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In emerging quantum-classical integration applications, the classical time cost-especially from compilation and protocol-level communication often exceeds the execution time of quantum circuits themselves, posing a severe bottleneck to…

Programming Languages · Computer Science 2025-06-16 Tianrui Zou , Yuan Fang , Jing Wang , Menghan Dou , Jun Fu , ZiQiang Zhao , ShuBin Zhao , Lei Yu , Dongyi Zhao , Zhaoyun Chen , Guoping Guo

Variational quantum algorithm (VQA), which is comprised of a classical optimizer and a parameterized quantum circuit, emerges as one of the most promising approaches for harvesting the power of quantum computers in the noisy intermediate…

Quantum Physics · Physics 2021-12-01 Samuel Stein , Yufei Ding , Nathan Wiebe , Bo Peng , Karol Kowalski , Nathan Baker , James Ang , Ang Li

Various physical constraints limit the number of qubits that can be implemented in a single quantum processor, and thus it is necessary to connect multiple quantum processors via quantum interconnects. While several compiler implementations…

Quantum Physics · Physics 2023-02-02 Shin Nishio , Ryo Wakizaka

The rapid advancement of quantum computing has highlighted the need for scalable and efficient software infrastructures to fully exploit its potential. Current quantum processors face significant scalability constraints due to the limited…

The technology of Quantum Computing (QC) is continuously evolving, as researchers explore new technologies and the public gains access to quantum computers with an increasing number of qubits. In addition, the research community and…

This paper presents a comprehensive software stack architecture for integrating quantum computing (QC) capabilities with High-Performance Computing (HPC) environments. While quantum computers show promise as specialized accelerators for…

A system-independent intermediate representation (IR) for pulse-level programming of quantum control systems is required to enable rapid development and reuse of quantum software across diverse platforms. In this work, we demonstrate the…

Quantum Physics · Physics 2025-12-10 Jude Alnas , Aniket S. Dalvi , Kenneth R. Brown

Quantum programming techniques and software have advanced significantly over the past five years, with a majority focusing on high-level language frameworks targeting remote REST library APIs. As quantum computing architectures advance and…

Heterogeneous high-performance computing (HPC) systems offer novel architectures which accelerate specific workloads through judicious use of specialized coprocessors. A promising architectural approach for future scientific computations is…

Quantum computers are the next evolution of computing hardware. Quantum devices are being exposed through the same familiar cloud platforms used for classical computers, and enabling seamless execution of hybrid applications that combine…

Quantum computers have demonstrated utility in simulating quantum systems beyond brute-force classical approaches. As the community builds on these demonstrations to explore using quantum computing for applied research, algorithms and…

Quantum computing holds promise across various fields, particularly with the advent of Noisy Intermediate-Scale Quantum (NISQ) devices, which can outperform classical supercomputers in specific tasks. However, challenges such as noise and…

Quantum computing is advancing rapidly in hardware and algorithms, but broad accessibility demands a comprehensive, efficient, unified software stack. Such a stack must flexibly span diverse hardware and evolving algorithms, expose usable…

Hybrid workflows combining traditional HPC and novel ML methodologies are transforming scientific computing. This paper presents the architecture and implementation of a scalable runtime system that extends RADICAL-Pilot with service-based…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-18 Andre Merzky , Mikhail Titov , Matteo Turilli , Ozgur Kilic , Tianle Wang , Shantenu Jha

Quantum algorithms have been widely studied in the context of combinatorial optimization problems. While this endeavor can often analytically and practically achieve quadratic speedups, theoretical and numeric studies remain limited,…

Quantum Physics · Physics 2023-11-07 Lucas T. Brady , Stuart Hadfield

High-Performance Computing (HPC) systems are the most powerful tools that we currently have to solve complex scientific simulations. Quantum computing (QC) has the potential to enhance HPC systems by accelerating the execution of specific…

Quantum computing (QC) introduces a novel mode of computation with the possibility of greater computational power that remains to be exploited - presenting exciting opportunities for high performance computing (HPC) applications. However,…

We propose an IR for quantum computing that directly exposes quantum and classical data dependencies for the purpose of optimization. The Quantum Intermediate Representation for Optimization (QIRO) consists of two dialects, one input…

Quantum Physics · Physics 2022-04-14 David Ittah , Thomas Häner , Vadym Kliuchnikov , Torsten Hoefler

Hybrid quantum-classical algorithms are central to much of the current research in quantum computing, particularly when considering the noisy intermediate-scale quantum (NISQ) era, with a number of experimental demonstrations having already…

Quantum Physics · Physics 2022-07-15 Adam Callison , Nicholas Chancellor

In the NISQ-era of quantum computing, we should not expect to see quantum devices that provide an exponential improvement in runtime for practical problems, due to the lack of error correction and small number of qubits available.…

Quantum Physics · Physics 2019-07-02 Samuel S. Mendelson , Robert W. Strand , Guy B. Oldaker , Jacob M. Farinholt