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Optical metasurfaces provide novel solutions to label-free biochemical sensing by localizing light resonantly beyond the diffraction limit, thereby selectively enhancing light-matter interactions for improved analytical performance.…

Fluorescence microscopy is widely employed for the analysis of living biological samples; however, the utility of the resulting recordings is frequently constrained by noise, temporal variability, and inconsistent visualisation of signals…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Hassan Eshkiki , Sarah Costa , Mostafa Mohammadpour , Farinaz Tanhaei , Christopher H. George , Fabio Caraffini

Label-free nonlinear optical microscopy has become a powerful tool for biomedical research. However, the possible photodamage risk hinder further clinical applications. To reduce these adverse effects, we constructed a new platform of…

Optics · Physics 2022-10-26 Geng Wang , Stephen A. Boppart , Haohua Tu

Cross-grating phase microscopy (CGM) is a quantitative phase microscopy technique based on the association of a 2-dimensional diffraction grating (cross-grating) and a regular camera sensor, separated by a millimetric distance. This simple…

Optics · Physics 2024-11-04 Baptiste Marthy , Guillaume Baffou

We analyze a whispering gallery mode biosensor with a metallic nanorod bound to its surface. It is found that a localized surface plasmon resonance in the nanorod can reduce the optical mode volume of the resonator by as much as four orders…

Optics · Physics 2017-02-01 Jon D. Swaim , Joachim Knittel , Warwick P. Bowen

Recent advances in large language models (LLMs) and biomedical foundation models (BioFMs) have achieved strong results in biological text reasoning, molecular modeling, and single-cell analysis, yet they remain siloed in disjoint embedding…

Quantitative Methods · Quantitative Biology 2025-10-03 Ching-Huei Tsou , Michal Ozery-Flato , Ella Barkan , Diwakar Mahajan , Ben Shapira

Image denoising plays a critical role in biomedical and microscopy imaging, especially when acquiring wide-field fluorescence-stained images. This task faces challenges in multiple fronts, including limitations in image acquisition…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Qijun Yang , Yating Huang , Lintao Xiang , Hujun Yin

We demonstrate the capabilities of a novel frequency-domain terahertz spectrometer based on a comb-locked frequency synthesizer, which provides absolute frequency calibration. The inherent stability and repeatability of the scans allow for…

Whispering-gallery mode (WGM) resonators combine small optical mode volumes with narrow resonance linewidths, making them exciting platforms for a variety of applications. Here we report a flying WGM microlaser, realized by optically…

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

In this paper, we propose BeamSense, a completely novel approach to implement standard-compliant Wi-Fi sensing applications. Wi-Fi sensing enables game-changing applications in remote healthcare, home entertainment, and home surveillance,…

Networking and Internet Architecture · Computer Science 2025-01-22 Khandaker Foysal Haque , Milin Zhang , Francesca Meneghello , Francesco Restuccia

Large Multimodal Models (LMMs) are increasingly capable of answering medical questions that require joint reasoning over images and text, yet training general medical VQA systems is impeded by the lack of large, openly usable, high-quality…

Machine Learning · Computer Science 2026-02-19 Xiaoke Huang , Ningsen Wang , Hui Liu , Xianfeng Tang , Yuyin Zhou

Biological signals, such as electroencephalograms (EEG), play a crucial role in numerous clinical applications, exhibiting diverse data formats and quality profiles. Current deep learning models for biosignals are typically specialized for…

Signal Processing · Electrical Eng. & Systems 2023-05-18 Chaoqi Yang , M. Brandon Westover , Jimeng Sun

Wireless all-analog biosensor design for concurrent microfluidic and physiological signal monitoring is presented in this work. The key component is an all-analog circuit capable of compressing two analog sources into one analog signal by…

Signal Processing · Electrical Eng. & Systems 2019-07-02 Xueyuan Zhao , Vidyasagar Sadhu , Tuan Le , Dario Pompili , Mehdi Javanmard

We have tuned the whispering gallery modes of a fused silica micro- resonator over nearly 1 nm at 800 nm, i.e.over half of a free spectral range or the equivalent of 10^6 linewidths of the resonator.This has been achieved by a new method…

Artefacts compromise clinical decision-making in the use of medical time series. Pulsatile waveforms offer probabilities for accurate artefact detection, yet most approaches rely on supervised manners and overlook patient-level distribution…

Signal Processing · Electrical Eng. & Systems 2025-05-01 Xuhang Chen , Ihsane Olakorede , Stefan Yu Bögli , Wenhao Xu , Erta Beqiri , Xuemeng Li , Chenyu Tang , Zeyu Gao , Shuo Gao , Ari Ercole , Peter Smielewski

Audio watermarking is essential for verifying speech authenticity, yet single-watermark schemes often struggle against sophisticated distortions such as neural reconstruction and adversarial attacks. To address this limitation, we introduce…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-11 Zheqi Yuan , Yucheng Huang , Guangzhi Sun , Zengrui Jin , Chao Zhang

The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

In this paper, the application of hierarchical wireless sensor networks in water quality monitoring is investigated. Adopting a hierarchical structure, the set of sensors is divided into multiple clusters where the value of the sensing…

Signal Processing · Electrical Eng. & Systems 2018-03-13 Ebrahim Karami , Francis M. Bui , Ha H. Nguyen

The interaction of magnetic dipole (MD) emitters and common photonic cavities is usually weak, which is partially due to the low magnetic near field enhancements of the cavities. Here, we show that whispering gallery modes (WGMs) of a…

Optics · Physics 2022-12-07 Ma-Long Hu , Xiao-Jing Du , Lin Ma , Jun He , Zhong-Jian Yang
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