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Related papers: Optimizing infectious disease mitigation under dyn…

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We study equilibrium distancing during epidemics. Distancing reduces the individual's probability of getting infected but comes at a cost. It creates a single-peaked epidemic, flattens the curve and decreases the size of the epidemic. We…

General Economics · Economics 2021-03-02 Satoshi Fukuda , Nenad Kos , Christoph Wolf

In many epidemiological and ecological contexts, there is a trade-off between infections and interactions. This arises because the links between individuals capable of spreading infections are also often associated with beneficial…

Physics and Society · Physics 2025-04-04 Bunlang Thatchai , Christopher E. Overton , Thomas House

Social dilemmas where the good of a group is at odds with individual interests are usually considered as static -- the dilemma does not change over time. In the COVID-19 pandemic, social dilemmas occurred in the mitigation of epidemic…

Physics and Society · Physics 2024-10-31 Lucas S. Flores , Amanda de Azevedo-Lopes , Chadi M. Saad-Roy , Arne Traulsen

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Applications · Statistics 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

This paper combines a canonical epidemiology model of disease dynamics with government policy of lockdown and testing, and agents' decision to social distance in order to avoid getting infected. The model is calibrated with data on deaths…

General Economics · Economics 2022-02-10 Shomak Chakrabarti , Ilia Krasikov , Rohit Lamba

The isolation of infectious individuals is a key measure of public health for the control of communicable diseases. However, involving a strong perturbation of daily life, it often causes psychosocial distress, and severe financial and…

Physics and Society · Physics 2021-11-09 Giulia de Meijere , Vittoria Colizza , Eugenio Valdano , Claudio Castellano

Several recent studies have tackled the issue of optimal network immunization by providing efficient criteria to identify key nodes to be removed in order to break apart a network, thus preventing the occurrence of extensive epidemic…

Physics and Society · Physics 2018-02-22 Giovanni Strona , Claudio Castellano

In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…

Populations and Evolution · Quantitative Biology 2021-04-22 Dylan H. Morris , Fernando W. Rossine , Joshua B. Plotkin , Simon A. Levin

Non-pharmaceutical interventions (NPIs) are crucial for controlling pandemics, but existing research often overlooks the heterogeneity of individual behavior, which can lead to inaccurate evaluations of the effectiveness of strategies. In…

Physics and Society · Physics 2026-03-09 Xihan Zhang , Yuqing Liu , Chen Zhao , Guijun Li

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

Machine Learning · Computer Science 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

Major advances in public health have resulted from disease prevention. However, prevention of a new infectious disease by vaccination or pharmaceuticals is made difficult by the slow process of vaccine and drug development. We propose an…

Populations and Evolution · Quantitative Biology 2021-04-15 Jussi Taipale , Ioannis Kontoyiannis , Sten Linnarsson

For centuries isolation has been the main control strategy of unforeseen epidemic outbreaks. When implemented in full and without delay, isolation is very effective. However, flawless implementation is seldom feasible in practice. We…

Populations and Evolution · Quantitative Biology 2019-01-23 Lai-Sang Young , Stefan Ruschel , Serhiy Yanchuk , Tiago Pereira

Masks have remained an important mitigation strategy in the fight against COVID-19 due to their ability to prevent the transmission of respiratory droplets between individuals. In this work, we provide a comprehensive quantitative analysis…

Social and Information Networks · Computer Science 2023-08-02 Yurun Tian , Anirudh Sridhar , Chai Wah Wu , Simon A. Levin , Kathleen M. Carley , H. Vincent Poor , Osman Yagan

Without vaccines and treatments, societies must rely on non-pharmaceutical intervention strategies to control the spread of emerging diseases such as COVID-19. Though complete lockdown is epidemiologically effective, because it eliminates…

Populations and Evolution · Quantitative Biology 2021-01-08 Jason Hindes , Simone Bianco , Ira B. Schwartz

Optimal control of interdependent epidemics spreading over complex networks is a critical issue. We first establish a framework to capture the coupling between two epidemics, and then analyze the system's equilibrium states by categorizing…

Systems and Control · Computer Science 2017-10-19 Juntao Chen , Rui Zhang , Quanyan Zhu

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

Populations and Evolution · Quantitative Biology 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

Restrictions on social and economic activities, as well as vaccinations, have been a key intervention in containing the COVID-19 epidemic. Our work focuses on better understanding the options available to policymakers under the conditions…

Optimization and Control · Mathematics 2023-09-07 Franco Galante , Chiara Ravazzi , Michele Garetto , Emilio Leonardi

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

This paper investigates the optimal control of an epidemic governed by a SEIR model with an operational delay in vaccination. We address the mathematical challenge of imposing hard healthcare capacity constraints (e.g., ICU limits) over an…

Optimization and Control · Mathematics 2026-03-16 Behrooz Moosavi Ramezanzadeh

Infectious diseases are among the most prominent threats to mankind. When preventive health care cannot be provided, a viable means of disease control is the isolation of individuals, who may be infected. To study the impact of isolation,…

Dynamical Systems · Mathematics 2018-04-10 Stefan Ruschel , Tiago Pereira , Serhiy Yanchuk , Lai-Sang Young