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Task-specific deep learning models in histopathology offer promising opportunities for improving diagnosis, clinical research, and precision medicine. However, development of such models is often limited by availability of high-quality…

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Visual domain adaptation (DA) seeks to transfer trained models to unseen, unlabeled domains across distribution shift, but approaches typically focus on adapting convolutional neural network architectures initialized with supervised…

Computer Vision and Pattern Recognition · Computer Science 2022-06-17 Viraj Prabhu , Sriram Yenamandra , Aaditya Singh , Judy Hoffman

Quantitative computed tomography (QCT) plays a crucial role in assessing bone strength and fracture risk by enabling volumetric analysis of bone density distribution in the proximal femur. However, deploying automated segmentation models in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Rochak Dhakal , Chen Zhao , Zixin Shi , Joyce H. Keyak , Tadashi S. Kaneko , Kuan-Jui Su , Hui Shen , Hong-Wen Deng , Weihua Zhou

Self-supervised learning (SSL) is a technique for learning useful representations from unlabeled data. It has been applied effectively to domain adaptation (DA) on images and videos. It is still unknown if and how it can be leveraged for…

Computer Vision and Pattern Recognition · Computer Science 2022-05-16 Idan Achituve , Haggai Maron , Gal Chechik

It is commonly recognized that color variations caused by differences in stains is a critical issue for histopathology image analysis. Existing methods adopt color matching, stain separation, stain transfer or the combination of them to…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Hai-Li Ye , Da-Han Wang

Prognostics and Health Management (PHM) is an emerging field which has received much attention from the manufacturing industry because of the benefits and efficiencies it brings to the table. And Remaining Useful Life (RUL) prediction is at…

Machine Learning · Computer Science 2022-08-18 Manu Joseph , Varchita Lalwani

Domain adaptation (DA) is a quickly expanding area in machine learning that involves adjusting a model trained in one domain to perform well in another domain. While there have been notable progressions, the fundamental concept of numerous…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Yihang Wu , Ahmad Chaddad

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Deep learning has revolutionized the early detection of breast cancer, resulting in a significant decrease in mortality rates. However, difficulties in obtaining annotations and huge variations in distribution between training sets and real…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Yuxiang Yang , Xinyi Zeng , Pinxian Zeng , Binyu Yan , Xi Wu , Jiliu Zhou , Yan Wang

Large-scale volumetric medical images with annotation are rare, costly, and time prohibitive to acquire. Self-supervised learning (SSL) offers a promising pre-training and feature extraction solution for many downstream tasks, as it only…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Ke Yu , Li Sun , Junxiang Chen , Max Reynolds , Tigmanshu Chaudhary , Kayhan Batmanghelich

Breast-Conserving Surgery (BCS) requires precise intraoperative margin assessment to preserve healthy tissue. Deep Ultraviolet Fluorescence Scanning Microscopy (DUV-FSM) offers rapid, high-resolution surface imaging for this purpose;…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Pouya Afshin , David Helminiak , Tianling Niu , Julie M. Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Ultrasound computed tomography (UCT) via full waveform inversion (FWI) enables high-resolution quantitative imaging for tissue characterization and disease diagnosis. However, UCT suffers from large computational burden and severe…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Tianyu Liu , Heyu Ma , Aiduo Wang , Peiwen Li , Boyi Li , Ying Li , Dan Li , Chengcheng Liu , Dean Ta

Deep Learning models have been successfully utilized to extract clinically actionable insights from routinely available histology data. Generally, these models require annotations performed by clinicians, which are scarce and costly to…

Machine Learning · Computer Science 2024-03-13 Tim Lenz , Omar S. M. El Nahhas , Marta Ligero , Jakob Nikolas Kather

Supervised learning is constrained by the availability of labeled data, which are especially expensive to acquire in the field of digital pathology. Making use of open-source data for pre-training or using domain adaptation can be a way to…

Computer Vision and Pattern Recognition · Computer Science 2022-01-20 Christian Abbet , Linda Studer , Andreas Fischer , Heather Dawson , Inti Zlobec , Behzad Bozorgtabar , Jean-Philippe Thiran

A major limitation in applying deep learning to artificial intelligence (AI) systems is the scarcity of high-quality curated datasets. We investigate strong augmentation based self-supervised learning (SSL) techniques to address this…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 John D. Miller , Vignesh A. Arasu , Albert X. Pu , Laurie R. Margolies , Weiva Sieh , Li Shen

Tubular structure segmentation (TSS) is important for various applications, such as hemodynamic analysis and route navigation. Despite significant progress in TSS, domain shifts remain a major challenge, leading to performance degradation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Jiale Zhou , Wenhan Wang , Shikun Li , Xiaolei Qu , Xin Guo , Yizhong Liu , Wenzhong Tang , Xun Lin , Yefeng Zheng

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

Domain shift is a critical problem for pathology AI as pathology data is heavily influenced by center-specific conditions. Current pathology domain adaptation methods focus on image patches rather than WSI, thus failing to capture global…

Artificial Intelligence · Computer Science 2025-08-11 Jingsong Liu , Han Li , Chen Yang , Michael Deutges , Ario Sadafi , Xin You , Katharina Breininger , Nassir Navab , Peter J. Schüffler
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