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Interactions between genes and environmental factors may play a key role in the etiology of many common disorders. Several regularized generalized linear models (GLMs) have been proposed for hierarchical selection of gene by environment…

Methodology · Statistics 2023-12-22 Julien St-Pierre , Karim Oualkacha , Julien St-Pierre

Despite strong empirical performance for image classification, deep neural networks are often regarded as ``black boxes'' and they are difficult to interpret. On the other hand, sparse convolutional models, which assume that a signal can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-25 Xili Dai , Mingyang Li , Pengyuan Zhai , Shengbang Tong , Xingjian Gao , Shao-Lun Huang , Zhihui Zhu , Chong You , Yi Ma

Neural Posterior Estimation (NPE) enables rapid parameter inference for complex simulators with intractable likelihoods. NPE trains an inference network to estimate a probability density over parameters given data, typically assumed to be…

Machine Learning · Computer Science 2026-05-14 Jan Boelts , Cornelius Schröder , Jonas Beck , Jakob H. Macke , Michael Deistler , Daniel Gedon

Hyperspectral image (HSI) classification typically involves large-scale data and computationally intensive training, which limits the practical deployment of deep learning models in real-world remote sensing tasks. This study introduces…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Meihua Zhou , Liping Yu , Xinyu Tong , Wai Kin Fung , Ruiguo Hu , Jiarui Zhao , Wenzhuo Liu , Nan Wan

We consider the complex data modeling problem motivated by the zero-inflated and overdispersed data from microbiome studies. Analyzing how microbiome abundance is associated with human biological features, such as BMI, is of great…

Methodology · Statistics 2025-03-31 Zirui Wang , Tianying Wang

Mechanistic interpretability is an emerging diagnostic approach for neural models that has gained traction in broader natural language processing domains. This paradigm aims to provide attribution to components of neural systems where…

Information Retrieval · Computer Science 2025-01-20 Andrew Parry , Catherine Chen , Carsten Eickhoff , Sean MacAvaney

We motivate weakly supervised learning as an effective learning paradigm for problems where curating perfectly annotated datasets is expensive and may require domain expertise such as fine-grained classification. We focus on Partial Label…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Darshana Saravanan , Naresh Manwani , Vineet Gandhi

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…

Machine Learning · Computer Science 2024-11-21 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

The multiscale and turbulent nature of Earth's atmosphere has historically rendered accurate weather modeling a hard problem. Recently, there has been an explosion of interest surrounding data-driven approaches to weather modeling, which in…

Geophysics · Physics 2025-07-08 Seth Minor , Daniel A. Messenger , Vanja Dukic , David M. Bortz

I consider inference in a partially linear regression model under stationary $\beta$-mixing data after first stage deep neural network (DNN) estimation. Using the DNN results of Brown (2024), I show that the estimator for the finite…

Econometrics · Economics 2024-10-31 Chad Brown

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris

Deep learning with noisy labels is a challenging task. Recent prominent methods that build on a specific sample selection (SS) strategy and a specific semi-supervised learning (SSL) model achieved state-of-the-art performance. Intuitively,…

Machine Learning · Computer Science 2020-12-03 Zhuowei Wang , Jing Jiang , Bo Han , Lei Feng , Bo An , Gang Niu , Guodong Long

Single image super-resolution (SR) is an ill-posed problem which aims to recover high-resolution (HR) images from their low-resolution (LR) observations. The crux of this problem lies in learning the complex mapping between low-resolution…

Computer Vision and Pattern Recognition · Computer Science 2017-01-05 Ding Liu , Zhaowen Wang , Nasser Nasrabadi , Thomas Huang

An important feature of successful supervised machine learning applications is to be able to explain the predictions given by the regression or classification model being used. However, most state-of-the-art models that have good predictive…

Machine Learning · Statistics 2019-10-14 Victor Coscrato , Marco Henrique de Almeida Inácio , Tiago Botari , Rafael Izbicki

The interpretability of models has become a crucial issue in Machine Learning because of algorithmic decisions' growing impact on real-world applications. Tree ensemble methods, such as Random Forests or XgBoost, are powerful learning tools…

Optimization and Control · Mathematics 2024-01-19 Giulia Di Teodoro , Marta Monaci , Laura Palagi

This work demonstrates the Python package mlreflect which implements an optimized pipeline for the automized analysis of reflectometry data using machine learning. The package combines several training and data treatment techniques…

The field of computational pathology has witnessed great advancements since deep neural networks have been widely applied. These networks usually require large numbers of annotated data to train vast parameters. However, it takes…

Computer Vision and Pattern Recognition · Computer Science 2022-08-11 Yixiao Zhang , Adam Kortylewski , Qing Liu , Seyoun Park , Benjamin Green , Elizabeth Engle , Guillermo Almodovar , Ryan Walk , Sigfredo Soto-Diaz , Janis Taube , Alex Szalay , Alan Yuille

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Plants in their natural habitats endure an array of interacting stresses, both biotic and abiotic, that rarely occur in isolation. Nutrient stress-particularly nitrogen deficiency-becomes even more critical when compounded with drought and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Aswini Kumar Patra , Lingaraj Sahoo