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The metabolism is the motor behind the biological complexity of an organism. One problem of characterizing its large-scale structure is that it is hard to know what to compare it to. All chemical reaction systems are shaped by the same…

Molecular Networks · Quantitative Biology 2011-05-10 Petter Holme , Mikael Huss , Sang Hoon Lee

Decomposition of biomolecular reaction networks into pathways is a powerful approach to the analysis of metabolic and signalling networks. Current approaches based on analysis of the stoichiometric matrix reveal information about…

Molecular Networks · Quantitative Biology 2018-08-14 Peter J. Gawthrop , Edmund J. Crampin

Template tasks have emerged as a clean testbed for asking whether transformers reason with abstract symbols rather than concrete token names. We study the fixed-label classification version of this problem, where train and test examples…

Machine Learning · Computer Science 2026-05-11 Wenjie Guan , Jelena Bradic

In density functional theory, charge density is the core attribute of atomic systems from which all chemical properties can be derived. Machine learning methods are promising in significantly accelerating charge density prediction, yet…

Computational Physics · Physics 2024-05-30 Xiang Fu , Andrew Rosen , Kyle Bystrom , Rui Wang , Albert Musaelian , Boris Kozinsky , Tess Smidt , Tommi Jaakkola

The Connectivity Map (CMap) is a large publicly available database of cellular transcriptomic responses to chemical and genetic perturbations built using a standardized acquisition protocol known as the L1000 technique. Databases such as…

Quantitative Methods · Quantitative Biology 2024-05-01 Steven Shave , Richard Kasprowicz , Abdullah M. Athar , Denise Vlachou , Neil O. Carragher , Cuong Q. Nguyen

We present herein an extension of an algebraic statistical method for inferring biochemical reaction networks from experimental data, proposed recently in [3]. This extension allows us to analyze reaction networks that are not necessarily…

Molecular Networks · Quantitative Biology 2009-02-26 Gheorghe Craciun , Casian Pantea , Grzegorz A. Rempala

We present a microscopic model for systems showing resistivity saturation. An essentially exact quantum Monte-Carlo calculation demonstrates that the model describes saturation. We give a simple explanation for saturation, using charge…

Materials Science · Physics 2009-11-07 M. Calandra , O. Gunnarsson

Chemical disorder, originating from the mixed occupation of crystallographic sites by multiple elements, is widespread in alloys, ceramics, and compositionally complex materials, where short- and long-range orderings can strongly influence…

Materials Science · Physics 2026-05-20 Jiayu Peng , Peichen Zhong

Understanding the structural complexity and predictability of complex networks is a central challenge in network science. Although recent studies have revealed a relationship between compression-based entropy and link prediction…

Social and Information Networks · Computer Science 2025-10-14 Sebastián Brzovic , Cristóbal Rojas , Andrés Abeliuk

Thermodynamic constraints on reactions directions are inherent in the structure of a given biochemical network. However, concrete procedures for determining feasible reaction directions for large-scale metabolic networks are not well…

Molecular Networks · Quantitative Biology 2007-05-23 Feng Yang , Feng Qi , Daniel A. Beard

Graph neural networks have recently become a standard method for analysing chemical compounds. In the field of molecular property prediction, the emphasis is now put on designing new model architectures, and the importance of atom…

Chemical Physics · Physics 2021-02-15 Agnieszka Pocha , Tomasz Danel , Łukasz Maziarka

Named entity recognition is a fundamental task in natural language processing, identifying the span and category of entities in unstructured texts. The traditional sequence labeling methodology ignores the nested entities, i.e. entities…

Computation and Language · Computer Science 2022-10-24 Xueru Wen , Changjiang Zhou , Haotian Tang , Luguang Liang , Yu Jiang , Hong Qi

In this work we consider the task of relaxing the i.i.d assumption in pattern recognition (or classification), aiming to make existing learning algorithms applicable to a wider range of tasks. Pattern recognition is guessing a discrete…

Machine Learning · Computer Science 2012-02-28 Daniil Ryabko

Modern materials science has historically been founded on combining restricted subsets of the periodic table, favoring high-purity, few-element systems. However, the demands of an emerging circular economy, together with the need to…

Materials Science · Physics 2026-03-02 Anton Bochkarev , Yury Lysogorskiy , Aparna Subramanyam , Ralf Drautz , Danny Perez

Predicting relaxed atomic structures of chemically complex materials remains a major computational challenge, particularly for high-entropy systems where traditional first-principles methods become prohibitively expensive. We introduce the…

Disordered Systems and Neural Networks · Physics 2025-12-09 Neethu Mohan Mangalassery , Abhishek Kumar Singh

The use of machine learning is becoming increasingly common in computational materials science. To build effective models of the chemistry of materials, useful machine-based representations of atoms and their compounds are required. We…

Materials Science · Physics 2021-08-02 Luis M. Antunes , Ricardo Grau-Crespo , Keith T. Butler

Computational techniques are required for narrowing down the vast space of possibilities to plausible prebiotic scenarios, since precise information on the molecular composition, the dominant reaction chemistry, and the conditions for that…

Molecular Networks · Quantitative Biology 2018-02-07 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

Accurate prediction of the physicochemical properties of molecular mixtures using graph neural networks remains a significant challenge, as it requires simultaneous embedding of intramolecular interactions while accounting for mixture…

Chemical Physics · Physics 2026-03-04 Jinming Fan , Chao Qian , Wilhelm T. S. Huck , William E. Robinson , Shaodong Zhou

In Multi-Label Text Classification (MLTC), one sample can belong to more than one class. It is observed that most MLTC tasks, there are dependencies or correlations among labels. Existing methods tend to ignore the relationship among…

Computation and Language · Computer Science 2020-03-27 Ankit Pal , Muru Selvakumar , Malaikannan Sankarasubbu

We define a mapping from transition-based parsing algorithms that read sentences from left to right to sequence labeling encodings of syntactic trees. This not only establishes a theoretical relation between transition-based parsing and…

Computation and Language · Computer Science 2020-11-03 Carlos Gómez-Rodríguez , Michalina Strzyz , David Vilares