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Localization microscopy is an imaging technique in which the positions of individual nanoscale point emitters (e.g. fluorescent molecules) are determined at high precision from their images. This is the key ingredient in…
Ultrasound Localization Microscopy (ULM) has proven effective in resolving microvascular structures and local mean velocities at sub-diffraction-limited scales, offering high-resolution imaging capabilities. Dynamic ULM (DULM) enables the…
Row-column arrays have shown to be able to generate 3-D ultrafast ultrasound images with an order of magnitude less independent electronic channels than classic 2D matrix arrays. Unfortunately row-column array images suffer from major…
We proposed a deconvolution optical-resolution photoacoustic microscope for high -resolution imaging of brain. The focal spot of the photoacoustic microscopy is measured to obtain the lateral PSF (point spread function) of the system.…
Atmospheric turbulence characterization is crucial for technologies like free-space optical communications. Existing methods using a spatially-integrated one-dimensional (1D) orbital angular momentum (OAM) spectrum, P(m), obscure the…
Three-dimensional ultrasound enables real-time volumetric visualization of anatomical structures. Unlike traditional 2D ultrasound, 3D imaging reduces reliance on precise probe orientation, potentially making ultrasound more accessible to…
With the advent of microsphere assisted microscopy in 2011, this technique emerged as a simple and easy way to obtain optical super-resolution. Although the possible mechanisms of imaging by microspheres are debated in the literature, most…
Accurate speed-of-sound (SoS) estimation is crucial for ultrasound image formation, yet conventional systems often rely on an assumed value for imaging. We propose to leverage conventional image analysis techniques and metrics as a novel…
Super-resolution optical microscopy is a rapidly evolving scientific field dedicated to imaging sub-wavelength sized objects, leaving its mark in multiple branches of biology and technology. While several super-resolution optical microscopy…
Fast 3D super-resolution imaging is essential for decoding rapidly occurring biological processes. Encoding single molecules to their respective planes enable simultaneous multi-plane super-resolution volume imaging. This saves the…
In ultrasound beamforming, focusing time delays are typically computed with a spatially constant speed-of-sound (SoS) assumption. A mismatch between beamforming and true medium SoS then leads to aberration artifacts. Other imaging…
The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization Microscopy (DULM) has allowed for the quantitative mapping of the…
Acoustic-resolution optoacoustic microscopy (AR-OAM) retrieves anatomical and functional contrast from living tissues at depths not reachable with optical microscopy. The imaging performance of AR-OAM has been advanced with image…
Spherical matrix arrays arguably represent an advantageous tomographic detection geometry for non-invasive deep tissue mapping of vascular networks and oxygenation with volumetric optoacoustic tomography (VOT). Hybridization of VOT with…
We propose a novel OCT-based method for visualizing microvasculature in 3D using reference-free processing of individual complex-valued B-scans with highly overlapped A-scans. In the lateral direction of such a B-scan, the amplitude and…
In multi-photon microscopy (MPM), a recent in-vivo fluorescence microscopy system, the task of image restoration can be decomposed into two interlinked inverse problems: firstly, the characterization of the Point Spread Function (PSF) and…
Transient brain-wide neuroimaging on a microscopic scale is pivotal for brain research, yet current modalities face challenges in meeting such spatiotemporal requirements. Functional ultrasound (fUS) enables transient neurovascular imaging…
Super-resolution microscopy is crucial for imaging sub-wavelength biological structures. However, most techniques rely on nonlinear saturation or stochastic switching of emitters, limiting imaging speed and increasing phototoxicity. Here,…
Scanning electron microscopy (SEM) is indispensable in diverse applications ranging from microelectronics to food processing because it provides large depth-of-field images with a resolution beyond the optical diffraction limit. However,…
The sparsity of millimeter wave (mmWave) channels in the angular and temporal domains is beneficial to channel estimation, while the associated channel parameters can be utilized for localization. However, line-of-sight (LoS) blockage poses…