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Large language models (LLMs) often exhibit limited performance on domain-specific tasks due to the natural disproportionate representation of specialized information in their training data and the static nature of these datasets. Knowledge…

Computation and Language · Computer Science 2025-09-30 Chaojun Nie , Jun Zhou , Guanxiang Wang , Shisong Wu , Zichen Wang

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

In medical healthcare, obtaining detailed annotations is challenging, highlighting the need for robust Vision-Language Models (VLMs). Pretrained VLMs enable fine-tuning on small datasets or zero-shot inference, achieving performance…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Phuc Pham , Nhu Pham , Ngoc Quoc Ly

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Vision-language retrieval-augmented generation (RAG) has become an effective approach for tackling Knowledge-Based Visual Question Answering (KB-VQA), which requires external knowledge beyond the visual content presented in images. The…

Information Retrieval · Computer Science 2025-09-15 Wei Yang , Jingjing Fu , Rui Wang , Jinyu Wang , Lei Song , Jiang Bian

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

Continual learning in computer vision faces the critical challenge of catastrophic forgetting, where models struggle to retain prior knowledge while adapting to new tasks. Although recent studies have attempted to leverage the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Xusheng Cao , Haori Lu , Linlan Huang , Fei Yang , Xialei Liu , Ming-Ming Cheng

Retrieval-Augmented Generation (RAG) is an effective method to enhance the capabilities of large language models (LLMs). Existing methods typically optimize the retriever or the generator in a RAG system by directly using the top-k…

Computation and Language · Computer Science 2025-10-07 Shaohan Wang , Licheng Zhang , Zheren Fu , Zhendong Mao , Yongdong Zhang

Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities in processing and generating content across multiple data modalities. However, a significant drawback of MLLMs is their reliance on static training data,…

Artificial Intelligence · Computer Science 2024-09-26 Zhanpeng Chen , Chengjin Xu , Yiyan Qi , Jian Guo

Continual Learning (CL) aims to enable Deep Neural Networks (DNNs) to learn new data without forgetting previously learned knowledge. The key to achieving this goal is to avoid confusion at the feature level, i.e., avoiding confusion within…

Machine Learning · Computer Science 2024-08-07 Shaoxu Cheng , Kanglei Geng , Chiyuan He , Zihuan Qiu , Linfeng Xu , Heqian Qiu , Lanxiao Wang , Qingbo Wu , Fanman Meng , Hongliang Li

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Retrieval-augmented generation combined with reinforcement learning has shown promise for grounding large language models in trustworthy medical evidence. However, existing methods rely on exact-match binary rewards, which in clinical…

Artificial Intelligence · Computer Science 2026-05-28 Yuwei Miao , Gen Li , Yunsheng Zeng , Xiandong Li , Yujin Wang , Siyu Chen , Luning Wang , Yunhao Qiao , Junfeng Wang , Jianwei Lv , Bo Yuan

This paper focuses on the dynamic optimization of the Retrieval-Augmented Generation (RAG) architecture. It proposes a state-aware dynamic knowledge retrieval mechanism to enhance semantic understanding and knowledge scheduling efficiency…

Computation and Language · Computer Science 2025-04-29 Jacky He , Guiran Liu , Binrong Zhu , Hanlu Zhang , Hongye Zheng , Xiaokai Wang

Current general-purpose large language models (LLMs) commonly exhibit knowledge hallucination and insufficient domain-specific adaptability in domain-specific tasks, limiting their effectiveness in specialized question answering scenarios.…

Information Retrieval · Computer Science 2025-09-16 Mengzheng Yang , Yanfei Ren , David Osei Opoku , Ruochang Li , Peng Ren , Chunxiao Xing

Textual descriptions for multimodal inputs entail recurrent refinement of queries to produce relevant output images. Despite efforts to address challenges such as scaling model size and data volume, the cost associated with pre-training and…

Machine Learning · Computer Science 2025-08-14 Amit Kumar Jaiswal , Haiming Liu , Ingo Frommholz

Dynamically integrating new or rapidly evolving information after (Large) Language Model pre-training remains challenging, particularly in low-data scenarios or when dealing with private and specialized documents. In-context learning and…

Machine Learning · Computer Science 2025-08-11 Lucas Caccia , Alan Ansell , Edoardo Ponti , Ivan Vulić , Alessandro Sordoni

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

Retrieval-Augmented Generation (RAG) systems rely heavily on the retrieval stage, particularly the coarse-ranking process. Existing coarse-ranking optimization approaches often struggle to balance domain-specific knowledge learning with…

Computation and Language · Computer Science 2025-09-09 Hao Lin , Peitong Xie , Jingxue Chen , Jie Lin , Qingkun Tang , Qianchun Lu

In medical image segmentation across multiple modalities (e.g., MRI, CT, etc.) and heterogeneous data sources (e.g., different hospitals and devices), Domain Generalization (DG) remains a critical challenge in AI-driven healthcare. This…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yucheng Song , Chenxi Li , Haokang Ding , Zhining Liao , Zhifang Liao

Retrieval-augmented generation (RAG) enables large language models (LLMs) to dynamically access external information, which is powerful for answering questions over previously unseen documents. Nonetheless, they struggle with high-level…

Artificial Intelligence · Computer Science 2026-04-21 Chi-Hsiang Hsiao , Yi-Cheng Wang , Tzung-Sheng Lin , Yi-Ren Yeh , Chu-Song Chen