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Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…

Computation and Language · Computer Science 2025-09-08 Maya Kruse , Shiyue Hu , Nicholas Derby , Yifu Wu , Samantha Stonbraker , Bingsheng Yao , Dakuo Wang , Elizabeth Goldberg , Yanjun Gao

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Long text classification is challenging for Large Language Models (LLMs) due to token limits and high computational costs. This study explores whether a Retrieval Augmented Generation (RAG) approach using only the most relevant text…

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

With generative artificial intelligence (AI), particularly large language models (LLMs), continuing to make inroads in healthcare, it is critical to supplement traditional automated evaluations with human evaluations. Understanding and…

Converting free-text cardiac magnetic resonance (CMR) reports into auditable structured data remains a bottleneck for cohort assembly, longitudinal curation, and clinical decision support. We present CMR-EXTR, a lightweight framework that…

Computation and Language · Computer Science 2026-05-11 Yi Yu , Parker Martin , Zhenyu Bu , Yixuan Liu , Yi-Yu Zheng , Orlando Simonetti , Yuchi Han , Yuan Xue

The advent of Large Language Models has revolutionized tasks across domains, including the automation of legal document analysis, a critical component of modern contract management systems. This paper presents a comprehensive implementation…

Machine Learning · Statistics 2025-10-23 Cuize Han , Sesh Jalagam

Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

A significant amount of data held in Oncology Electronic Medical Records (EMRs) is contained in unstructured provider notes -- including but not limited to the chemotherapy (or cancer treatment) outcome, different biomarkers, the tumor's…

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

Electronic health records (EHRs) contain a vast amount of high-dimensional multi-modal data that can accurately represent a patient's medical history. Unfortunately, most of this data is either unstructured or semi-structured, rendering it…

Computation and Language · Computer Science 2023-12-06 Ashwyn Sharma , David I. Feldman , Aneesh Jain

Electronic Health Records (EHRs) play an important role in the healthcare system. However, their complexity and vast volume pose significant challenges to data interpretation and analysis. Recent advancements in Artificial Intelligence…

Identifying patient cohorts is fundamental to numerous healthcare tasks, including clinical trial recruitment and retrospective studies. Current cohort retrieval methods in healthcare organizations rely on automated queries of structured…

Automated testing plays a crucial role in ensuring software security. It heavily relies on formal specifications to validate the correctness of the system behavior. However, the main approach to defining these formal specifications is…

Software Engineering · Computer Science 2025-04-03 Hui Li , Zhen Dong , Siao Wang , Hui Zhang , Liwei Shen , Xin Peng , Dongdong She

Results from Randomized Controlled Trials (RCTs) establish the comparative effectiveness of interventions, and are in turn critical inputs for evidence-based care. However, results from RCTs are presented in (often unstructured) natural…

Computation and Language · Computer Science 2023-07-19 Somin Wadhwa , Jay DeYoung , Benjamin Nye , Silvio Amir , Byron C. Wallace

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan

The performance of machine learning models on tabular data is critically dependent on high-quality feature engineering. While Large Language Models (LLMs) have shown promise in automating feature extraction (AutoFE), existing methods are…

Artificial Intelligence · Computer Science 2025-11-20 Henrik Bradland , Morten Goodwin , Vladimir I. Zadorozhny , Per-Arne Andersen

A crucial step in cohort studies is to extract the required cohort from one or more study datasets. This step is time-consuming, especially when a researcher is presented with a dataset that they have not previously worked with. When the…

Machine Learning · Computer Science 2024-12-17 Purity Mugambi , Alexandra Meliou , Madalina Fiterau

Large language models (LLMs) are increasingly used to generate summaries from clinical notes. However, their ability to preserve essential diagnostic information remains underexplored, which could lead to serious risks for patient care.…

Computation and Language · Computer Science 2026-02-20 Heloisa Oss Boll , Antonio Oss Boll , Leticia Puttlitz Boll , Ameen Abu Hanna , Iacer Calixto

Meta-analyses statistically aggregate the findings of different randomized controlled trials (RCTs) to assess treatment effectiveness. Because this yields robust estimates of treatment effectiveness, results from meta-analyses are…

Computation and Language · Computer Science 2024-07-26 Hye Sun Yun , David Pogrebitskiy , Iain J. Marshall , Byron C. Wallace
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