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High-performance computing systems are rapidly evolving into heterogeneous platforms that fuse quantum accelerators with traditional classical processing units (CPUs) and graphical processing units (GPUs). This convergence calls for…

Hybrid languages like the quantum intermediate representation (QIR) are essential for programming systems that mix quantum and conventional computing models, while execution of these programs is often deferred to a system-specific…

Intermediate representations (IRs) play a crucial role in the software stack of a quantum computer to facilitate efficient optimizations for executing an application on hardware. One of those IRs is the Quantum Intermediate Representation…

Quantum Physics · Physics 2026-01-15 Yannick Stade , Lukas Burgholzer , Robert Wille

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and verification and validation. Despite considerable progress,…

Quantum Physics · Physics 2018-05-24 Alexander McCaskey , Eugene Dumitrescu , Dmitry Liakh , Travis Humble

Hybrid quantum-high performance computing (Q-HPC) workflows are emerging as a key strategy for running quantum applications at scale in current noisy intermediate-scale quantum (NISQ) devices. These workflows must operate seamlessly across…

The use of mid-circuit measurement and qubit reset within quantum programs has been introduced recently and several applications demonstrated that perform conditional branching based on these measurements. In this work, we go a step further…

Hybrid quantum-classical applications pose significant resource management challenges due to heterogeneity and dynamism in both infrastructure and workloads. Quantum-HPC environments integrate quantum processing units (QPUs) with diverse…

Quantum Physics · Physics 2026-04-07 Pradeep Mantha , Florian J. Kiwit , Nishant Saurabh , Shantenu Jha , Andre Luckow

Classical simulation of quantum computers will continue to play an essential role in the progress of quantum information science, both for numerical studies of quantum algorithms and for modeling noise and errors. Here we introduce the…

Quantum Physics · Physics 2020-06-08 Gian Giacomo Guerreschi , Justin Hogaboam , Fabio Baruffa , Nicolas P. D. Sawaya

Robust execution environments are important for addressing key challenges in quantum computing, such as application development, portability, and reproducibility, and help unlock the development of modular quantum programs, driving forward…

Quantum Physics · Physics 2025-09-26 Aleksander Wennersteen , Matthieu Moreau , Aurelien Nober , Mourad Beji

Emerging quantum applications such as error mitigation, system characterization, and hybrid protocols often require running large families of related quantum circuits. Existing intermediate representations (IRs) and frameworks such as…

Quantum Physics · Physics 2025-07-15 Sourish Wawdhane , Sashwat Anagolum , Poulami Das , Yunong Shi

Quantum circuit execution is the central task in quantum computation. Due to inherent quantum-mechanical constraints, quantum computing workflows often involve a considerable number of independent measurements over a large set of slightly…

Quantum Physics · Physics 2024-06-06 Daniel Claudino , Dmitry I. Lyakh , Alexander J. McCaskey

Hybrid quantum-classical workflows combine quantum processing units (QPUs) with classical hardware to address computational tasks that are challenging or infeasible for conventional systems alone. Coordinating these heterogeneous resources…

Quantum Physics · Physics 2026-03-26 Mar Tejedor , Michele Grossi , Cenk Tüysüz , Ricardo Rocha , Sofia Vallecorsa

Achieving high-performance computation on quantum systems presents a formidable challenge that necessitates bridging the capabilities between quantum hardware and classical computing resources. This study introduces an innovative…

Quantum Physics · Physics 2024-03-19 Kuan-Cheng Chen , Xiaoren Li , Xiaotian Xu , Yun-Yuan Wang , Chen-Yu Liu

A strategy for the orchestration of hybrid classical-quantum workloads on supercomputers featuring quantum devices is proposed. The method makes use of heterogeneous job launches with Slurm to interleave classical and quantum computation,…

Quantum Physics · Physics 2023-12-11 Aniello Esposito , Sebastien Cabaniols , Jessica R. Jones , David Brayford

Task scheduling with constrained time intervals and limited resources remains a fundamental challenge across domains such as manufacturing, logistics, cloud computing, and healthcare. This study presents a novel variant of the Quantum…

Quantum Physics · Physics 2026-05-26 José A. Tirado-Domínguez , Eladio Gutiérrez , Oscar Plata

This paper introduces a vision for Quantum Software Development lifecycle, proposing a hybrid full-stack iterative model that integrates quantum and classical computing. Addressing the current challenges in Quantum Computing (QC) such as…

Software Engineering · Computer Science 2025-04-09 Arif Ali Khan , Davide Taibi , Muhammad Azeem Akbar

Quantum computing (QC) is a new paradigm offering the potential of exponential speedups over classical computing for certain computational problems. Each additional qubit doubles the size of the computational state space available to a QC…

Quantum Physics · Physics 2021-03-22 Wei Tang , Teague Tomesh , Martin Suchara , Jeffrey Larson , Margaret Martonosi

Quantum computing (QC) offers a new computing paradigm that has the potential to provide significant speedups over classical computing. Each additional qubit doubles the size of the computational state space available to a quantum…

Quantum Physics · Physics 2022-05-13 Wei Tang , Margaret Martonosi

Digital quantum computers promise exponential speedups in performing quantum time-evolution, providing an opportunity to simulate quantum dynamics of complex systems in physics and chemistry. However, the task of extracting desired quantum…

Quantum Physics · Physics 2025-03-10 Chong Hian Chee , Daniel Leykam , Adrian M. Mak , Kishor Bharti , Dimitris G. Angelakis

High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of…

Quantum Physics · Physics 2026-04-23 Suman Raj , Siva Sai , Yogesh Simmhan , Kyle Chard , Rajkumar Buyya
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