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The discovery of polymers with targeted properties is challenged by the vast chemical design space and the limited availability of consistent, high-quality data across multiple properties. In this work, an integrated polymer informatics…

Chemical Physics · Physics 2026-03-31 Sobin Alosious , Yuhan Liu , Jiaxin Xu , Gang Liu , Renzheng Zhang , Meng Jiang , Tengfei Luo

The simplified molecular-input line-entry system (SMILES) is the most popular representation of chemical compounds. Therefore, many SMILES-based molecular property prediction models have been developed. In particular, transformer-based…

Quantitative Methods · Quantitative Biology 2022-05-03 Ingoo Lee , Hojung Nam

Polymers are a versatile class of materials with widespread industrial applications. Advanced computational tools could revolutionize their design, but their complex, multi-scale nature poses significant modeling challenges. Conventional…

Machine-learning (ML) models in polymer science typically treat a polymer as a single, perfectly defined molecular graph, even though real materials consist of stochastic ensembles of chains with distributed lengths. This mismatch between…

Machine Learning · Computer Science 2025-12-16 Khalid Ferji

We use machine learning algorithms to detect the crystalline phase in undercooled melts in molecular dynamics simulations. Our classification method is based on local conformation and environmental fingerprints of individual monomers. In…

Soft Condensed Matter · Physics 2023-11-02 Atmika Bhardwaj , Jens-Uwe Sommer , Marco Werner

The development by machine learning of models predicting materials' properties usually requires the use of a large number of consistent data for training. However, quality experimental datasets are not always available or self-consistent.…

Materials Science · Physics 2019-01-29 Kai Yang , Xinyi Xu , Benjamin Yang , Brian Cook , Herbert Ramos , Mathieu Bauchy

All-atom molecular dynamics (MD) simulations can predict polymer properties from molecular structure, yet their execution requires specialized expertise in force field selection, system construction, equilibration, and property extraction.…

Computation and Language · Computer Science 2026-04-06 Alexander Zhao , Achuth Chandrasekhar , Amir Barati Farimani

We present a multimodal deep learning (MDL) framework for predicting physical properties of a 10-dimensional acrylic polymer composite material by merging physical attributes and chemical data. Our MDL model comprises four modules,…

Soft Condensed Matter · Physics 2023-11-28 Shun Muroga , Yasuaki Miki , Kenji Hata

Protein activity is a significant characteristic for recombinant proteins which can be used as biocatalysts. High activity of proteins reduces the cost of biocatalysts. A model that can predict protein activity from amino acid sequence is…

Quantitative Methods · Quantitative Biology 2018-07-23 X. Han , X. Wang , K. Zhou

Microfluidic devices are increasingly used in biological and chemical experiments due to their cost-effectiveness for rheological estimation in fluids. However, these devices often face challenges in terms of accuracy, size, and cost. This…

Synthetic polymers are versatile and widely used materials. Similar to small organic molecules, a large chemical space of such materials is hypothetically accessible. Computational property prediction and virtual screening can accelerate…

Machine Learning · Computer Science 2022-10-13 Matteo Aldeghi , Connor W. Coley

Large language models (LLMs) are increasingly recognized as powerful tools for scientific discovery, particularly in molecular science. A fundamental requirement for these models is the ability to accurately understand molecular structures,…

Machine Learning · Computer Science 2025-05-23 Yunhui Jang , Jaehyung Kim , Sungsoo Ahn

Accurate and efficient prediction of polymer properties is of key importance for polymer design. Traditional experimental tools and density function theory (DFT)-based simulations for polymer property evaluation, are both expensive and…

Materials Science · Physics 2024-10-08 Cong Shen , Yipeng Zhang , Fei Han , Kelin Xia

This paper addresses the challenge of geometric quality assurance in manufacturing, particularly when human assessment is required. It proposes using Blender, an open-source simulation tool, to create synthetic datasets for machine learning…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Joel Sol , Amir M. Soufi Enayati , Homayoun Najjaran

Research in AI4Science has shown promise in many science applications, including polymer design. However, current LLMs are ineffective in this problem space because: (i) most models lack polymer-specific knowledge, and (ii) existing aligned…

Computation and Language · Computer Science 2026-05-28 Dikshya Mohanty , Mohammad Saqib Hasan , Syed Mostofa Monsur , Size Zheng , Benjamin Hsiao , Niranjan Balasubramanian

This work aims to develop explainable models to predict the interactions between bitter molecules and TAS2Rs via traditional machine-learning and deep-learning methods starting from experimentally validated data. Bitterness is one of the…

Biomolecules · Quantitative Biology 2024-06-24 Francesco Ferri , Marco Cannariato , Lorenzo Pallante , Eric A. Zizzi , Marco A. Deriu

Polymers, composed of repeating structural units called monomers, are fundamental materials in daily life and industry. Accurate property prediction for polymers is essential for their design, development, and application. However, existing…

Machine Learning · Computer Science 2025-07-29 Jiaxi Wang , Yaosen Min , Xun Zhu , Miao Li , Ji Wu

The Saliency Model Implementation Library for Experimental Research (SMILER) is a new software package which provides an open, standardized, and extensible framework for maintaining and executing computational saliency models. This work…

Computer Vision and Pattern Recognition · Computer Science 2018-12-24 Calden Wloka , Toni Kunić , Iuliia Kotseruba , Ramin Fahimi , Nicholas Frosst , Neil D. B. Bruce , John K. Tsotsos

The tools and technology that are currently used to analyze chemical compound structures that identify polymer types in microplastics are not well-calibrated for environmentally weathered microplastics. Microplastics that have been degraded…

Machine Learning · Computer Science 2025-01-09 Sheela Ramanna , Danila Morozovskii , Sam Swanson , Jennifer Bruneau

Learning neural program embeddings is key to utilizing deep neural networks in program languages research --- precise and efficient program representations enable the application of deep models to a wide range of program analysis tasks.…

Software Engineering · Computer Science 2019-07-12 Ke Wang , Zhendong Su