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The discovery of novel inhibitor molecules for emerging drug-target proteins is widely acknowledged as a challenging inverse design problem: Exhaustive exploration of the vast chemical search space is impractical, especially when the target…

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has emphasized the importance and challenges of correctly interpreting antibody test results. Identification of positive and negative samples requires a…

Quantitative Methods · Quantitative Biology 2023-04-26 Rayanne A. Luke , Anthony J. Kearsley , Nora Pisanic , Yukari C. Manabe , David L. Thomas , Christopher D. Heaney , Paul N. Patrone

The unprecedented outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), or COVID-19, continues to be a significant worldwide problem. As a result, a surge of new COVID-19 related research has followed suit. The growing…

Machine Learning · Computer Science 2021-07-21 Maksim E. Eren , Nick Solovyev , Chris Hamer , Renee McDonald , Boian S. Alexandrov , Charles Nicholas

Node classification in structural networks has been proven to be useful in many real world applications. With the development of network embedding, the performance of node classification has been greatly improved. However, nearly all the…

Social and Information Networks · Computer Science 2021-04-13 Jia-Nan Guo , Xian-Ling Mao , Shu-Yang Lin , Wei Wei , Heyan Huang

COVID-19 (coronavirus disease 2019) pandemic caused by SARS-CoV-2 has led to a treacherous and devastating catastrophe for humanity. At the time of writing, no specific antivirus drugs or vaccines are recommended to control infection…

Machine Learning · Computer Science 2020-10-13 Ankit Pal , Malaikannan Sankarasubbu

Code retrieval, which retrieves code snippets based on users' natural language descriptions, is widely used by developers and plays a pivotal role in real-world software development. The advent of deep learning has shifted the retrieval…

Software Engineering · Computer Science 2024-12-17 Wenchao Gu , Ensheng Shi , Yanlin Wang , Lun Du , Shi Han , Hongyu Zhang , Dongmei Zhang , Michael R. Lyu

The SARS-CoV-2 pandemic has added new urgency to the study of viral mechanisms of infection. But while vaccines offer a measure of protection against this specific outbreak, a new era of pandemics has been predicted. In addition to this,…

Biological Physics · Physics 2022-10-25 Betony Adams , Ilya Sinayskiy , Rienk van Grondelle , Francesco Petruccione

Graph embedding provides a feasible methodology to conduct pattern classification for graph-structured data by mapping each data into the vectorial space. Various pioneering works are essentially coding method that concentrates on a…

Machine Learning · Computer Science 2022-10-04 Xue Liu , Dan Sun , Xiaobo Cao , Hao Ye , Wei Wei

COVID-19 infection caused by SARS-CoV-2 pathogen is a catastrophic pandemic outbreak all over the world with exponential increasing of confirmed cases and, unfortunately, deaths. In this work we propose an AI-powered pipeline, based on the…

In this worldwide spread of SARS-CoV-2 (COVID-19) infection, it is of utmost importance to detect the disease at an early stage especially in the hot spots of this epidemic. There are more than 110 Million infected cases on the globe,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 Sohail Iqbal , H. Fareed Ahmed , Talha Qaiser , Muhammad Imran Qureshi , Nasir Rajpoot

Modern deep learning models capture the semantics of complex data by transforming them into high-dimensional embedding vectors. Emerging applications, such as retrieval-augmented generation, use approximate nearest neighbor (ANN) search in…

Databases · Computer Science 2025-10-01 Guoyu Hu , Shaofeng Cai , Tien Tuan Anh Dinh , Zhongle Xie , Cong Yue , Gang Chen , Beng Chin Ooi

Bayesian phylogenetics is vital for understanding evolutionary dynamics, and requires accurate and efficient approximation of posterior distributions over trees. In this work, we develop a variational Bayesian approach for ultrametric…

Machine Learning · Statistics 2026-02-16 Evan Sidrow , Alexandre Bouchard-Côté , Lloyd T. Elliott

Distributed approaches based on the map-reduce programming paradigm have started to be proposed in the bioinformatics domain, due to the large amount of data produced by the next-generation sequencing techniques. However, the use of…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-05 Umberto Ferraro Petrillo , Mara Sorella , Giuseppe Cattaneo , Raffaele Giancarlo , Simona Rombo

In contrast to regular (simple) networks, hyper networks possess the ability to depict more complex relationships among nodes and store extensive information. Such networks are commonly found in real-world applications, such as in social…

Social and Information Networks · Computer Science 2023-11-08 Shu Liu , Cameron Lai , Fujio Toriumi

Malware classification is an important and challenging problem in information security. Modern malware classification techniques rely on machine learning models that can be trained on features such as opcode sequences, API calls, and byte…

Cryptography and Security · Computer Science 2021-03-05 Aparna Sunil Kale , Fabio Di Troia , Mark Stamp

Confronting the pandemic of COVID-19, is nowadays one of the most prominent challenges of the human species. A key factor in slowing down the virus propagation is the rapid diagnosis and isolation of infected patients. The standard method…

Image and Video Processing · Electrical Eng. & Systems 2021-04-27 Eduardo Luz , Pedro Lopes Silva , Rodrigo Silva , Ludmila Silva , Gladston Moreira , David Menotti

Wastewater based epidemiology is recognized as one of the monitoring pillars, providing essential information for pandemic management. Central in the methodology are data modelling concepts for both communicating the monitoring results but…

Applications · Statistics 2022-08-30 Wolfgang Rauch , Hannes Schenk , Heribert Insam , Rudolf Markt , Norbert Kreuzinger

Since the onset of the COVID-19 pandemic in 2020, millions of people have succumbed to this deadly virus. Many attempts have been made to devise an automated method of testing that could detect the virus. Various researchers around the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Samyak Prajapati , Japman Singh Monga , Shaanya Singh , Amrit Raj , Yuvraj Singh Champawat , Chandra Prakash

This paper demonstrates the utility of organized numerical representations of genes in research involving flat string gene formats (i.e., FASTA/FASTQ5). FASTA/FASTQ files have several current limitations, such as their large file sizes,…

Genomics · Quantitative Biology 2023-08-11 Daniel H. Um , David A. Knowles , Gail E. Kaiser

Timely and rapid diagnoses are core to informing on optimum interventions that curb the spread of COVID-19. The use of medical images such as chest X-rays and CTs has been advocated to supplement the Reverse-Transcription Polymerase Chain…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Ogechukwu Ukwandu , Hanan Hindy , Elochukwu Ukwandu