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It has been shown that the adjacency eigenspace of a network contains key information of its underlying structure. However, there has been no study on spectral analysis of the adjacency matrices of directed signed graphs. In this paper, we…

Social and Information Networks · Computer Science 2016-12-28 Yuemeng Li , Xintao Wu , Aidong Lu

Real data collected from different applications that have additional topological structures and connection information are amenable to be represented as a weighted graph. Considering the node labeling problem, Graph Neural Networks (GNNs)…

Social and Information Networks · Computer Science 2020-02-06 Xiaoxiao Li , Joao Saude

Inferring gene regulatory networks is an important problem in systems biology. However, these networks can be hard to infer from experimental data because of the inherent variability in biological data as well as the large number of genes…

Applications · Statistics 2016-03-16 William Chad Young , Ka Yee Yeung , Adrian E. Raftery

The message-passing mechanism underlying Graph Neural Networks (GNNs) is not naturally suited for heterophilic datasets, where adjacent nodes often have different labels. Most solutions to this problem remain confined to the task of node…

Machine Learning · Computer Science 2025-06-30 Andrea Giuseppe Di Francesco , Francesco Caso , Maria Sofia Bucarelli , Fabrizio Silvestri

Hypergraph neural networks can model multi-way connections among nodes of the graphs, which are common in real-world applications such as genetic medicine. In particular, genetic pathways or gene sets encode molecular functions driven by…

Machine Learning · Computer Science 2022-10-17 Yuan Luo

Empirical networked systems are often only partially observed: sampling frames, crawling policies, privacy constraints, and temporal gaps can leave actors and edges unobserved. This complicates robustness and sensitivity analysis because…

Social and Information Networks · Computer Science 2026-05-12 Mehrdad Jalali , Binh Vu , Swati Chandna , Chen Ding

Link prediction on graphs is a fundamental problem. Subgraph representation learning approaches (SGRLs), by transforming link prediction to graph classification on the subgraphs around the links, have achieved state-of-the-art performance…

Machine Learning · Computer Science 2024-10-21 Paul Louis , Shweta Ann Jacob , Amirali Salehi-Abari

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

Machine Learning · Computer Science 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

Graph neural networks (GNNs) have recently been shown to be vulnerable to adversarial attacks, where slight perturbations in the graph structure can lead to erroneous predictions. However, current robust models for defending against such…

Machine Learning · Computer Science 2023-12-15 Ao Liu , Wenshan Li , Tao Li , Beibei Li , Hanyuan Huang , Pan Zhou

Predicting signed interactions in biological networks is crucial for understanding drug mechanisms and facilitating drug repurposing. While deep graph models have demonstrated success in modeling complex biological systems, existing…

Machine Learning · Computer Science 2025-03-19 Shuyi Jin , Mengji Zhang , Meijie Wang , Lun Yu

The increasing penetration of renewable energy sources introduces significant variability and uncertainty in modern power systems, making accurate state prediction critical for reliable grid operation. Conventional forecasting methods often…

Machine Learning · Computer Science 2025-04-01 Dhruv Suri , Mohak Mangal

Network topology inference is a prominent problem in Network Science. Most graph signal processing (GSP) efforts to date assume that the underlying network is known, and then analyze how the graph's algebraic and spectral characteristics…

Signal Processing · Electrical Eng. & Systems 2019-05-22 Gonzalo Mateos , Santiago Segarra , Antonio G. Marques , Alejandro Ribeiro

Graph network science is becoming increasingly popular, notably in big-data perspective where understanding individual entities for individual functional roles is complex and time consuming. It is likely when a set of genes are regulated by…

Genomics · Quantitative Biology 2021-03-11 Abhishek Narain Singh

Signed networks are graphs whose edges are labelled with either a positive or a negative sign, and can be used to capture nuances in interactions that are missed by their unsigned counterparts. The concept of balance in signed graph theory…

Social and Information Networks · Computer Science 2020-02-04 Bruno Ordozgoiti , Antonis Matakos , Aristides Gionis

Traffic forecasting is the foundation for intelligent transportation systems. Spatiotemporal graph neural networks have demonstrated state-of-the-art performance in traffic forecasting. However, these methods do not explicitly model some of…

Machine Learning · Computer Science 2024-03-05 Qipeng Qian , Tanwi Mallick

Efficient and effective drug-target binding affinity (DTBA) prediction is a challenging task due to the limited computational resources in practical applications and is a crucial basis for drug screening. Inspired by the good representation…

Biomolecules · Quantitative Biology 2022-06-15 Shuke Zhang , Yanzhao Jin , Tianmeng Liu , Qi Wang , Zhaohui Zhang , Shuliang Zhao , Bo Shan

Despite theoretical advantages, causal methods for Gene Regulatory Network (GRN) inference from single-cell RNA-seq data consistently fail to match or outperform correlation-based baselines in many realistic benchmarks, a persistent puzzle…

Machine Learning · Computer Science 2026-05-07 Miguel Fernandez-de-Retana , Ruben Sanchez-Corcuera , Unai Zulaika , Aritz Bilbao-Jayo , Aitor Almeida

Learning a graph with a specific structure is essential for interpretability and identification of the relationships among data. It is well known that structured graph learning from observed samples is an NP-hard combinatorial problem. In…

Machine Learning · Statistics 2019-09-26 Sandeep Kumar , Jiaxi Ying , Jos'e Vin'icius de M. Cardoso , Daniel P. Palomar

Learning graph convolutional networks (GCNs) is an emerging field which aims at generalizing convolutional operations to arbitrary non-regular domains. In particular, GCNs operating on spatial domains show superior performances compared to…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Hichem Sahbi

Deciphering complex gene-gene interactions remains challenging in transcriptomics as traditional methods often miss higher-order and nonlinear dependencies. This study introduces a quantum-inspired framework leveraging tensor networks (TNs)…

Molecular Networks · Quantitative Biology 2025-09-09 Olatz Sanz Larrarte , Borja Aizpurua , Reza Dastbasteh , Ruben M. Otxoa , Josu Etxezarreta Martinez