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The problem of simultaneously testing the marginal distributions of sequentially monitored, independent data streams is considered. The decisions for the various testing problems can be made at different times, using data from all streams,…

Methodology · Statistics 2023-04-21 Yiming Xing , Georgios Fellouris

This paper presents a framework for incentivising colorectal cancer (CRC) screening programs from the perspective of policymakers and under the assumption that the citizens participating in the program have misaligned objectives. To do so,…

Applications · Statistics 2025-09-08 Daniel Corrales , David Rios Insua

The problem of corrupted data, missing features, or missing modalities continues to plague the modern machine learning landscape. To address this issue, a class of regularization methods that enforce consistency between imputed and fully…

Machine Learning · Computer Science 2026-02-03 Yinsong Wang , Shahin Shahrampour

A new approach to adaptive design of clinical trials is proposed in a general multiparameter exponential family setting, based on generalized likelihood ratio statistics and optimal sequential testing theory. These designs are easy to…

Statistics Theory · Mathematics 2011-05-25 Jay Bartroff , Tze Leung Lai

In a high-dimensional setting, sparse model has shown its power in computational and statistical efficiency. We consider variables selection problem with a broad class of simultaneous sparsity regularization, enforcing both feature-wise and…

Optimization and Control · Mathematics 2021-09-27 Xinyu Zhang

Mediation analysis in high-dimensional settings often involves identifying potential mediators among a large number of measured variables. For this purpose, a two step familywise error rate (FWER) procedure called ScreenMin has been…

Methodology · Statistics 2019-11-05 Vera Djordjilović , Jesse Hemerik , Magne Thoresen

Shortlisting is a common and effective method for pre-selecting participants in competitive settings. To ensure fairness, a cut-off score is typically announced, allowing only contestants who exceed it to enter the contest, while others are…

Computer Science and Game Theory · Computer Science 2026-02-13 Hanbing Liu , Ningyuan Li , Weian Li , Qi Qi , Changyuan Yu

In modern scientific research, small-scale studies with limited participants are increasingly common. However, interpreting individual outcomes can be challenging, making it standard practice to combine data across studies using random…

Statistics Theory · Mathematics 2025-11-04 Lucas Kania , Larry Wasserman , Sivaraman Balakrishnan

The sparsity-restricted maximum likelihood estimator (SMLE) has received considerable attention for feature screening in ultrahigh-dimensional regression. SMLE is a computationally convenient method that naturally incorporates the joint…

Other Statistics · Statistics 2022-01-11 Qianxiang Zang , Chen Xu , Kelly Burkett

The standard paradigm for confirmatory clinical trials is to compare experimental treatments with a control, for example the standard of care or a placebo. However, it is not always the case that a suitable control exists. Efficient…

Methodology · Statistics 2024-10-29 Thomas Burnett , Thomas Jaki

Compiler optimizations are designed to improve run-time performance while preserving input-output behavior. Correctness in this sense does not necessarily preserve security: it is known that standard optimizations may break or weaken…

Formal Languages and Automata Theory · Computer Science 2019-11-15 Kedar S. Namjoshi , Lucas M. Tabajara

We study random designs that minimize the asymptotic variance of a de-biased lasso estimator when a large pool of unlabeled data is available but measuring the corresponding responses is costly. The optimal sampling distribution arises as…

Statistics Theory · Mathematics 2020-10-27 Hamid Eftekhari , Moulinath Banerjee , Ya'acov Ritov

Existing methods in estimating the mean outcome under a given dynamic treatment regime rely on intention-to-treat analyses which estimate the effect of following a certain dynamic treatment regime regardless of compliance behavior of…

We investigate the performance of the scan (maximum likelihood ratio statistic) and of the average likelihood ratio statistic in the problem of detecting a deterministic signal with unknown spatial extent in the prototypical univariate…

Methodology · Statistics 2014-02-26 Hock Peng Chan , Guenther Walther

Causal effect estimation often succeeds cost-constrained sequential data collection. This work considers multivariate linear front-door models with arbitrary unobserved confounding on treatment and response. We optimize the experimental…

Methodology · Statistics 2026-03-24 Leopold Mareis , Mathias Drton

We consider the problem of designing an optimal quantum detector to minimize the probability of a detection error when distinguishing between a collection of quantum states, represented by a set of density operators. We show that the design…

Quantum Physics · Physics 2016-11-18 Yonina C. Eldar , Alexandre Megretski , George C. Verghese

There is a movement in design of experiments away from the classic randomization put forward by Fisher, Cochran and others to one based on optimization. In fixed-sample trials comparing two groups, measurements of subjects are known in…

Methodology · Statistics 2018-10-22 Adam Kapelner , Abba M. Krieger , Uri Shalit , David Azriel

In an observational study, it is common to leverage known null effect to detect bias. One such strategy is to set aside a placebo sample -- a subset of data immune from the hypothesized cause-and-effect relationship. Existence of an effect…

Methodology · Statistics 2022-07-05 Ting Ye , Shuxiao Chen , Bo Zhang

The goal of a well-controlled study is to remove unwanted variation when estimating the causal effect of the intervention of interest. Experiments conducted in the basic sciences frequently achieve this goal using experimental controls,…

Methodology · Statistics 2021-04-22 Kristen B. Hunter , Kristen Koenig , Marie-Abèle Bind

We study the design of one-to-one matching mechanisms that are strategy-proof for both sides and as stable as possible. Motivated by the impossibility result of Roth (1982), we formulate the mechanism design problem as a linear program that…

Theoretical Economics · Economics 2026-02-04 Tohya Sugano
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