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Breast cancer is one of the leading fatal disease worldwide with high risk control if early discovered. Conventional method for breast screening is x-ray mammography, which is known to be challenging for early detection of cancer lesions.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Essam A. Rashed , M. Samir Abou El Seoud

Breast cancer is one of the leading causes of cancer-related mortality in women, and early detection is essential for improving outcomes. Magnetic resonance imaging (MRI) is a highly sensitive tool for breast cancer detection, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Smriti Joshi , Lidia Garrucho , Richard Osuala , Oliver Diaz , Karim Lekadir

Convolution Neural Networks (CNNs) are widely used in medical image analysis, but their performance degrade when the magnification of testing images differ from the training images. The inability of CNNs to generalize across magnification…

Image and Video Processing · Electrical Eng. & Systems 2023-02-23 Pranav Jeevan , Nikhil Cherian Kurian , Amit Sethi

Persistent homology is an effective method for extracting topological information, represented as persistent diagrams, of spatial structure data. Hence it is well-suited for the study of protein structures. Attempts to incorporate…

Machine Learning · Computer Science 2024-08-01 An Wu , Yu Pan , Fuqi Zhou , Jinghui Yan , Chuanlu Liu

Optimization, a key tool in machine learning and statistics, relies on regularization to reduce overfitting. Traditional regularization methods control a norm of the solution to ensure its smoothness. Recently, topological methods have…

Machine Learning · Computer Science 2020-11-11 Arnur Nigmetov , Aditi S. Krishnapriyan , Nicole Sanderson , Dmitriy Morozov

Breast cancer is one of the main causes of death worldwide. Histopathological cellularity assessment of residual tumors in post-surgical tissues is used to analyze a tumor's response to a therapy. Correct cellularity assessment increases…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Alexander Rakhlin , Aleksei Tiulpin , Alexey A. Shvets , Alexandr A. Kalinin , Vladimir I. Iglovikov , Sergey Nikolenko

Annotating medical images demands significant time and expertise, often requiring pathologists to invest hundreds of hours in labeling mammary epithelial nuclei datasets. We address this critical challenge by achieving 95.5% Dice score…

Artificial Intelligence · Computer Science 2025-12-03 Varun Kumar Dasoju , Qingsu Cheng , Zeyun Yu

Microcalcifications in mammogram have been mainly targeted as a reliable earliest sign of breast cancer and their early detection is vital to improve its prognosis. Since their size is very small and may be easily overlooked by the…

Computer Vision and Pattern Recognition · Computer Science 2010-02-11 T. Balakumaran , I. L. A. Vennila , C. Gowri Shankar

Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Aleksandar Vakanski , Min Xian , Phoebe Freer

Breast cancer ranks as the most prevalent form of cancer diagnosed in women, and diagnosis faces several challenges, a change in the size, shape and appearance of breasts, dense breast tissue, lumps or thickening in the breast especially if…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Abdulqader Mohammed , Mohammed Abdel Razek , Mohamed El-dosuky , Ahmed Sobhi

Deep learning object detection algorithm has been widely used in medical image analysis. Currently all the object detection tasks are based on the data annotated with object classes and their bounding boxes. On the other hand, medical…

Computer Vision and Pattern Recognition · Computer Science 2020-03-04 Li Xiao , Cheng Zhu , Junjun Liu , Chunlong Luo , Peifang Liu , Yi Zhao

Breast cancer is one of the most common causes of death among women worldwide, with millions of fatalities annually. Magnetic Resonance Imaging (MRI) can provide various sequences for characterizing tumor morphology and internal patterns,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Jingxing Zhong , Qingtao Pan , Xuchang Zhou , Jiazhen Lin , Xinguo Zhuang

We present a machine learning approach that leverages persistent homology to classify bacterial flagellar motors into two functional states: rotated and stalled. By embedding protein structural data into a topological framework, we extract…

Biomolecules · Quantitative Biology 2025-12-19 Zakaria Lamine , Abdelatif Hafid , Mohamed Rahouti

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Introduction: In sodium (23Na) magnetic resonance imaging (MRI), partial volume effects (PVE) are one of the most common causes of errors in the in vivo quantification of tissue sodium concentration (TSC). Advanced image reconstruction…

With respect to spatial overlap, CNN-based segmentation of short axis cardiovascular magnetic resonance (CMR) images has achieved a level of performance consistent with inter observer variation. However, conventional training procedures…

Image and Video Processing · Electrical Eng. & Systems 2020-08-24 Nick Byrne , James R. Clough , Giovanni Montana , Andrew P. King

Accurate identification of breast masses is crucial in diagnosing breast cancer; however, it can be challenging due to their small size and being camouflaged in surrounding normal glands. Worse still, it is also expensive in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Churan Wang , Wenxue Li , Guanbin Li

Recently, deep learning models have shown the potential to predict breast cancer risk and enable targeted screening strategies, but current models do not consider the change in the breast over time. In this paper, we present a new method,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Hyeonsoo Lee , Junha Kim , Eunkyung Park , Minjeong Kim , Taesoo Kim , Thijs Kooi

Achieving health equity in Artificial Intelligence (AI) requires diagnostic models that maintain reliability across diverse populations. However, breast cancer screening systems frequently suffer from domain overfitting, degrading…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Hung Q. Vo , Samira Zare , Son T. Ly , Lin Wang , Chika F. Ezeana , Xiaohui Yu , Kelvin K. Wong , Stephen T. C. Wong , Hien V. Nguyen
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