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Electroencephalogram (EEG) is a common base signal used to monitor brain activity and diagnose sleep disorders. Manual sleep stage scoring is a time-consuming task for sleep experts and is limited by inter-rater reliability. In this paper,…

Signal Processing · Electrical Eng. & Systems 2019-06-19 Sajad Mousavi , Fatemeh Afghah , U. Rajendra Acharya

Sleep is an essential component of human physiology, contributing significantly to overall health and quality of life. Accurate sleep staging and disorder detection are crucial for assessing sleep quality. Studies in the literature have…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Kianoosh Kazemi , Iman Azimi , Michelle Khine , Rami N. Khayat , Amir M. Rahmani , Pasi Liljeberg

The Sleep Heart Health Study (SHHS) is a comprehensive landmark study of sleep and its impacts on health outcomes. A primary metric of the SHHS is the in-home polysomnogram, which includes two electroencephalographic (EEG) channels for each…

Applications · Statistics 2009-06-09 Chong-Zhi Di , Ciprian M. Crainiceanu , Brian S. Caffo , Naresh M. Punjabi

In this work we introduce a novel meta-learning method for sleep scoring based on self-supervised learning. Our approach aims at building models for sleep scoring that can generalize across different patients and recording facilities, but…

Machine Learning · Computer Science 2022-07-29 Abdelhak Lemkhenter , Paolo Favaro

Self-supervised learning (SSL) has emerged as a promising paradigm for addressing the annotation bottleneck in medical imaging by learning representations from unlabeled data. However, its effectiveness depends heavily on the design of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Chathura Wimalasiri

Much attention has been given to automatic sleep staging algorithms in past years, but the detection of discrete events in sleep studies is also crucial for precise characterization of sleep patterns and possible diagnosis of sleep…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Alexander Neergaard Olesen , Stanislas Chambon , Valentin Thorey , Poul Jennum , Emmanuel Mignot , Helge B. D. Sorensen

Accurate classification of sleep stages is crucial for diagnosing sleep disorders and automating this process can significantly enhance clinical assessments. This study aims to explore the use of a self-supervised model (more specifically,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Eldiane Borges dos Santos Durães , João Batista Florindo

Methods: We developed a self-supervised deep learning model that extracts meaningful patterns from multi-modal signals (Electroencephalography (EEG), Electrocardiography (ECG), and respiratory signals). The model was trained on data from…

Machine Learning · Computer Science 2025-07-15 Zhengxiao He , Huayu Li , Geng Yuan , William D. S. Killgore , Stuart F. Quan , Chen X. Chen , Ao Li

Electroencephalography foundation models (EEG-FMs) have advanced brain signal analysis, but the lack of standardized evaluation benchmarks impedes model comparison and scientific progress. Current evaluations rely on inconsistent protocols…

Signal Processing · Electrical Eng. & Systems 2026-02-16 Wei Xiong , Jiangtong Li , Jie Li , Kun Zhu , Changjun Jiang

Closed-loop sleep modulation is an emerging research paradigm to treat sleep disorders and enhance sleep benefits. However, two major barriers hinder the widespread application of this research paradigm. First, subjects often need to be…

Signal Processing · Electrical Eng. & Systems 2022-11-24 Mingzhe Sun , Aaron Zhou , Naize Yang , Yaqian Xu , Yuhan Hou , Xilin Liu

Objective: Evaluate a method for the estimation of the nocturnal systolic blood pressure (SBP) dip from 24-hour blood pressure trends using a wrist-worn photoplethysmography (PPG) sensor and a deep neural network in free-living individuals,…

Sleep studies are imperative to recapitulate phenotypes associated with sleep loss and uncover mechanisms contributing to psychopathology. Most often, investigators manually classify the polysomnography into vigilance states, which is…

Automation of sleep analysis, including both macrostructural (sleep stages) and microstructural (e.g., sleep spindles) elements, promises to enable large-scale sleep studies and to reduce variance due to inter-rater incongruencies. While…

Signal Processing · Electrical Eng. & Systems 2026-05-26 Niklas Grieger , Siamak Mehrkanoon , Philipp Ritter , Stephan Bialonski

Detecting arousals in sleep is essential for diagnosing sleep disorders. However, using Machine Learning (ML) in clinical practice is impeded by fundamental issues, primarily due to mismatches between clinical protocols and ML methods.…

Machine Learning · Computer Science 2024-09-23 Stefan Kraft , Andreas Theissler , Vera Wienhausen-Wilke , Philipp Walter , Gjergji Kasneci

Photoplethysmography (PPG) is a widely used non-invasive physiological sensing technique, suitable for various clinical applications. Such clinical applications are increasingly supported by machine learning methods, raising the question of…

Despite advances in deep learning for automatic sleep staging, clinical adoption remains limited due to challenges in fair model evaluation, generalization across diverse datasets, model bias, and variability in human annotations. We…

Artificial neural networks are often overconfident, undermining trust because their predicted probabilities do not match actual accuracy. Inspired by biological sleep and the role of spontaneous replay in memory and learning, we introduce…

Machine Learning · Computer Science 2026-03-10 Jean Erik Delanois , Aditya Ahuja , Giri P. Krishnan , Maxim Bazhenov

Predicting protein complex structures is essential for protein function analysis, protein design, and drug discovery. While AI methods like AlphaFold can predict accurate structural models for many protein complexes, reliably estimating the…

Biomolecules · Quantitative Biology 2025-05-30 Pawan Neupane , Jian Liu , Jianlin Cheng

Objective: Sleep related respiratory abnormalities are typically detected using polysomnography. There is a need in general medicine and critical care for a more convenient method to automatically detect sleep apnea from a simple,…

This paper proposes a practical approach for automatic sleep stage classification based on a multi-level feature learning framework and Recurrent Neural Network (RNN) classifier using heart rate and wrist actigraphy derived from a wearable…

Machine Learning · Statistics 2017-11-03 Xin Zhang , Weixuan Kou , Eric I-Chao Chang , He Gao , Yubo Fan , Yan Xu
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