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Existing volumetric medical image segmentation models are typically task-specific, excelling at specific target but struggling to generalize across anatomical structures or modalities. This limitation restricts their broader clinical use.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Haoyu Wang , Sizheng Guo , Jin Ye , Zhongying Deng , Junlong Cheng , Tianbin Li , Jianpin Chen , Yanzhou Su , Ziyan Huang , Yiqing Shen , Bin Fu , Shaoting Zhang , Junjun He , Yu Qiao

We present ENSAM (Equivariant, Normalized, Segment Anything Model), a lightweight and promptable model for universal 3D medical image segmentation. ENSAM combines a SegResNet-based encoder with a prompt encoder and mask decoder in a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Elias Stenhede , Agnar Martin Bjørnstad , Arian Ranjbar

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

Reconstructing 3D representations from 2D inputs is a fundamental task in computer vision and graphics, serving as a cornerstone for understanding and interacting with the physical world. While traditional methods achieve high fidelity,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Weijie Wang , Qihang Cao , Sensen Gao , Donny Y. Chen , Haofei Xu , Wenjing Bian , Songyou Peng , Tat-Jen Cham , Chuanxia Zheng , Andreas Geiger , Jianfei Cai , Jia-Wang Bian , Bohan Zhuang

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have shown strong performance in various vision tasks, particularly image segmentation, due to their impressive zero-shot segmentation capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Pengfei Gu , Haoteng Tang , Islam A. Ebeid , Jose A. Nunez , Fabian Vazquez , Diego Adame , Marcus Zhan , Huimin Li , Bin Fu , Danny Z. Chen

Multi-modal images play a crucial role in comprehensive evaluations in medical image analysis providing complementary information for identifying clinically important biomarkers. However, in clinical practice, acquiring multiple modalities…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Hyunjin Park

Foundation models have transformed medical image analysis by providing robust feature representations that reduce the need for large-scale task-specific training. However, current benchmarks in dermatology often reduce the complex…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Furkan Yuceyalcin , Abdurrahim Yilmaz , Burak Temelkuran

Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between…

Computers and Society · Computer Science 2024-04-05 Yuting He , Fuxiang Huang , Xinrui Jiang , Yuxiang Nie , Minghao Wang , Jiguang Wang , Hao Chen

Recent advancements in foundation models have shown significant potential in medical image analysis. However, there is still a gap in models specifically designed for medical image localization. To address this, we introduce MedLAM, a 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Wenhui Lei , Xu Wei , Xiaofan Zhang , Kang Li , Shaoting Zhang

Foundation models such as Segment Anything Model 2 (SAM 2) exhibit strong generalization on natural images and videos but perform poorly on medical data due to differences in appearance statistics, imaging physics, and three-dimensional…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Satrajit Chakrabarty , Sourya Sengupta , Gopal Avinash , Ravi Soni

3D medical image analysis is pivotal in numerous clinical applications. However, the scarcity of labeled data and limited generalization capabilities hinder the advancement of AI-empowered models. Radiology reports are easily accessible and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xuefeng Ni , Linshan Wu , Jiaxin Zhuang , Qiong Wang , Mingxiang Wu , Varut Vardhanabhuti , Lihai Zhang , Hanyu Gao , Hao Chen

Pathology foundation models (PFMs) have emerged as powerful tools for analyzing whole slide images (WSIs). However, adapting these pretrained PFMs for specific clinical tasks presents considerable challenges, primarily due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Neeraj Kumar , Swaraj Nanda , Siddharth Singi , Jamal Benhamida , David Kim , Jie-Fu Chen , Amir Momeni-Boroujeni , Gregory M. Goldgof , Gabriele Campanella , Chad Vanderbilt

Understanding 3D medical image volumes is critical in the medical field, yet existing 3D medical convolution and transformer-based self-supervised learning (SSL) methods often lack deep semantic comprehension. Recent advancements in…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Qiuhui Chen , Xuancheng Yao , Huping Ye , Yi Hong

Understanding 3D medical image volumes is a critical task in the medical domain. However, existing 3D convolution and transformer-based methods have limited semantic understanding of an image volume and also need a large set of volumes for…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Qiuhui Chen , Huping Ye , Yi Hong

Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yongrui Yu , Yannian Gu , Shaoting Zhang , Xiaofan Zhang

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni
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