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We study the allocation of deceased-donor lungs to patients in need of a transplant. Patients make sequential decisions in an order dictated by a priority policy. Using data from a prominent Organ Procurement Organization in the United…

General Economics · Economics 2024-11-19 Laura Doval , Federico Echenique Wanying Huang , Yi Xin

Kidney transplants are sharply overdemanded in the United States. A recent innovation to address organ shortages is a kidney exchange, in which willing but medically incompatible patient-donor pairs swap donors so that two successful…

Computer Science and Game Theory · Computer Science 2019-12-24 Irena Gao

Cloud computing enables the dynamic provisioning of server resources. To exploit this opportunity, a policy is needed for dynamically allocating (and deallocating) servers in response to the current load conditions. In this paper we…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-24 Niklas Carlsson , Derek Eager

The dynamic portfolio optimization problem in finance frequently requires learning policies that adhere to various constraints, driven by investor preferences and risk. We motivate this problem of finding an allocation policy within a…

Artificial Intelligence · Computer Science 2020-12-23 Nymisha Bandi , Theja Tulabandhula

Given the limited pool of donor organs, accurate predictions of survival on the wait list and post transplantation are crucial for cardiac transplantation decisions and policy. However, current clinical risk scores do not yield accurate…

Applications · Statistics 2017-04-13 J. Yoon , W. R. Zame , A. Banerjee , M. Cadeiras , A. M. Alaa , M. van der Schaar

Allocation of scarce healthcare resources under limited logistic and infrastructural facilities is a major issue in the modern society. We consider the problem of allocation of healthcare resources like vaccines to people or hospital beds…

Multiagent Systems · Computer Science 2023-03-21 Aadityan Ganesh , Prajakta Nimbhorkar , Pratik Ghosal , Vishwa Prakash HV

Scarcity of health care resources could result in the unavoidable consequence of rationing. For example, ventilators are often limited in supply, especially during public health emergencies or in resource-constrained health care settings,…

Machine Learning · Computer Science 2024-08-23 Yikuan Li , Chengsheng Mao , Kaixuan Huang , Hanyin Wang , Zheng Yu , Mengdi Wang , Yuan Luo

In large-scale systems there are fundamental challenges when centralised techniques are used for task allocation. The number of interactions is limited by resource constraints such as on computation, storage, and network communication. We…

Artificial Intelligence · Computer Science 2022-05-12 Niall Creech , Natalia Criado Pacheco , Simon Miles

Organ transplants can improve the life expectancy and quality of life for the recipient but carries the risk of serious post-operative complications, such as septic shock and organ rejection. The probability of a successful transplant…

Machine Learning · Computer Science 2016-11-15 Jinsung Yoon , Ahmed M. Alaa , Martin Cadeiras , Mihaela van der Schaar

Problem Definition: Managing inpatient flow in large hospital systems is challenging due to the complexity of assigning randomly arriving patients -- either waiting for primary units or being overflowed to alternative units. Current…

Optimization and Control · Mathematics 2026-05-08 Jingjing Sun , Jim Dai , Pengyi Shi

Existing statistical methods can estimate a policy, or a mapping from covariates to decisions, which can then instruct decision makers (e.g., whether to administer hypotension treatment based on covariates blood pressure and heart rate).…

Methodology · Statistics 2023-06-26 Samuel J. Weisenthal , Sally W. Thurston , Ashkan Ertefaie

In this paper we employ a lifecycle model that uses utility of consumption and bequest to determine an optimal Deferred Income Annuity (DIA) purchase policy. We lay out a mathematical framework to formalize the optimization process. The…

Portfolio Management · Quantitative Finance 2021-11-03 F. Habib , H. Huang , A. Mauskopf , B. Nikolic , T. S. Salisbury

Human decision making is well known to be imperfect and the ability to analyse such processes individually is crucial when attempting to aid or improve a decision-maker's ability to perform a task, e.g. to alert them to potential biases or…

Machine Learning · Computer Science 2022-10-03 Alex J. Chan , Alicia Curth , Mihaela van der Schaar

A key challenge in multi-robot and multi-agent systems is generating solutions that are robust to other self-interested or even adversarial parties who actively try to prevent the agents from achieving their goals. The practicality of…

Artificial Intelligence · Computer Science 2017-10-19 Trong Nghia Hoang , Yuchen Xiao , Kavinayan Sivakumar , Christopher Amato , Jonathan How

Recent policy optimization approaches (Schulman et al., 2015a; 2017) have achieved substantial empirical successes by constructing new proxy optimization objectives. These proxy objectives allow stable and low variance policy learning, but…

Machine Learning · Computer Science 2020-02-24 Marcin B. Tomczak , Dongho Kim , Peter Vrancx , Kee-Eung Kim

Rising provider turnover results in frequently needing to rematch patients with available providers. However, the rematching process is cumbersome for both patients and health systems, resulting in labor-intensive and ad hoc reassignments.…

Computers and Society · Computer Science 2025-06-13 Naveen Raman , Holly Wiberg

The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

Optimization and Control · Mathematics 2021-09-22 David Rey , Ahmed W Hammad , Meead Saberi

This chapter deals with the design of dynamic allocation functions for systems with saturating actuators. The goal of the allocator consists in redistributing the desired control effort within the multiple actuators by penalizing each…

Optimization and Control · Mathematics 2024-07-12 Thiago Alves Lima , Sophie Tarbouriech

Decision makers often aim to learn a treatment assignment policy under a capacity constraint on the number of agents that they can treat. When agents can respond strategically to such policies, competition arises, complicating estimation of…

Machine Learning · Statistics 2025-03-31 Roshni Sahoo , Stefan Wager

Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be…

Other Quantitative Biology · Quantitative Biology 2023-06-02 Raja Al-Bahou , Julia Bruner , Helen Moore , Ali Zarrinpar