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Graph representation learning (GRL) has emerged as a powerful technique for solving graph analytics tasks. It can effectively convert discrete graph data into a low-dimensional space where the graph structural information and graph…

Social and Information Networks · Computer Science 2023-09-21 Chunyu Miao , Chenxuan Xie , Jiajun Zhou , Shanqing Yu , Lina Chen , Qi Xuan

We explore the feasibility of combining Graph Neural Network-based policy architectures with Deep Reinforcement Learning as an approach to problems in systems. This fits particularly well with operations on networks, which naturally take…

Machine Learning · Computer Science 2021-12-02 Oliver Hope , Eiko Yoneki

In this work, we present a quantum circuit model for inferring gene regulatory networks (GRNs). The model is based on the idea of using qubit-qubit entanglement to simulate interactions between genes. We provide preliminary results that…

Emerging Technologies · Computer Science 2022-07-06 Cristhian Roman-Vicharra , James J. Cai

Graph processes exhibit a temporal structure determined by the sequence index and and a spatial structure determined by the graph support. To learn from graph processes, an information processing architecture must then be able to exploit…

Signal Processing · Electrical Eng. & Systems 2020-12-02 Luana Ruiz , Fernando Gama , Alejandro Ribeiro

Gaussian Graphical Models (GGMs) have been used to construct genetic regulatory networks where regularization techniques are widely used since the network inference usually falls into a high-dimension-low-sample-size scenario. Yet, finding…

Methodology · Statistics 2013-04-24 Shuang Li , Li Hsu , Jie Peng , Pei Wang

The graph neural network (GNN) has demonstrated its superior performance in various applications. The working mechanism behind it, however, remains mysterious. GNN models are designed to learn effective representations for graph-structured…

Machine Learning · Computer Science 2022-06-10 Zepeng Zhang , Ziping Zhao

One of the focus areas of modern scientific research is to reveal mysteries related to genes and their interactions. The dynamic interactions between genes can be encoded into a gene regulatory network (GRN), which can be used to gain…

Optimization and Control · Mathematics 2020-07-16 Atte Aalto , Lauri Viitasaari , Pauliina Ilmonen , Laurent Mombaerts , Jorge Goncalves

Graph Neural Networks (GNNs) have been widely used for various learning tasks, ranging from node classification to link prediction. They have demonstrated excellent performance in multiple domains involving graph-structured data. However,…

Machine Learning · Computer Science 2026-03-19 Steven E. Wilson , Sina Khanmohammadi

Graph Convolutional Networks (GCNs) have been shown to be a powerful concept that has been successfully applied to a large variety of tasks across many domains over the past years. In this work we study the theory that paved the way to the…

Machine Learning · Computer Science 2022-07-13 Matteo Bunino

The evolutionary origins of structural features in reconstructed gene-regulatory networks (GRNs) remain poorly understood, especially given the random aspects of gene expression. Here, we extend a classical model of GRN evolution to allow a…

Populations and Evolution · Quantitative Biology 2026-04-30 Leonardo Ivan Estrella Dzib , James Holehouse

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

Signed graphs, which are characterized by both positive and negative edge weights, have recently attracted significant attention in the field of graph signal processing (GSP). Existing works on signed graph learning typically assume that…

Signal Processing · Electrical Eng. & Systems 2025-09-12 Rong Ye , Xue-Qin Jiang , Hui Feng , Jian Wang , Runhe Qiu

Many scientific and engineering processes produce spatially unstructured data. However, most data-driven models require a feature matrix that enforces both a set number and order of features for each sample. They thus cannot be easily…

Machine Learning · Computer Science 2021-09-30 Francis Ogoke , Kazem Meidani , Amirreza Hashemi , Amir Barati Farimani

It has been estimated that about 30% of the genes in the human genome are regulated by microRNAs (miRNAs). These are short RNA sequences that can down-regulate the levels of mRNAs or proteins in animals and plants. Genes regulated by miRNAs…

Applications · Statistics 2011-01-10 Francesco C. Stingo , Yian A. Chen , Marina Vannucci , Marianne Barrier , Philip E. Mirkes

Link prediction for directed graphs is a crucial task with diverse real-world applications. Recent advances in embedding methods and Graph Neural Networks (GNNs) have shown promising improvements. However, these methods often lack a…

Machine Learning · Computer Science 2025-05-22 Mingguo He , Yuhe Guo , Yanping Zheng , Zhewei Wei , Stephan Günnemann , Xiaokui Xiao

Accurately inferring Gene Regulatory Networks (GRNs) is a critical and challenging task in biology. GRNs model the activatory and inhibitory interactions between genes and are inherently causal in nature. To accurately identify GRNs,…

Signed graphs allow for encoding positive and negative relations between nodes and are used to model various online activities. Node representation learning for signed graphs is a well-studied task with important applications such as sign…

Machine Learning · Computer Science 2024-12-19 Andrin Rehmann , Alexandre Bovet

Graph Convolutional Networks (GCNs) have received increasing attention in the machine learning community for effectively leveraging both the content features of nodes and the linkage patterns across graphs in various applications. As…

Machine Learning · Computer Science 2021-01-01 Donghan Yu , Ruohong Zhang , Zhengbao Jiang , Yuexin Wu , Yiming Yang

Use of computational methods to predict gene regulatory networks (GRNs) from gene expression data is a challenging task. Many studies have been conducted using unsupervised methods to fulfill the task; however, such methods usually yield…

Machine Learning · Computer Science 2016-08-15 Nihir Patel , Jason T. L. Wang