl-L. Besser , Eduard A. Jorswieck , Merouane Debbah

In this paper we consider a general, challenging distributed optimization set-up arising in several important network control applications. Agents of a network want to minimize the sum of local cost functions, each one depending on a local…

Systems and Control · Computer Science 2018-06-15 Ivano Notarnicola , Giuseppe Notarstefano

In this paper, we investigate sequential power allocation over fast varying channels for mission-critical applications, aiming to minimize the expected sum power while guaranteeing the transmission success probability. In particular, a…

Information Theory · Computer Science 2023-06-09 Chongtao Guo , Zhengchao Li , Le Liang , Geoffrey Ye Li

Controlling the false discovery rate (FDR) is a powerful approach to multiple testing. In many applications, the tested hypotheses have an inherent hierarchical structure. In this paper, we focus on the fixed sequence structure where the…

Methodology · Statistics 2016-11-11 Gavin Lynch , Wenge Guo , Sanat K. Sarkar , Helmut Finner

Many researchers in artificial intelligence are beginning to explore the use of soft constraints to express a set of (possibly conflicting) problem requirements. A soft constraint is a function defined on a collection of variables which…

Artificial Intelligence · Computer Science 2011-07-04 D. Cohen , M. Cooper , P. Jeavons , A. Krokhin

We develop a dynamic version of the primal-dual method for optimization problems, and apply it to obtain the following results. (1) For the dynamic set-cover problem, we maintain an $O(f^2)$-approximately optimal solution in $O(f \cdot \log…

Data Structures and Algorithms · Computer Science 2016-04-20 Sayan Bhattacharya , Monika Henzinger , Giuseppe F. Italiano

In high dimensional variable selection problems, statisticians often seek to design multiple testing procedures that control the False Discovery Rate (FDR), while concurrently identifying a greater number of relevant variables. Model-X…

Statistics Theory · Mathematics 2023-07-25 Taejoo Ahn , Licong Lin , Song Mei

Hypothesis testing in the linear regression model is a fundamental statistical problem. We consider linear regression in the high-dimensional regime where the number of parameters exceeds the number of samples ($p> n$). In order to make…

Statistics Theory · Mathematics 2019-09-24 Adel Javanmard , Jason D. Lee

The primal problem of multinomial likelihood maximization restricted to a convex closed subset of the probability simplex is studied. Contrary to widely held belief, a solution of this problem may assign a positive mass to an outcome with…

Statistics Theory · Mathematics 2017-06-21 Marian Grendár , Vladimír Špitalský

Finding the largest cardinality feasible subset of an infeasible set of linear constraints is the Maximum Feasible Subsystem problem (MAX FS). Solving this problem is crucial in a wide range of applications such as machine learning and…

Optimization and Control · Mathematics 2021-02-12 Fereshteh Fakhar Firouzeh , John W. Chinneck , Sreeraman Rajan

The key limitation of the verification performance lies in the ability of error detection. With this intuition we designed several variants of pessimistic verification, which are simple workflows that could significantly improve the…

Artificial Intelligence · Computer Science 2025-11-27 Yanxing Huang , Zihan Tang , Zejin Lin , Peng Li , Yang Liu

We propose new, optimal methods for analyzing randomized trials, when it is suspected that treatment effects may differ in two predefined subpopulations. Such sub-populations could be defined by a biomarker or risk factor measured at…

Methodology · Statistics 2016-11-26 Michael Rosenblum , Han Liu , and En-Hsu Yen

An important issue for many economic experiments is how the experimenter can ensure sufficient power for rejecting one or more hypotheses. Here, we apply methods developed mainly within the area of clinical trials for testing multiple…

Methodology · Statistics 2021-08-06 Sebastian Jobjörnsson , Henning Schaak , Oliver Mußhoff , Tim Friede

Recent research has shown that optimization proxies can be trained to high fidelity, achieving average optimality gaps under 1% for large-scale problems. However, worst-case analyses show that there exist in-distribution queries that result…

Machine Learning · Computer Science 2026-04-14 Michael Klamkin , Mathieu Tanneau , Pascal Van Hentenryck

Factor analysis is over a century old, but it is still problematic to choose the number of factors for a given data set. The scree test is popular but subjective. The best performing objective methods are recommended on the basis of…

Methodology · Statistics 2015-11-12 A. B. Owen , J. Wang

In small sample studies with binary outcome data, use of a normal approximation for hypothesis testing can lead to substantial inflation of the type-I error-rate. Consequently, exact statistical methods are necessitated, and accordingly,…

Methodology · Statistics 2017-11-29 Michael Grayling , Adrian Mander , James Wason

In many large scale multiple testing applications, the hypotheses often have a known graphical structure, such as gene ontology in gene expression data. Exploiting this graphical structure in multiple testing procedures can improve power as…

Methodology · Statistics 2018-12-04 Wenge Guo , Gavin Lynch , Joseph P. Romano