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Extracting insight from the enormous quantity of data generated from molecular simulations requires the identification of a small number of collective variables whose corresponding low-dimensional free-energy landscape retains the essential…

Chemical Physics · Physics 2019-12-30 Yasemin Bozkurt Varolgunes , Tristan Bereau , Joseph F. Rudzinski

We present a deep-learning Variational Encoder-Decoder (VED) framework for learning data-driven low-dimensional representations of the relationship between high-dimensional parameters of a physical system and the system's high-dimensional…

Machine Learning · Computer Science 2024-12-09 Subashree Venkatasubramanian , David A. Barajas-Solano

Complex multivariate time series arise in many fields, ranging from computer vision to robotics or medicine. Often we are interested in the independent underlying factors that give rise to the high-dimensional data we are observing. While…

Machine Learning · Statistics 2021-02-11 Simon Bing , Vincent Fortuin , Gunnar Rätsch

Variational Autoencoders (VAEs) are powerful generative models capable of learning compact latent representations. However, conventional VAEs often generate relatively blurry images due to their assumption of an isotropic Gaussian latent…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Andrew Kiruluta

We propose a molecular generative model based on the conditional variational autoencoder for de novo molecular design. It is specialized to control multiple molecular properties simultaneously by imposing them on a latent space. As a proof…

Machine Learning · Computer Science 2018-06-18 Jaechang Lim , Seongok Ryu , Jin Woo Kim , Woo Youn Kim

Generative modeling for tabular data has recently gained significant attention in the Deep Learning domain. Its objective is to estimate the underlying distribution of the data. However, estimating the underlying distribution of tabular…

Machine Learning · Computer Science 2024-12-10 Aníbal Silva , André Restivo , Moisés Santos , Carlos Soares

In this work we introduce an Autoencoder for molecular conformations. Our proposed model converts the discrete spatial arrangements of atoms in a given molecular graph (conformation) into and from a continuous fixed-sized latent…

Machine Learning · Computer Science 2021-01-06 Robin Winter , Frank Noé , Djork-Arné Clevert

Representing 3D shape is a fundamental problem in artificial intelligence, which has numerous applications within computer vision and graphics. One avenue that has recently begun to be explored is the use of latent representations of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Tristan Aumentado-Armstrong , Stavros Tsogkas , Allan Jepson , Sven Dickinson

Deep generative models have demonstrated successful applications in learning non-linear data distributions through a number of latent variables and these models use a nonlinear function (generator) to map latent samples into the data space.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Pourya Shamsolmoali , Masoumeh Zareapoor , Huiyu Zhou , Dacheng Tao , Xuelong Li

We report a deep learning (DL) framework viz. deep autoencoder that autonomously discovers an appropriate order parameter from molecular dynamics (MD) simulation data to characterize the coil to globule phase transition of a polymer. The…

Materials Science · Physics 2021-02-25 Debjyoti Bhattacharya , Tarak K Patra

We present a novel deep generative model based on non i.i.d. variational autoencoders that captures global dependencies among observations in a fully unsupervised fashion. In contrast to the recent semi-supervised alternatives for global…

Machine Learning · Computer Science 2020-12-17 Ignacio Peis , Pablo M. Olmos , Antonio Artés-Rodríguez

In audio processing applications, the generation of expressive sounds based on high-level representations demonstrates a high demand. These representations can be used to manipulate the timbre and influence the synthesis of creative…

Sound · Computer Science 2023-01-19 Anastasia Natsiou , Luca Longo , Sean O'Leary

Deep generative models have been praised for their ability to learn smooth latent representation of images, text, and audio, which can then be used to generate new, plausible data. However, current generative models are unable to work with…

Machine Learning · Computer Science 2019-09-09 Bidisha Samanta , Abir De , Gourhari Jana , Pratim Kumar Chattaraj , Niloy Ganguly , Manuel Gomez-Rodriguez

This paper presents a novel decoder-based approach for generating manufacturable 3D structures optimized for additive manufacturing. We introduce a deep learning framework that decodes latent representations into geometrically valid,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Abhishek Kumar

Generative modeling of high-dimensional data is a key problem in machine learning. Successful approaches include latent variable models and autoregressive models. The complementary strengths of these approaches, to model global and local…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Thomas Lucas , Jakob Verbeek

Representation learning for text via pretraining a language model on a large corpus has become a standard starting point for building NLP systems. This approach stands in contrast to autoencoders, also trained on raw text, but with the…

Computation and Language · Computer Science 2021-09-14 Ivan Montero , Nikolaos Pappas , Noah A. Smith

We present an autoencoder that leverages learned representations to better measure similarities in data space. By combining a variational autoencoder with a generative adversarial network we can use learned feature representations in the…

Machine Learning · Computer Science 2016-02-12 Anders Boesen Lindbo Larsen , Søren Kaae Sønderby , Hugo Larochelle , Ole Winther

Physics-constrained data-driven computing is an emerging computational paradigm that allows simulation of complex materials directly based on material database and bypass the classical constitutive model construction. However, it remains…

Numerical Analysis · Mathematics 2022-09-12 Xiaolong He , Qizhi He , Jiun-Shyan Chen

We present a framework for learning disentangled and interpretable jointly continuous and discrete representations in an unsupervised manner. By augmenting the continuous latent distribution of variational autoencoders with a relaxed…

Machine Learning · Statistics 2018-10-23 Emilien Dupont

We present AstroVaDEr, a variational autoencoder designed to perform unsupervised clustering and synthetic image generation using astronomical imaging catalogues. The model is a convolutional neural network that learns to embed images into…

Instrumentation and Methods for Astrophysics · Physics 2020-12-02 Ashley Spindler , James E. Geach , Michael J. Smith