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Spatio-temporal network dynamics is an emergent property of many complex systems which remains poorly understood. We suggest a new approach to its study based on the analysis of dynamical motifs -- small subnetworks with periodic and…

Disordered Systems and Neural Networks · Physics 2007-05-23 Valentin P. Zhigulin

Networks are fundamental for our understanding of complex systems. Interactions between individual nodes in networks generate network motifs - small recurrent patterns that can be considered the network's building-block components,…

Dynamical Systems · Mathematics 2022-09-14 Miri Adler , Ruslan Medzhitov

Complex networks evolve and vary their structure as time goes by. In particular, the links in those networks have both a sign and a directionality. To understand their structural principles, we measure the network motifs, which are patterns…

Physics and Society · Physics 2023-06-28 Youngjai Park , Mi Jin Lee , Seung-Woo Son

Understanding why some cellular components are conserved across species, while others evolve rapidly is a key question of modern biology. Here we demonstrate that in S. cerevisiae proteins organized in cohesive patterns of interactions are…

Genomics · Quantitative Biology 2007-05-23 S. Wuchty , Z. N. Oltvai , A. -L. Barabasi

Network science can offer fundamental insights into the structural and functional properties of complex systems. For example, it is widely known that neuronal circuits tend to organize into basic functional topological modules, called…

Adaptation and Self-Organizing Systems · Physics 2022-08-03 Matteo Zambra , Alberto Testolin , Amos Maritan

Network motifs can capture basic interaction patterns and inform the functional properties of networks. However, real-world complex systems often have multiple types of relationships, which cannot be represented by a monolayer network. The…

Physics and Society · Physics 2019-03-06 Lu Zhong , Qingpeng Zhang , Dong Yang , Guanrong Chen , Shi Yu

A deluge of new data on social, technological and biological networked systems suggests that a large number of interactions among system units are not limited to pairs, but rather involve a higher number of nodes. To properly encode such…

Physics and Society · Physics 2023-11-08 Quintino Francesco Lotito , Federico Musciotto , Alberto Montresor , Federico Battiston

One of the most important concepts in biological network analysis is that of network motifs, which are patterns of interconnections that occur in a given network at a frequency higher than expected in a random network. In this work we are…

Discrete Mathematics · Computer Science 2020-05-29 Diego P Rubert , Eloi Araujo , Marco A Stefanes , Jens Stoye , Fábio V Martinez

Motifs are the fundamental components of complex systems. The topological structure of networks representing complex systems and the frequency and distribution of motifs in these networks are intertwined. The complexities associated with…

Social and Information Networks · Computer Science 2020-05-21 Ali Jazayeri , Christopher C. Yang

Self-organisation of individuals within large collectives occurs throughout biology. Mathematical models can help elucidate the individual-level mechanisms behind these dynamics, but analytical tractability often comes at the cost of…

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

Many real-world phenomena are best represented as interaction networks with dynamic structures (e.g., transaction networks, social networks, traffic networks). Interaction networks capture flow of data which is transferred between their…

Social and Information Networks · Computer Science 2018-10-22 Chrysanthi Kosyfaki , Nikos Mamoulis , Evaggelia Pitoura , Panayiotis Tsaparas

Network motifs are characteristic patterns which occur in the networks essentially more frequently than the other patterns. For five motifs found in S. Itzkovitz, U. Alon, Phys. Rev.~E, 2005, 71, 026117-1, hierarchical random graphs are…

Mathematical Physics · Physics 2015-04-02 Monika Kotorowicz , Yuri Kozitsky

Interconnected ensembles of biological entities are perhaps some of the most complex systems that modern science has encountered so far. In particular, scientists have concentrated on understanding how the complexity of the interacting…

Pattern Formation and Solitons · Physics 2020-11-18 Bram A. Siebert , Cameron L. Hall , James P. Gleeson , Malbor Asllani

Several natural and theoretical networks can be broken down into smaller portions, or subgraphs corresponding to neighborhoods. The more frequent of these neighborhoods can then be understood as motifs of the network, being therefore…

Physics and Society · Physics 2022-04-21 Guilherme S. Domingues , Eric K. Tokuda , Luciano da F. Costa

The search for patterns or motifs in data represents an area of key interest to many researchers. In this paper we present the Motif Tracking Algorithm, a novel immune inspired pattern identification tool that is able to identify unknown…

Artificial Intelligence · Computer Science 2010-07-05 William O. Wilson , Jan Feyereisl , Uwe Aickelin

Network motifs are recurrent, small-scale patterns of interactions observed frequently in a system. They shed light on the interplay between the topology and the dynamics of complex networks across various domains. In this work, we focus on…

Social and Information Networks · Computer Science 2023-11-08 Quintino Francesco Lotito , Federico Musciotto , Federico Battiston , Alberto Montresor

Particles that are catalytically-active and chemotactic can interact through the concentration fields upon which they act, which in turn may lead to wide-scale spatial self-organization. When these active particles interact through several…

Soft Condensed Matter · Physics 2023-10-12 Vincent Ouazan-Reboul , Ramin Golestanian , Jaime Agudo-Canalejo

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

Populations and Evolution · Quantitative Biology 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

During development, highly ordered structures emerge as cells collectively coordinate with each other. While recent advances have clarified how individual cells process and respond to external signals, understanding collective cellular…

Biological Physics · Physics 2026-02-05 Ashutosh Tripathi , Jörn Dunkel , Dominic J. Skinner
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