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The rapid advancement of artificial intelligence, particularly autonomous agentic systems based on Large Language Models (LLMs), presents new opportunities to accelerate drug discovery by improving in-silico modeling and reducing dependence…

People frequently face challenging decision-making problems in which outcomes are uncertain or unknown. Artificial intelligence (AI) algorithms exist that can outperform humans at learning such tasks. Thus, there is an opportunity for AI…

Artificial Intelligence · Computer Science 2018-12-27 Ravi Pandya , Sandy H. Huang , Dylan Hadfield-Menell , Anca D. Dragan

AI agents -- systems that execute multi-step reasoning workflows with persistent state, tool access, and specialist skills -- represent a qualitative shift from prior automation technologies in social science. Unlike chatbots that respond…

Artificial Intelligence · Computer Science 2026-03-10 Yongjun Zhang

Securing AI agents powered by Large Language Models (LLMs) represents one of the most critical challenges in AI security today. Unlike traditional software, AI agents leverage LLMs as their "brain" to autonomously perform actions via…

Cryptography and Security · Computer Science 2025-11-25 Itay Hazan , Yael Mathov , Guy Shtar , Ron Bitton , Itsik Mantin

Penetration testing is a cornerstone of cybersecurity, traditionally driven by manual, time-intensive processes. As systems grow in complexity, there is a pressing need for more scalable and efficient testing methodologies. This systematic…

Software Engineering · Computer Science 2025-12-16 J. Alexander Curtis , Nasir U. Eisty

Cybersecurity is being fundamentally reshaped by foundation-model-based artificial intelligence. Large language models now enable autonomous planning, tool orchestration, and strategic adaptation at scale, challenging security architectures…

Cryptography and Security · Computer Science 2025-12-30 Tao Li , Quanyan Zhu

Artificial intelligence has made remarkable strides in recent years, achieving superhuman performance across a wide range of tasks. Yet despite these advances, most cooperative AI systems remain rigidly obedient, designed to follow human…

Artificial Intelligence · Computer Science 2025-06-30 Reuth Mirsky

Agentic AI scientists equipped with domain-specific tools are rapidly entering scientific workflows across disciplines, with especially strong uptake in the life sciences where they can be used for literature synthesis, sequence analysis,…

Other Quantitative Biology · Quantitative Biology 2026-05-05 Kimon Antonios Provatas , Avery Self , Ioannis Mouratidis , Ilias Georgakopoulos-Soares

Powerful artificial intelligence systems are often used in settings where they must interact with agents that are computationally much weaker, for example when they work alongside humans or operate in complex environments where some tasks…

Artificial Intelligence · Computer Science 2024-05-09 Karim Hamade , Reid McIlroy-Young , Siddhartha Sen , Jon Kleinberg , Ashton Anderson

Artificial intelligence (AI) systems are increasingly adopted as tool-using agents that can plan, observe their environment, and take actions over extended time periods. This evolution challenges current evaluation practices where the AI…

Cryptography and Security · Computer Science 2026-03-17 Simone Aonzo , Merve Sahin , Aurélien Francillon , Daniele Perito

Artificial Intelligence's dual-use nature is revolutionizing the cybersecurity landscape, introducing new threats across four main categories: deepfakes and synthetic media, adversarial AI attacks, automated malware, and AI-powered social…

Cryptography and Security · Computer Science 2026-01-08 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru

Agentic AI systems, built upon large language models (LLMs) and deployed in multi-agent configurations, are redefining intelligence, autonomy, collaboration, and decision-making across enterprise and societal domains. This review presents a…

Artificial Intelligence · Computer Science 2025-12-19 Shaina Raza , Ranjan Sapkota , Manoj Karkee , Christos Emmanouilidis

As benchmarks grow in complexity, many apparent agent failures are not failures of the agent at all - they are failures of the benchmark itself: broken specifications, implicit assumptions, and rigid evaluation scripts that penalize valid…

Computation and Language · Computer Science 2026-04-29 Xinming Tu , Tianze Wang , Yingzhou , Lu , Kexin Huang , Yuanhao Qu , Sara Mostafavi

Amongst the most common use cases of modern AI is LLM chat with web search enabled. However, no direct evaluations of the quality of web research agents exist that control for the continually-changing web. We introduce Deep Research Bench,…

Artificial Intelligence · Computer Science 2025-06-10 FutureSearch , : , Nikos I. Bosse , Jon Evans , Robert G. Gambee , Daniel Hnyk , Peter Mühlbacher , Lawrence Phillips , Dan Schwarz , Jack Wildman

Autonomous AI agents are deployed at unprecedented scale, yet no principled methodology exists for verifying that an agent has not regressed after changes to its prompts, tools, models, or orchestration logic. We present AgentAssay, the…

Artificial Intelligence · Computer Science 2026-03-04 Varun Pratap Bhardwaj

As AI agents increasingly operate in complex environments, ensuring reliable, context-aware privacy is critical for regulatory compliance. Traditional access controls are insufficient because privacy risks often arise after access is…

AI web agents use Internet resources at far greater speed, scale, and complexity -- changing how users and services interact. Deployed maliciously or erroneously, these agents could overload content providers. At the same time, web agents…

Artificial Intelligence · Computer Science 2025-09-03 Abhinav Kumar , Jaechul Roh , Ali Naseh , Amir Houmansadr , Eugene Bagdasarian

From automated intrusion testing to discovery of zero-day attacks before software launch, agentic AI calls for great promises in security engineering. This strong capability is bound with a similar threat: the security and research…

Cryptography and Security · Computer Science 2025-05-13 Brian Challita , Pierre Parrend

Evolving AI systems increasingly deploy multi-agent architectures where autonomous agents collaborate, share information, and delegate tasks through developing protocols. This connectivity, while powerful, introduces novel security risks.…

Cryptography and Security · Computer Science 2025-07-30 Gauri Sharma , Vidhi Kulkarni , Miles King , Ken Huang

When combining Large Language Models (LLMs) with autonomous agents, used in network monitoring and decision-making systems, this will create serious security issues. In this research, the MAESTRO framework consisting of the seven layers…

Cryptography and Security · Computer Science 2025-08-15 Pallavi Zambare , Venkata Nikhil Thanikella , Ying Liu