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Retrieval augmented generation (RAG) exhibits outstanding performance in promoting the knowledge capabilities of large language models (LLMs) with retrieved documents related to user queries. However, RAG only focuses on improving the…

Information Retrieval · Computer Science 2024-06-25 Dongyang Li , Junbing Yan , Taolin Zhang , Chengyu Wang , Xiaofeng He , Longtao Huang , Hui Xue , Jun Huang

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

Retrieval-augmented generation (RAG) systems combine large language models (LLMs) with external knowledge retrieval, making them highly effective for knowledge-intensive tasks. A crucial but often under-explored component of these systems…

Computation and Language · Computer Science 2025-05-19 Jiashuo Sun , Xianrui Zhong , Sizhe Zhou , Jiawei Han

Although the Retrieval-Augmented Generation (RAG) paradigms can use external knowledge to enhance and ground the outputs of Large Language Models (LLMs) to mitigate generative hallucinations and static knowledge base problems, they still…

Computation and Language · Computer Science 2024-05-24 Diji Yang , Jinmeng Rao , Kezhen Chen , Xiaoyuan Guo , Yawen Zhang , Jie Yang , Yi Zhang

Incremental learning targets at achieving good performance on new categories without forgetting old ones. Knowledge distillation has been shown critical in preserving the performance on old classes. Conventional methods, however,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-08 Peng Zhou , Long Mai , Jianming Zhang , Ning Xu , Zuxuan Wu , Larry S. Davis

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Retrieval Augmented Generation (RAG) frameworks have shown significant promise in leveraging external knowledge to enhance the performance of large language models (LLMs). However, conventional RAG methods often retrieve documents based…

Computation and Language · Computer Science 2025-04-02 Pouya Pezeshkpour , Estevam Hruschka

Fine-tuning is an immensely resource-intensive process when retraining Large Language Models (LLMs) to incorporate a larger body of knowledge. Although many fine-tuning techniques have been developed to reduce the time and computational…

Computation and Language · Computer Science 2025-08-01 Hruday Markondapatnaikuni , Basem Suleiman , Abdelkarim Erradi , Shijing Chen

In this paper, we introduce Modality-Inconsistent Continual Learning (MICL), a new continual learning scenario for Multimodal Large Language Models (MLLMs) that involves tasks with inconsistent modalities (image, audio, or video) and…

Machine Learning · Computer Science 2026-05-13 Weiguo Pian , Shijian Deng , Shentong Mo , Mingrui Liu , Yunhui Guo , Yapeng Tian

Continual learning and machine unlearning are crucial challenges in machine learning, typically addressed separately. Continual learning focuses on adapting to new knowledge while preserving past information, whereas unlearning involves…

Machine Learning · Computer Science 2024-12-30 Romit Chatterjee , Vikram Chundawat , Ayush Tarun , Ankur Mali , Murari Mandal

Despite the critical importance of the medical domain in Deep Learning, most of the research in this area solely focuses on training models in static environments. It is only in recent years that research has begun to address dynamic…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Marina Ceccon , Davide Dalle Pezze , Alessandro Fabris , Gian Antonio Susto

Retrieval-Augmented Generation (RAG) has been shown to enhance the factual accuracy of Large Language Models (LLMs), but existing methods often suffer from limited reasoning capabilities in effectively using the retrieved evidence,…

Computation and Language · Computer Science 2024-10-03 Shayekh Bin Islam , Md Asib Rahman , K S M Tozammel Hossain , Enamul Hoque , Shafiq Joty , Md Rizwan Parvez

In-context learning (ICL) allows large models to adapt to tasks using a few examples, yet its extension to vision-language models (VLMs) remains fragile. Our analysis reveals that the fundamental limitation lies in an inductive gap, models…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Haoyu Wang , Haonan Wang , Yuyan Chen , Jun Chen , Gang Liu , Qian Wang , Jiahong Yan , Yanghua Xiao

Multimodal Retrieval Augmented Generation (mRAG) plays an important role in mitigating the "hallucination" issue inherent in multimodal large language models (MLLMs). Although promising, existing heuristic mRAGs typically predefined fixed…

Computation and Language · Computer Science 2025-05-27 Yangning Li , Yinghui Li , Xinyu Wang , Yong Jiang , Zhen Zhang , Xinran Zheng , Hui Wang , Hai-Tao Zheng , Philip S. Yu , Fei Huang , Jingren Zhou

The question-answering system for Life science research, which is characterized by the rapid pace of discovery, evolving insights, and complex interactions among knowledge entities, presents unique challenges in maintaining a comprehensive…

Computation and Language · Computer Science 2024-08-15 Chengrui Wang , Qingqing Long , Meng Xiao , Xunxin Cai , Chengjun Wu , Zhen Meng , Xuezhi Wang , Yuanchun Zhou

Processing long contexts presents a significant challenge for large language models (LLMs). While recent advancements allow LLMs to handle much longer contexts than before (e.g., 32K or 128K tokens), it is computationally expensive and can…

Computation and Language · Computer Science 2025-04-10 Hongjin Qian , Zheng Liu , Peitian Zhang , Kelong Mao , Defu Lian , Zhicheng Dou , Tiejun Huang

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Multimodal deep learning has shown promise in depression detection by integrating text, audio, and video signals. Recent work leverages sentiment analysis to enhance emotional understanding, yet suffers from high computational cost, domain…

Machine Learning · Computer Science 2025-11-05 Ruibo Hou , Shiyu Teng , Jiaqing Liu , Shurong Chai , Yinhao Li , Lanfen Lin , Yen-Wei Chen

Large Language Models (LLMs) have shown remarkable reasoning capabilities, while their practical applications are limited by severe factual hallucinations due to limitations in the timeliness, accuracy, and comprehensiveness of their…

Artificial Intelligence · Computer Science 2025-06-10 Xinyan Guan , Jiali Zeng , Fandong Meng , Chunlei Xin , Yaojie Lu , Hongyu Lin , Xianpei Han , Le Sun , Jie Zhou

Retrieval-Augmented Generation systems are essential for providing fact-based guidance from Malaysian Clinical Practice Guidelines. However, their effectiveness with image-based queries is limited, as general Vision-Language Model captions…

Computation and Language · Computer Science 2025-11-10 Lee Qi Zun , Mohamad Zulhilmi Bin Abdul Halim , Goh Man Fye