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Access to the proper infrastructure is critical when performing medical image segmentation with Deep Learning. This requirement makes it difficult to run state-of-the-art segmentation models in resource-constrained scenarios like primary…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 John Kalkhof , Camila González , Anirban Mukhopadhyay

Neural cellular automata (NCA) provide a lightweight alternative to encoder-decoder segmentation networks. However, it can be difficult to decide when a prediction should be trusted. Here, we study uncertainty estimation for NCA-based…

Image and Video Processing · Electrical Eng. & Systems 2026-05-27 Ario Sadafi , Michael Deutges , Nassir Navab , Carsten Marr

Medical image segmentation relies heavily on large-scale deep learning models, such as UNet-based architectures. However, the real-world utility of such models is limited by their high computational requirements, which makes them…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 John Kalkhof , Anirban Mukhopadhyay

Cellular automata and their differentiable counterparts, Neural Cellular Automata (NCA), are highly expressive and capable of surprisingly complex behaviors. This paper explores how NCAs perform when applied to tasks requiring precise…

Neural and Evolutionary Computing · Computer Science 2025-12-03 Kevin Xu , Risto Miikkulainen

Neural Cellular Automata (NCAs) are bio-inspired dynamical systems in which identical cells iteratively apply a learned local update rule to self-organize into complex patterns, exhibiting regeneration, robustness, and spontaneous dynamics.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ehsan Pajouheshgar , Yitao Xu , Ali Abbasi , Alexander Mordvintsev , Wenzel Jakob , Sabine Süsstrunk

The detection and segmentation of white blood cells in blood smear images is a key step in medical diagnostics, supporting various downstream tasks such as automated blood cell counting, morphological analysis, cell classification, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Michael Deutges , Chen Yang , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

In the field of medical imaging, the U-Net architecture, along with its variants, has established itself as a cornerstone for image segmentation tasks, particularly due to its strong performance when trained on limited datasets. Despite its…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Steven Korevaar , Ruwan Tennakoon , Alireza Bab-Hadiashar

Neural Cellular Automata (NCA) represent a powerful framework for modeling biological self-organization, extending classical rule-based systems with trainable, differentiable (or evolvable) update rules that capture the adaptive…

Artificial Intelligence · Computer Science 2025-09-16 Benedikt Hartl , Michael Levin , Léo Pio-Lopez

In this work we present a method of automatic segmentation of defective skulls for custom cranial implant design and 3D printing purposes. Since such tissue models are usually required in patient cases with complex anatomical defects and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Oldřich Kodym , Michal Španěl , Adam Herout

This study significantly advances multi-texture synthesis using Neural Cellular Automata (NCAs) by introducing a novel training methodology that enables robust self-regeneration of textures in damaged regions. This inherent healing…

Neural and Evolutionary Computing · Computer Science 2026-05-14 Mirela-Magdalena Catrina , Ioana Cristina Plajer , Alexandra Băicoianu

Neural cellular automata represent an evolution of the traditional cellular automata model, enhanced by the integration of a deep learning-based transition function. This shift from a manual to a data-driven approach significantly increases…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Andrea Menta , Alberto Archetti , Matteo Matteucci

Neural Cellular Automata (NCAs) are a promising new approach to model self-organizing processes, with potential applications in life science. However, their deterministic nature limits their ability to capture the stochasticity of…

Artificial Intelligence · Computer Science 2025-06-26 Salvatore Milite , Giulio Caravagna , Andrea Sottoriva

We propose Neural Cellular Automata (NCA) to simulate the microstructure development during the solidification process in metals. Based on convolutional neural networks, NCA can learn essential solidification features, such as preferred…

Materials Science · Physics 2023-09-08 Jian Tang , Siddhant Kumar , Laura De Lorenzis , Ehsan Hosseini

Skin lesion segmentation is an important step for automatic melanoma diagnosis. Due to the non-negligible diversity of lesions from different patients, extracting powerful context for fine-grained semantic segmentation is still challenging…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Ruxin Wang , Shuyuan Chen , Chaojie Ji , Ye Li

Denoising Diffusion Models (DDMs) are widely used for high-quality image generation and medical image segmentation but often rely on Unet-based architectures, leading to high computational overhead, especially with high-resolution images.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Avni Mittal , John Kalkhof , Anirban Mukhopadhyay , Arnav Bhavsar

Cellular Automata (CA) have long been foundational in simulating dynamical systems computationally. With recent innovations, this model class has been brought into the realm of deep learning by parameterizing the CA's update rule using an…

Neural and Evolutionary Computing · Computer Science 2023-11-29 Magnus Petersen

Neural Cellular Automata (NCA) are a powerful combination of machine learning and mechanistic modelling. We train NCA to learn complex dynamics from time series of images and PDE trajectories. Our method is designed to identify underlying…

Pattern Formation and Solitons · Physics 2024-04-23 Alex D. Richardson , Tibor Antal , Richard A. Blythe , Linus J. Schumacher

In this paper, we propose a new approach for building cellular automata to solve real-world segmentation problems. We design and train a cellular automaton that can successfully segment high-resolution images. We consider a colony that…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Mark Sandler , Andrey Zhmoginov , Liangcheng Luo , Alexander Mordvintsev , Ettore Randazzo , Blaise Agúera y Arcas

While nowadays deep neural networks achieve impressive performances on semantic segmentation tasks, they are usually trained by optimizing pixel-wise losses such as cross-entropy. As a result, the predictions outputted by such networks…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Yifu Chen , Arnaud Dapogny , Matthieu Cord

The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Jun Wang , Yang Zhao , Linglong Qian , Xiaohan Yu , Yongsheng Gao
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