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Related papers: Predicting Polymer Solubility in Solvents Using SM…

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AI for drug discovery has been a research hotspot in recent years, and SMILES-based language models has been increasingly applied in drug molecular design. However, no work has explored whether and how language models understand the…

Machine Learning · Computer Science 2024-01-17 Xiuyuan Hu , Guoqing Liu , Yang Zhao , Hao Zhang

Polymer blends consisting of two or more polymers are important for a wide variety of industries and processes, but, the precise mechanism of their thermomechanical behaviour is incompletely understood. In order to understand clearly, it is…

Soft Condensed Matter · Physics 2021-01-12 Pashupati Pokharel , Feng Wei , Jianyi Shi , Yingmin Wang , Dequan Xiao

Machine learning techniques including neural networks are popular tools for materials and chemical scientists with applications that may provide viable alternative methods in the analysis of structure and energetics of systems ranging from…

Statistical Mechanics · Physics 2022-03-02 James Andrews , Olga Gkountouna , Estela Blaisten-Barojas

Mesoscale behavior of polymers is frequently described by universal laws. This physical property motivates us to propose a new modeling concept, grouping polymers into classes with a common long-wavelength representation. In the same class…

Soft Condensed Matter · Physics 2016-10-25 Guojie Zhang , Torsten Stuehn , Kostas Ch. Daoulas , Kurt Kremer

Hyperparameter optimization is very frequently employed in machine learning. However, an optimization of a large space of parameters could result in overfitting of models. In recent studies on solubility prediction the authors collected…

Machine Learning · Computer Science 2024-11-26 Igor V. Tetko , Ruud van Deursen , Guillaume Godin

Calculating polarizabilities of large clusters with first-principles techniques is challenging because of the unfavorable scaling of computational cost with cluster size. To address this challenge, we demonstrate that polarizabilities of…

Materials Science · Physics 2021-08-26 Mario G. Zauchner , Stefano Dal Forno , Gábor Cśanyi , Andrew Horsfield , Johannes Lischner

We performed a series of simulations for a linear polymer chain in a solvent using dissipative particle dynamics to check the scaling relations for the end-to-end distance, radius of gyration and hydrodynamic radius in three dimensions. The…

Soft Condensed Matter · Physics 2009-04-03 J. M. Ilnytskyi , Yu. Holovatch

We study bottlebrush macromolecules in a good solvent by small-angle neutron scattering (SANS), static light scattering (SLS), and dynamic light scattering (DLS). These polymers consist of a linear backbone to which long side chains are…

Soft Condensed Matter · Physics 2009-11-13 S. Bolisetty , C. Airaud , Y. Xu , A. H. E. Mueller , L. Harnau , S. Rosenfeldt , P. Lindner , M. Ballauff

Data scarcity, bias, and experimental noise are all frequently encountered problems in the application of deep learning to chemical and material science disciplines. Transfer learning has proven effective in compensating for the lack in…

Chemical Physics · Physics 2021-03-16 Florence H. Vermeire , William H. Green

We examine the phase transition of polymer adsorption as well as the underlying kinetics of polymer binding from dilute solutions on a structureless solid surface. The emphasis is put on the properties of regular multiblock copolymers,…

Soft Condensed Matter · Physics 2009-09-03 A. Milchev , V. Rostiashvili , S. Bhattacharya , T. Vilgis

Purpose: Large Language Models (LLMs) like GPT (Generative Pre-trained Transformer) from OpenAI and LLaMA (Large Language Model Meta AI) from Meta AI are increasingly recognized for their potential in the field of cheminformatics,…

Biomolecules · Quantitative Biology 2024-05-22 Shaghayegh Sadeghi , Alan Bui , Ali Forooghi , Jianguo Lu , Alioune Ngom

The need for analysis of toxicity in new drug candidates and the requirement of doing it fast have asked the consideration of scientists towards the use of artificial intelligence tools to examine toxicity levels and to develop models to a…

Quantitative Methods · Quantitative Biology 2021-01-27 Mriganka Nath , Subhasish Goswami

The increasing volume of drug combinations in modern therapeutic regimens needs reliable methods for predicting drug-drug interactions (DDIs). While Large Language Models (LLMs) have revolutionized various domains, their potential in…

Machine Learning · Computer Science 2025-02-12 Gabriele De Vito , Filomena Ferrucci , Athanasios Angelakis

Chemical autoencoders are attractive models as they combine chemical space navigation with possibilities for de-novo molecule generation in areas of interest. This enables them to produce focused chemical libraries around a single lead…

Machine Learning · Computer Science 2018-10-31 Esben Jannik Bjerrum , Boris Sattarov

From pasta to biological tissues to contact lenses, gel and gel-like materials inherently soften as they swell with water. In dry, low-relative-humidity environments, these materials stiffen as they de-swell with water. Here, we use…

Soft Condensed Matter · Physics 2021-09-29 Yiwei Gao , Nicholas K. K. Chai , Negin Garakani , Sujit S. Datta , H. Jeremy Cho

Predicting the solubility of given molecules remains crucial in the pharmaceutical industry. In this study, we revisited this extensively studied topic, leveraging the capabilities of contemporary computing resources. We employed two…

Quantitative Methods · Quantitative Biology 2024-01-08 John Ho , Zhao-Heng Yin , Colin Zhang , Nicole Guo , Yang Ha

The co-segregation of impurities in multicomponent alloys has been widely recognized as an effective strategy for tailoring material properties. However, quantitative predictions of co-segregation behavior remain a significant challenge for…

Materials Science · Physics 2026-04-23 Zuoyong Zhang , Chuang Deng

Active polymeric systems exhibit a rich spectrum of non-equilibrium phenomena arising from stochastic forces that explicitly break detailed balance. Despite the rapid growth of experimental and numerical studies, analytical progress remains…

Soft Condensed Matter · Physics 2026-03-09 Takahiro Sakaue , Enrico Carlon

Polymers underpin applications across energy, healthcare, and materials science, yet their vast chemical space makes systematic discovery challenging. Most machine learning approaches represent polymers as molecular graphs of a single…

Machine Learning · Computer Science 2026-05-27 Yasharth Yadav , Tze Kwang Gerald Er , Atsushi Goto , Kelin Xia

Modern data-driven tools are transforming application-specific polymer development cycles. Surrogate models that can be trained to predict the properties of new polymers are becoming commonplace. Nevertheless, these models do not utilize…