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Presented are two techniques that are designed to help streamline the discretization of complex vascular geometries within the numerical modeling process. The first method integrates multiple software tools into a single pipeline which can…
In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain-supplying arteries, which are a…
Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…
Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…
The aorta is the body's largest arterial vessel, serving as the primary pathway for oxygenated blood within the systemic circulation. Aortic aneurysms consistently rank among the top twenty causes of mortality in the United States. Thoracic…
In this paper, we present our system for the RSNA Intracranial Hemorrhage Detection challenge. The proposed system is based on a lightweight deep neural network architecture composed of a convolutional neural network (CNN) that takes as…
Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…
Time-resolved three-dimensional flow MRI (4D flow MRI) provides a unique non-invasive solution to visualize and quantify hemodynamics in blood vessels such as the aortic arch. However, most current analysis methods for arterial 4D flow MRI…
Image-based, patient-specific modelling of hemodynamics can improve diagnostic capabilities and provide complementary insights to better understand the hemodynamic treatment outcomes. However, computational fluid dynamics simulations remain…
Background: Image reconstruction from highly undersampled 4D flow MRI data can be very time consuming and may result in significant underestimation of velocities depending on regularization, thereby limiting the applicability of the method.…
Physics-Informed Neural Networks (PINNs) show significant potential for solving inverse problems, especially when observations are limited and sparse, provided that the relevant physical equations are known. We use PINNs to estimate smooth…
Personalised 3D vascular models are valuable for diagnosis, prognosis and treatment planning in patients with cardiovascular disease. Traditionally, such models have been constructed with explicit representations such as meshes and voxel…
Graph neural networks, recently introduced into the field of fluid flow surrogate modeling, have been successfully applied to model the temporal evolution of various fluid flow systems. Existing applications, however, are mostly restricted…
This study leverages convolutional neural networks to enhance the temporal resolution of 3D angiography in intracranial aneurysms focusing on the reconstruction of volumetric contrast data from sparse and limited projections. Three…
Computational fluid dynamics (CFD) is a valuable tool for personalised, non-invasive evaluation of hemodynamics in arteries, but its complexity and time-consuming nature prohibit large-scale use in practice. Recently, the use of deep…
The left atrium (LA) plays a pivotal role in modulating left ventricular filling, but our comprehension of its hemodynamics is significantly limited by the constraints of conventional ultrasound analysis. 4D flow magnetic resonance imaging…
A weakness in the wall of a cerebral artery causing a dilation or ballooning of the blood vessel is known as a cerebral aneurysm. Optimal treatment requires fast and accurate diagnosis of the aneurysm. HemeLB is a fluid dynamics solver for…
Abdominal aortic aneurysms (AAA) pose a significant clinical risk due to their potential for rupture, which is often asymptomatic but can be fatal. Although maximum diameter is commonly used for risk assessment, diameter alone is…
Numerical simulations of blood flow are a valuable tool to investigate the pathophysiology of ascending thoracic aortic aneurysms (ATAA). To accurately reproduce hemodynamics, computational fluid dynamics (CFD) models must employ realistic…
Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…