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In scientific applications, multivariate observations often come in tandem with temporal or spatial covariates, with which the underlying signals vary smoothly. The standard approaches such as principal component analysis and factor…

Statistics Theory · Mathematics 2019-10-15 Mark Koudstaal , Dengdeng Yu , Dehan Kong , Fang Yao

Cosmological fine-tuning has traditionally been associated with the narrowness of the intervals in which the parameters of the physical models must be located to make life possible. A more thorough approach focuses on the probability of the…

History and Philosophy of Physics · Physics 2022-04-26 Daniel Andrés Díaz-Pachón , Ola Hössjer , Robert J. Marks

In this paper, nonstandard multistep methods are considered. It is shown that under some (sufficient and necessary) conditions, these methods attain the same order as their standard counterparts - to prove this statement, a nonstandard…

Numerical Analysis · Mathematics 2026-01-19 Bálint Takács

Nonlinear dynamic models are widely used for characterizing functional forms of processes that govern complex biological pathway systems. Over the past decade, validation and further development of these models became possible due to data…

Methodology · Statistics 2019-08-13 Itai Dattner , Shota Gugushvili , Harold Ship , Eberhard O. Voit

The problem of decomposing non-manifold object has already been studied in solid modeling. However, the few proposed solutions are limited to the problem of decomposing solids described through their boundaries. In this thesis we study the…

Graphics · Computer Science 2019-04-03 Franco Morando

Here, I present a novel method for normalizing a finite set of numbers, which is studied by the domain of biological vision. Normalizing in this context means searching the maximum and minimum number in a set and then rescaling all numbers…

Adaptation and Self-Organizing Systems · Physics 2007-09-19 Matthias S. Keil

Multidimensional scaling (MDS) is a widely used approach to representing high-dimensional, dependent data. MDS works by assigning each observation a location on a low-dimensional geometric manifold, with distance on the manifold…

Methodology · Statistics 2023-08-16 Bolun Liu , Shane Lubold , Adrian E. Raftery , Tyler H. McCormick

Methodologies for reducing the design-space dimensionality in shape optimization have been recently developed based on unsupervised machine learning methods. These methods provide reduced dimensionality representations of the design space,…

Optimization and Control · Mathematics 2022-12-21 Andrea Serani , Matteo Diez

Computer simulation models are widely used to study complex physical systems. A related fundamental topic is the inverse problem, also called calibration, which aims at learning about the values of parameters in the model based on…

Methodology · Statistics 2024-01-03 Yang Li , Shifeng Xiong

Many statistical methodologies for high-dimensional data assume the population is normal. Although a few multivariate normality tests have been proposed, to the best of our knowledge, none of them can properly control the type I error when…

Methodology · Statistics 2021-05-04 Hao Chen , Yin Xia

When addressing spatial biological questions using mathematical models, symmetries within the system are often exploited to simplify the problem by reducing its physical dimension. In a reduced-dimension model molecular movement is…

Quantitative Methods · Quantitative Biology 2025-02-17 Natasha S. Savage

A nonlinear elasticity model for comparing images is formulated and analyzed, in which optimal transformations between images are sought as minimizers of an integral functional. The existence of minimizers in a suitable class of…

Analysis of PDEs · Mathematics 2023-03-21 John M. Ball , Christopher L. Horner

The dynamics of many-body systems can often be captured in terms of only a few relevant variables. Mathematical and numerical approaches exist to identify these variables by exploiting a separation of time scales between slow relevant and…

Nonlinear dimensionality reduction methods provide a valuable means to visualize and interpret high-dimensional data. However, many popular methods can fail dramatically, even on simple two-dimensional manifolds, due to problems such as…

Machine Learning · Statistics 2020-07-08 Daniel Ting , Michael I. Jordan

Carleman linearization is a mathematical technique that transforms nonlinear dynamical systems into infinite-dimensional linear systems, enabling simplified analysis. Initially developed for ordinary differential equations (ODEs) and later…

Optimization and Control · Mathematics 2025-09-03 Marcos A. Hernandez-Ortega , C. M. Rergis , A. Roman-Messina , Erlan R. Murillo-Aguirre

Topology optimization (TO) can be viewed as seeking an optimal solution in the design space of a given TO problem. For weakly non-linear TO problems, e.g., compliance minimization, sensitivity-based methods typically converge well, whereas…

Optimization and Control · Mathematics 2026-03-25 Ziliang Wang , Jiahua Wu , Jun Yang , Shintaro Yamasaki

Nonparametric regression models have recently surged in their power and popularity, accompanying the trend of increasing dataset size and complexity. While these models have proven their predictive ability in empirical settings, they are…

Methodology · Statistics 2020-07-23 Spencer Woody , Carlos M. Carvalho , Jared S. Murray

This article introduces a functional method for lower-dimensional smooth representations in terms of time-varying dissimilarities. The method incorporates dissimilarity representation in multidimensional scaling and smoothness approach of…

Methodology · Statistics 2025-05-02 Liting Li

In modelling of chemical, physical or biological systems it may occur that the coefficients, multiplying various terms in the equation of interest, differ greatly in magnitude, if a particular system of units is used. Such is, for instance,…

Computational Engineering, Finance, and Science · Computer Science 2020-05-26 Simone Rusconi , Denys Dutykh , Arghir Zarnescu , Dmitri Sokolovski , Elena Akhmatskaya

Ordinary Differential Equations are widespread tools to model chemical, physical, biological process but they usually rely on parameters which are of critical importance in terms of dynamic and need to be estimated directly from the data.…

Methodology · Statistics 2014-10-29 Nicolas Brunel , Quentin Clairon