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Medical vision-language segmentation models suffer from catastrophic forgetting when adapting to new anatomical structures, requiring complete retraining that limits their clinical deployment. Although continual learning approaches have…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Ziyuan Gao

Deep learning for medical imaging suffers from temporal and privacy-related restrictions on data availability. To still obtain viable models, continual learning aims to train in sequential order, as and when data is available. The main…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Marius Memmel , Camila Gonzalez , Anirban Mukhopadhyay

Large Language Models (LLMs), pre-trained on massive text corpora, exhibit remarkable human-level language understanding, reasoning, and decision-making abilities. However, they tend to memorize unwanted information, such as private or…

Machine Learning · Computer Science 2026-01-01 Xiangyu Zhou , Yao Qiang , Saleh Zare Zade , Douglas Zytko , Prashant Khanduri , Dongxiao Zhu

When introducing Large Language Models (LLMs) into industrial applications, such as healthcare and education, the risk of generating harmful content becomes a significant challenge. While existing machine unlearning methods can erase…

Computation and Language · Computer Science 2026-04-08 Mutsumi Sasaki , Kouta Nakayama , Yusuke Miyao , Yohei Oseki , Masaru Isonuma

Multimodal AI systems have achieved remarkable performance across a broad range of real-world tasks, yet the mechanisms underlying visual-language reasoning remain surprisingly poorly understood. We report three findings that challenge…

Artificial Intelligence · Computer Science 2026-04-03 Mohammad Asadi , Jack W. O'Sullivan , Fang Cao , Tahoura Nedaee , Kamyar Rajabalifardi , Fei-Fei Li , Ehsan Adeli , Euan Ashley

Background: As of 2026, Large Language Models (LLMs) demonstrate expert-level medical knowledge. However, deploying them as autonomous "Clinical Agents" remains limited. Current Electronic Medical Records (EMRs) and standards like FHIR are…

Artificial Intelligence · Computer Science 2026-05-26 Takahito Nakajima

The significant computational demands of pretrained language models (PLMs), which often require dedicated hardware, present a substantial challenge in serving them efficiently, especially in multi-tenant environments. To address this, we…

Machine Learning · Computer Science 2025-04-25 Jun Zhang , Jue Wang , Huan Li , Lidan Shou , Ke Chen , Gang Chen , Qin Xie , Guiming Xie , Xuejian Gong

Misdiagnosis causes significant harm to healthcare systems worldwide, leading to increased costs and patient risks. MedRAG is a smart multimodal healthcare copilot equipped with powerful large language model (LLM) reasoning, designed to…

Artificial Intelligence · Computer Science 2025-06-04 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

Large language models (LLMs) are trained on massive datasets that may include private or copyrighted content. Due to growing privacy and ownership concerns, data owners may request the removal of their data from trained models. Machine…

Machine Learning · Computer Science 2026-01-13 Zhihao Liu , Jian Lou , Yuke Hu , Xiaochen Li , Yitian Chen , Tailun Chen , Zhizhen Qin , Kui Ren , Zhan Qin

Healthcare is becoming a more and more important research topic recently. With the growing data in the healthcare domain, it offers a great opportunity for deep learning to improve the quality of medical service. However, the complexity of…

Computation and Language · Computer Science 2021-11-01 Bo Yang , Lijun Wu

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Large Language Models (LLMs) inevitably acquire harmful information during training on massive datasets. LLM unlearning aims to eliminate the influence of such harmful information while maintaining the model's overall performance. Existing…

Computation and Language · Computer Science 2025-03-07 Wenyu Wang , Mengqi Zhang , Xiaotian Ye , Zhaochun Ren , Zhumin Chen , Pengjie Ren

Semi-supervised learning has become increasingly popular in medical image segmentation due to its ability to leverage large amounts of unlabeled data to extract additional information. However, most existing semi-supervised segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Shengbo Gao , Ziji Zhang , Jiechao Ma , Zihao Li , Shu Zhang

Privacy concerns associated with machine learning models have driven research into machine unlearning, which aims to erase the memory of specific target training data from already trained models. This issue also arises in federated…

Machine Learning · Computer Science 2025-03-14 Yuyuan Li , Jiaming Zhang , Yixiu Liu , Chaochao Chen

In healthcare, multi-organ system diseases pose unique and significant challenges as they impact multiple physiological systems concurrently, demanding complex and coordinated treatment strategies. Despite recent advancements in the AI…

Artificial Intelligence · Computer Science 2025-08-08 Daniel J. Tan , Qianyi Xu , Kay Choong See , Dilruk Perera , Mengling Feng

The development of artificial intelligence demands that models incrementally update knowledge by Continual Learning (CL) to adapt to open-world environments. To meet privacy and security requirements, Continual Unlearning (CU) emerges as an…

In recent years, unlearning techniques, which are methods for inducing a model to "forget" previously learned information, have attracted attention as a way to address privacy and copyright concerns in large language models (LLMs) and large…

Machine Learning · Computer Science 2025-10-29 Tatsuki Kawakami , Kazuki Egashira , Atsuyuki Miyai , Go Irie , Kiyoharu Aizawa

Large-scale EHR prediction across institutions is hindered by substantial heterogeneity in schemas and code systems. Although Common Data Models (CDMs) can standardize records for multi-institutional learning, the manual harmonization and…

Computation and Language · Computer Science 2026-04-02 Kyunghoon Hur , Heeyoung Kwak , Jinsu Jang , Nakhwan Kim , Edward Choi

Transformer-based large language models (LLM) have been widely used in language processing applications. However, due to the memory constraints of the devices, most of them restrict the context window. Even though recurrent models in…

Computation and Language · Computer Science 2025-02-07 Zifan He , Yingqi Cao , Zongyue Qin , Neha Prakriya , Yizhou Sun , Jason Cong

Medical image segmentation faces a fundamental challenge in continual learning: data arrives sequentially from heterogeneous sources, yet effective continual learning requires discovering which tasks share sufficient structure to benefit…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Ziyuan Gao